WormBase Tree Display for Gene: WBGene00004481

WBGene00004481 SMap: S_parent: Sequence: F54E7
  Identity: Version: 1
    Name: CGC_name: rps-12
      Sequence_name: F54E7.2
      Molecular_name: F54E7.2
        F54E7.2.1
        CE26896
        F54E7.2.2
        F54E7.2.3
        F54E7.2.4
      Other_name: CELE_F54E7.2 Accession_evidence: NDB BX284603
      Public_name: rps-12
    DB_info: Database: AceView gene 3G769
        WormQTL gene WBGene00004481
        WormFlux gene WBGene00004481
        NDB locus_tag CELE_F54E7.2
        Panther gene CAEEL|WormBase=WBGene00004481|UniProtKB=P49196
          family PTHR11843
        NCBI gene 175786
        RefSeq protein NM_065820.8
        SwissProt UniProtAcc P49196
        TREEFAM TREEFAM_ID TF300196
        UniProt_GCRP UniProtAcc P49196
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:35 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: rps
    Allele (21)
    Legacy_information: Orthologous to yeast (S.cerevisiae) ribosomal protein rps12 using blastP
    RNASeq_FPKM (72)
    GO_annotation (11)
    Contained_in_operon: CEOP3316
    Ortholog (39)
    Structured_description: Concise_description: rps-12 encodes a small ribosomal subunit S12 protein; by homology, RPS-12 is predicted to function in protein biosynthesis; in C. elegans, RPS-12 activity is required for embryonic and germline development, normal movement, and the overall health of the animal. Paper_evidence: WBPaper00004403
            WBPaper00005654
          Curator_confirmed: WBPerson1843
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal small subunit biogenesis. Predicted to be located in nucleolus and ribosome. Predicted to be part of cytosolic small ribosomal subunit and small-subunit processome. Is an ortholog of human RPS12 (ribosomal protein S12). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F54E7.2
    Corresponding_transcript: F54E7.2.1
      F54E7.2.2
      F54E7.2.3
      F54E7.2.4
    Other_sequence (261)
    Associated_feature: WBsf645194
      WBsf645195
      WBsf658981
      WBsf981484
      WBsf1014935
      WBsf224977
  Experimental_info: RNAi_result (21)
    Expr_pattern (5)
    Drives_construct: WBCnstr00035452
    Construct_product: WBCnstr00035452
    Microarray_results (20)
    Expression_cluster: WBPaper00027057:DCR-1_interacting_embryo
      WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00031674:feh-1(gb561)(RNAi)_downregulated
      WBPaper00032528:L3_enriched
      WBPaper00035963:S.aureus_4h_downregulated
      WBPaper00035963:S.aureus_8h_downregulated
      WBPaper00035963:S.aureus_24h_downregulated
      WBPaper00037047:insoluble_protein
      WBPaper00037109:cyclophilin-inhibitor_regulated
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038118:aak-2(gt33)_downregulated
      WBPaper00038118:stress_downregulated_N2
      WBPaper00038289:oocyte_protein
      WBPaper00038357:atx-3_regulated_heat-shock
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00040446:insoluble_protein
      WBPaper00040965:lipid-droplet_associated_protein
      WBPaper00041072:UTX-1_interacting_protein
      WBPaper00043951:insoluble_protein_day16_N2
      WBPaper00043951:Nascent-polypeptide-associated
      WBPaper00044128:DietaryRestriction_downregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_downregulated_HeatShock
      WBPaper00045050:drh-3 (ne4253)_downregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045974:NSM_enriched_totalRNA_RNAseq
      WBPaper00046691:P1_enriched
      WBPaper00048644:germline_enriched
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049217:DAF-16_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00049942:HeatShock_upregulated_hsf-1(+)
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050163:chd-3(eh4)_downregulated_24-cell-embryo
      WBPaper00050225:flp-6(RNAi)_downregulated
      WBPaper00050636:aging_regulated_insoluble_protein
      WBPaper00050698:DEP-1_interacting
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:cytoplasm_specific
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00051265:F4_morc-1(tm6048)_downregulated
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053289:DREAM-target
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053321:embryo-to-L1_upregulated_nos-1(gv5)nos-2(RNAi)_SMARTseq
      WBPaper00053388:dauer_regulated_Cluster6
      WBPaper00053599:oocyte_vs_mitosis_upregulated
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053814:25C_downregulated_OP50
      WBPaper00053814:25C_downregulated_PY79
      WBPaper00055049:S.gordonii_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00055897:heat-shock_upregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056826:SGP_biased
      WBPaper00056900:ERH-2_interacting
      WBPaper00056900:PID-3_interacting
      WBPaper00056900:TOFU-6_interacting
      WBPaper00056997:NMAD-1_interacting
      WBPaper00057083:daf-2(e1370)rsks-1(ok1255)_post-transcriptional_downregulated
      WBPaper00057288:iff-1(RNAi)_upregulated_transcript
      WBPaper00058691:set-2(bn129)_downregulated
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00058958:100mGy-irradiation-72h_upregulated
      WBPaper00059254:CSR-1_interacting
      WBPaper00059254:PRG-1_interacting
      WBPaper00059254:WAGO-1_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059605:MUT-16_interacting
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060871:M.humicola-infection_12h_regulated
      WBPaper00060871:M.humicola-infection_24h_regulated
      WBPaper00061274:hypergravity_15xg_downregulated
      WBPaper00061285:wounding_24h_upregulated
      WBPaper00061340:Excretory_cell
      WBPaper00061340:M_cell
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061377:MYRF-1_interacting
      WBPaper00061377:MYRF-2_interacting
      WBPaper00061377:PAN-1_interacting
      WBPaper00061390:daf-22(ok693)_ascarosides_downregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061527:rps-14_21270-rps-11_20714
      WBPaper00061530:nhr-49(e2144)_downregulated
      WBPaper00061651:ADA_enriched
      WBPaper00061651:ADE_enriched
      WBPaper00061651:CAN_enriched
      WBPaper00061651:Distal_tip_cell_enriched
      WBPaper00061651:Excretory_gland_cell_enriched
      WBPaper00061651:Germline_enriched
      WBPaper00061651:Gonadal_sheath_cell_enriched
      WBPaper00061651:RID_enriched
      WBPaper00061651:RIG_enriched
      WBPaper00061651:RIH_enriched
      WBPaper00061651:RMG_enriched
      WBPaper00061651:Spermatheca_enriched
      WBPaper00061651:URB_enriched
      WBPaper00061651:URX_enriched
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062143:PQN-59_interacting
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:etr-1(lq61)_downregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062590:Aging_upregulated_hypodermis
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064055:trl-1(cas1077)_downregulated_non-starved
      WBPaper00064055:trl-1(cas1077)_downregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064163:ZNFX-1_interacting_embryo
      WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
      WBPaper00064933:E.coli-binding_secret_protein
      WBPaper00065149:lin-52(n771)_downregulated
      WBPaper00065158:25C_vs_15C_downregulated_WholeAnimal
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_Ref
      WBPaper00065945:epidermis-rpoa-2(-)_downregulated_protein
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066085:hda-3(ok1991)_downregulated
      WBPaper00066085:sin-3(syb2172)_downregulated
      cgc4386_cluster_1_5
      cgc4489_group_3
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00025032:cluster_120
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00028564:CeMM_vs_NGM_upregulated
      WBPaper00035479:daf-16(RNAi)_upregulated
      WBPaper00036286:Pattern_H
      WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated
      WBPaper00040998:nhr-80_regulated
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00042548:miRISC_enriched
      WBPaper00048989:eat-2(ad465)_downregulated_in-DMSO
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:cluster_16
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(66_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
    Interaction (178)
  Map_info: Map: III Position: -1.45858 Error: 0.000827
    Positive: Positive_clone: F54E7 Inferred_automatically: From CDS info
            From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00024230
    WBPaper00028564
    WBPaper00029197
    WBPaper00038356
    WBPaper00038491
    WBPaper00049828
    WBPaper00055090
    WBPaper00065012
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene