WBGene00006832 | SMap | S_parent | Sequence | C41C4 |
| Identity (6) |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | unc |
| | Allele (115) |
| | Legacy_information | Class 3 (neomorphic) alleles n490sd : small hypercontracted rigid paralytic; very poor growth; abnormal muscle structure; n490/+ similar less severe phenotype. ES3. NA (dominant) 3 (n506 (ME0) n1274). Class 1 (loss-of-function) alleles; intragenic revertants of Class 3 alleles are probably null alleles e.g. n490n804 : wildtype phenotype no behavioral or muscular abnormality. NA (Class 1) > 10. Class 3 alleles also suppressed by mutations in unc-15 unc-22 unc-45 unc- 54 etc. |
| | | See also n490, n506, n785, n786, n787, n788, n795, n796, n797, n798, n799, n801, n802, n803, n804, n805, n806, n807, n808, n809, n810, n811, n812, n813, n814, n815, n816, n817, n818, n819, n820 |
| | | [Reiner D]] Mac-h (Hyper-ACtivate Muscle) |
| | | [C.elegansII] n490sd : small, hypercontracted, rigid paralytic; very poor growth; abnormal muscle structure. Muscle hyperactivated, sticky pumping, short.n490/+ similar but less severe phenotype. Probable neomorphic gf allele. Suppressed by mutations in unc-15, unc-22, unc-45, unc-54etc. See also sup-20.ES3. OA2 (gf): n506 (less severe; ME0), n1274. Also intragenic revertants: n490n804 (WT, no behavioral or muscular abnormality; probable null phenotype), n490n820 etc. OA>10 (ird). Cloned: encodes degenerin family member,related to amiloride-sensitive Na channels. [Park and Horvitz 1986b; MT; RW] |
| | Strain | WBStrain00026795 |
| | | WBStrain00026888 |
| | | WBStrain00026889 |
| | | WBStrain00026890 |
| | | WBStrain00026891 |
| | | WBStrain00027003 |
| | | WBStrain00032015 |
| | RNASeq_FPKM (74) |
| | GO_annotation (21) |
| | Ortholog (45) |
| | Paralog (30) |
| | Structured_description (2) |
| Disease_info | Potential_model | DOID:0080526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10600) |
| | | DOID:0050477 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10600,HGNC:10602) |
| | | DOID:4479 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10600,HGNC:10602) |
| | | DOID:0080528 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10602) |
| Molecular_info | Corresponding_CDS | C41C4.5a |
| | | C41C4.5b |
| | | C41C4.5c |
| | | C41C4.5d |
| | | C41C4.5e |
| | | C41C4.5h |
| | Corresponding_CDS_history | C41C4.5e:wp274 |
| | | C41C4.5f:wp274 |
| | | C41C4.5g:wp274 |
| | Corresponding_transcript | C41C4.5a.1 |
| | | C41C4.5b.1 |
| | | C41C4.5c.1 |
| | | C41C4.5c.2 |
| | | C41C4.5d.1 |
| | | C41C4.5e.1 |
| | | C41C4.5h.1 |
| | Other_sequence | Oden_isotig26078 |
| | | MH07095 |
| | | Oden_isotig19678 |
| | | JI175583.1 |
| | | JI170191.1 |
| | | Name_isotig03641 |
| | | Dviv_isotig27200 |
| | | GO239869.1 |
| | Associated_feature | WBsf644440 |
| | | WBsf654898 |
| | | WBsf657933 |
| | | WBsf988656 |
| | | WBsf988657 |
| | | WBsf1012649 |
| | | WBsf221685 |
| | | WBsf221686 |
| | | WBsf221687 |
| Experimental_info | RNAi_result | WBRNAi00029717 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00011833 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00042279 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00090191 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00109150 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00089804 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00042278 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00090032 | Inferred_automatically | RNAi_primary |
| | | WBRNAi00090350 | Inferred_automatically | RNAi_primary |
| | Expr_pattern | Expr1021485 |
| | | Expr1032895 |
| | | Expr1146269 |
| | | Expr2017835 |
| | | Expr2035971 |
| | Drives_construct | WBCnstr00034129 |
| | Construct_product | WBCnstr00034129 |
| | Microarray_results (37) |
| | Expression_cluster | WBPaper00030922:glycosylated_protein |
| | | WBPaper00031040:TGF-beta_adult_upregulated |
| | | WBPaper00033065:cyc-1(RNAi)_upregulated |
| | | WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq |
| | | WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray |
| | | WBPaper00040209:B.thuringiensis_upregulated_N2 |
| | | WBPaper00040221:DAF-12_target_ALF4 |
| | | WBPaper00042215:wdr-23(tm1817)_upregulated |
| | | WBPaper00042561:smgl-1(RNAi)_upregulated |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00044760:somatic_specific |
| | | WBPaper00045050:csr-1(hypomorph)_upregulated |
| | | WBPaper00045521:Spermatogenic |
| | | WBPaper00045774:clk-1_downregulated |
| | | WBPaper00046012:tdp-1(ok803)_upregulated |
| | | WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background |
| | | WBPaper00047132:skn-1(RNAi)_downregulated |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00049545:jmjd-3.1(+)_upregulated |
| | | WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated |
| | | WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated |
| | | WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo |
| | | WBPaper00050344:ASER-neuron_enriched |
| | | WBPaper00050488:adult_vs_dauer_regulated_N2_20C |
| | | WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C |
| | | WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C |
| | | WBPaper00050990:arcade_intestinal-valve_expressed |
| | | WBPaper00050990:GABAergic-neuron_expressed |
| | | WBPaper00051404:alg-1(gk214)_upregulated |
| | | WBPaper00051404:alg-2(ok304)_upregulated |
| | | WBPaper00051558:fog-2(q71)_regulated |
| | | WBPaper00053184:sma-4(rax3)_upregulated |
| | | WBPaper00053295:lin-22(icb38)_upregulated |
| | | WBPaper00053295:lin-22(ot267)_upregulated |
| | | WBPaper00053295:lin-22(ot269)_upregulated |
| | | WBPaper00053388:dauer_regulated_Cluster1 |
| | | WBPaper00054493:hpl-2(tm1489)_upregulated |
| | | WBPaper00054758:alg-1(gk204)_upregulated |
| | | WBPaper00055334:DLC-1_interacting |
| | | WBPaper00055354:Psora-Allantoin_downregulated |
| | | WBPaper00055354:Rapamycin-Allantoin_downregulated |
| | | WBPaper00055354:Rapamycin-Metformin_downregulated |
| | | WBPaper00055354:Rifampicin-Allantoin_downregulated |
| | | WBPaper00055626:pry-1(mu38)_downregulated |
| | | WBPaper00055971:nhl-2(ok818)_25C_downregulated |
| | | WBPaper00056034:pals-22(jy3)_upregulated |
| | | WBPaper00056284:ints-11(RNAi)_downregulated |
| | | WBPaper00056471:S.aureus-4h_downregulated_N2 |
| | | WBPaper00056617:adr-1_upregulated_embryo_transcript |
| | | WBPaper00056826:SGP_biased |
| | | WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C |
| | | WBPaper00057041:unc-70(cas983)_upregulated |
| | | WBPaper00058598:mex-1(or286)_upregulated |
| | | WBPaper00058598:mex-3(eu149)_upregulated |
| | | WBPaper00058598:sin-3(tm1276)_downregulated |
| | | WBPaper00058598:spn-4(tm291)_upregulated |
| | | WBPaper00058725:sftb-1(cer6)_downregulated |
| | | WBPaper00058969:RIS_depleted |
| | | WBPaper00059664:srbc-48(ac23)_upregulated |
| | | WBPaper00059728:20ug_cholesterol_upregulated |
| | | WBPaper00060273:isp-1(qm150)_upregulated |
| | | WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi) |
| | | WBPaper00060526:plp-1(ok2155)_upregulated |
| | | WBPaper00060683:hlh-11(ko1)_upregulated |
| | | WBPaper00060886:met-2(n4256)_downregulated |
| | | WBPaper00061007:S.aquatilis_upregulated |
| | | WBPaper00061203:sin-3(tm1276)_upregulated |
| | | WBPaper00061203:spr-1(ok2144)_upregulated |
| | | WBPaper00061340:BWM_far_posterior |
| | | WBPaper00061340:mu_int_mu_anal |
| | | WBPaper00061341:28C_48h_upregulated |
| | | WBPaper00061439:unc-30(ok613)_downregulated |
| | | WBPaper00061466:nath-10(icb102)_downregulated |
| | | WBPaper00061479:mep-1(ne4629)_upregulated |
| | | WBPaper00061527:myo-3-Y71G12B.11_22540 |
| | | WBPaper00061651:RIF_enriched |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062193:skn-1(RNAi)_downregulated |
| | | WBPaper00062325:muscle_enriched_coding-RNA |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064306:Agaro-oligosaccharides_upregulated |
| | | WBPaper00064769:him-17(me24)_upregulated |
| | | WBPaper00065096:25C_vs_20C_downregulated |
| | | WBPaper00065096:Day10_vs_Day1_downregulated |
| | | WBPaper00065835:Day5_vs_Day1_downregulated |
| | | WBPaper00065835:Day11_vs_Day1_downregulated |
| | | WBPaper00065841:1_1 |
| | | WBPaper00065841:4_0 |
| | | WBPaper00065841:7_1 |
| | | WBPaper00065841:7_2 |
| | | WBPaper00065841:11_2 |
| | | WBPaper00065841:38_0 |
| | | WBPaper00065841:38_2 |
| | | WBPaper00065841:55_0 |
| | | WBPaper00065841:58_0 |
| | | WBPaper00065975:P-body_vs_WholeAnimal_depleted |
| | | WBPaper00065993:glp-1(e2141)_upregulated |
| | | WBPaper00066062:xrep-4(lax137)_upregulated |
| | | cgc4489_male_enriched_neuronal_genes |
| | | WBPaper00026929:sir-2.1_overexpression_regulated |
| | | WBPaper00030985:Serratia_marcesens_downregulated |
| | | WBPaper00031003:24hr_muscle_enriched |
| | | WBPaper00031003:total_muscle_enriched |
| | | WBPaper00031252:AIN-1_IP_enriched |
| | | WBPaper00031252:AIN-2_IP_enriched |
| | | WBPaper00034739:N2moreDR1350 |
| | | WBPaper00035084:L3_enriched_AIN-2_IP |
| | | WBPaper00036286:Pattern_C |
| | | WBPaper00040858:eQTL_age_regulated_developing |
| | | WBPaper00040858:eQTL_regulated_developing |
| | | WBPaper00040858:eQTL_regulated_juvenile |
| | | WBPaper00040876:mir-35_downregulated |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h |
| | | WBPaper00045673:colistin_upregulated |
| | | WBPaper00048989:N2_rapamycin_upregulated |
| | | WBPaper00053236:Starvation_regulated_N2 |
| | | [cgc5376]:let-60(G12V)-regulated_genes |
| | | [cgc6390]:Cluster_B |
| | Interaction (54) |
| | WBProcess | WBbiopr:00000002 |
| Map_info | Map | II | Position | 0.689401 | Error | 0.004244 |
| | Well_ordered |
| | Positive | Positive_clone | C41C4 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Mapping_data | 2_point | 778 |
| | | | 779 |
| | | | 780 |
| | | Multi_point (11) |
| | | Pos_neg_data | 1362 |
| | | | 1430 |
| | | | 1435 |
| | | | 1440 |
| | | | 1445 |
| | | | 1449 |
| | | | 1453 |
| | | | 1486 |
| Reference (67) |
| Method | Gene |