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WormBase Tree Display for Gene: WBGene00003531

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Name Class

WBGene00003531EvidenceAuthor_evidenceMoehrlen F
SMapS_parentSequenceCHROMOSOME_IV
IdentityVersion1
NameCGC_namenas-12Person_evidenceWBPerson1103
Sequence_nameC24F3.3
Molecular_nameC24F3.3
C24F3.3.1
CE35408
Other_nameCELE_C24F3.3Accession_evidenceNDBBX284604
Public_namenas-12
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:32WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classnas
Allele (37)
StrainWBStrain00002662
RNASeq_FPKM (74)
GO_annotation (12)
Ortholog (32)
Paralog (48)
Structured_descriptionConcise_descriptionnas-12 encodes an astacin-like metalloprotease; large-scale expression studies reveal that a nas-12::GFP promoter fusion is expressed in the intestine and in the pharyngeal and rectal gland cells.Paper_evidenceWBPaper00006254
WBPaper00006525
WBPaper00031006
Curator_confirmedWBPerson1843
Date_last_updated15 Feb 2008 00:00:00
Automated_descriptionPredicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Expressed in g1AL; g1AR; g1P; g2L; and g2R.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSC24F3.3
Corresponding_CDS_historyC24F3.3:wp109
Corresponding_transcriptC24F3.3.1
Other_sequenceFD515450.1
CSC01859_1
Associated_featureWBsf646293
WBsf660572
WBsf228966
Experimental_infoRNAi_resultWBRNAi00011112Inferred_automaticallyRNAi_primary
WBRNAi00041093Inferred_automaticallyRNAi_primary
WBRNAi00088991Inferred_automaticallyRNAi_primary
WBRNAi00029148Inferred_automaticallyRNAi_primary
Expr_pattern (7)
Drives_constructWBCnstr00003205
WBCnstr00013607
WBCnstr00015504
WBCnstr00036065
Construct_productWBCnstr00013607
WBCnstr00036065
Microarray_results (22)
Expression_clusterWBPaper00036738:4uM_Heme_upregulated
WBPaper00036738:500uM_Heme_upregulated
WBPaper00037055:DAF-16_binding_DNA
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
WBPaper00040221:DAF-12_target_ALF4
WBPaper00042477:rsr-2(RNAi)_downregulated_TilingArray
WBPaper00044316:CH3HgCl_7.5uM_downregulated
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044736:oscillating_dev_expression
WBPaper00044760:somatic_specific
WBPaper00045417:128Q-huntingtin_downreglated
WBPaper00045774:clk-1_downregulated
WBPaper00045934:wrn-1(gk99)_downregulated
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00050370:dpy-21(e428)_L3_downregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050801:DAF-12_dauer_regulome
WBPaper00050801:DAF-16_dauer_regulome
WBPaper00050801:DPY-21_dauer_regulome
WBPaper00050843:sesamin_downregulated
WBPaper00051558:aging_regulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053402:cco-1(RNAi)_downregulated
WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
WBPaper00053771:down_by_skn-1(RNAi)_at_dpy-7(e88)
WBPaper00053810:daf-2(e1370)_downregulated
WBPaper00053810:isp-1(qm150)_downregulated
WBPaper00053810:nuo-6(qm200)_downregulated
WBPaper00055013:hmg-3(bar24)_downregulated
WBPaper00055354:Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Metformin_downregulated
WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin_downregulated
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055354:Rifampicin-Psora_downregulated
WBPaper00055386:daf-2(e1370)_upregulated
WBPaper00055827:daf-2(e1370)_upregulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00057068:ints-4(RNAi)_downregulated
WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium
WBPaper00058598:mex-1(or286)_upregulated
WBPaper00058598:mex-3(eu149)_upregulated
WBPaper00058598:sin-3(tm1276)_downregulated
WBPaper00058598:spn-4(tm291)_upregulated
WBPaper00059117:B.subtilis_upregulated
WBPaper00059231:alh-6(lax105)_L4_upregulated
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059728:5ug_cholesterol_upregulated
WBPaper00059728:20ug_cholesterol_upregulated
WBPaper00060014:set-2(tm1630)_downregulated
WBPaper00060014:set-2(zr2012)_downregulated
WBPaper00060434:pH4.33_vs_pH6.33_uprgulated
WBPaper00060909:atfs-1(cmh15)_upregulated
WBPaper00060909:atfs-1(et18)_downregulated
WBPaper00061007:HB101_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061340:CEPsh
WBPaper00061340:g1A
WBPaper00061340:g1P
WBPaper00061341:28C_24h_upregulated
WBPaper00061341:28C_48h_upregulated
WBPaper00061439:unc-30(ok613)_downregulated
WBPaper00061527:R12A1.3-M195.2
WBPaper00061653:alh-4(hj221)_upregulated
WBPaper00062156:jmjd-1.2(zr1010)_upregulated
WBPaper00062156:jmjd-5(zr1234)_upregulated
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062325:muscle_depleted_coding-RNA
WBPaper00062446:nhr-8(hd117)_upregulated
WBPaper00062456:doxycycline_upregulated_N2_transcript
WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium
WBPaper00062590:Aging_downregulated_neuron
WBPaper00064107:lin-35(n745)_downregulated
WBPaper00064315:mes-3(bn199)_upregulated_EGCs
WBPaper00065074:glna(-)_downregulated
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065623:164
WBPaper00065746:eat-2(ad1113)_downregulated
WBPaper00065841:89_0
WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose
WBPaper00065993:glp-1(e2141)_downregulated
WBPaper00005124:estrogen_10-5M_regulated
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026952:class_E
WBPaper00031703:heme_responsive_5
WBPaper00031832:slr-2_regulated
WBPaper00032948:FedUp
WBPaper00035588:alg-1(-)_upregulated
WBPaper00036130:mir-243_up_regulated
WBPaper00038172:aak-2overexpression_up_regulated
WBPaper00041174:environmental
WBPaper00041174:environmental_prime
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_EtBr-exposed_51h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00045294:50uM_TBBP_upregulated
WBPaper00045673:colistin_upregulated
WBPaper00045960:L1-L4-lethargus_upregulated
WBPaper00045960:L4-lethargus_upregulated
WBPaper00046083:pmk-1(km25)_OP50_downregulated
WBPaper00047070:N2_starvation_downregulated
WBPaper00047070:N2_UV_downregulated
WBPaper00047070:xpa-1_UV_downregulated
WBPaper00056330:mrps-5(RNAi)_upregulated
InteractionWBInteraction000177452
WBInteraction000179826
WBInteraction000254746
WBInteraction000255496
WBInteraction000268072
WBInteraction000328233
WBInteraction000394191
WBInteraction000438853
WBInteraction000460519
Map_infoMapIVPosition4.56187
PositivePositive_cloneC24F3Inferred_automaticallyFrom CDS info
From sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00006254
WBPaper00038491
WBPaper00041256
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene