WormBase Tree Display for Gene: WBGene00002247

WBGene00002247 SMap: S_parent: Sequence: W03F8
  Identity: Version: 2
    Name: CGC_name: lam-1 Person_evidence: WBPerson1052
      Sequence_name: W03F8.5
      Molecular_name: W03F8.5a
        W03F8.5a.1
        CE47338
        W03F8.5b
        CE49160
        W03F8.5b.1
      Other_name: LAMB/1
        CELE_W03F8.5 Accession_evidence: NDB BX284604
      Public_name: lam-1
    DB_info: Database: AceView gene 4F943
        WormQTL gene WBGene00002247
        WormFlux gene WBGene00002247
        NDB locus_tag CELE_W03F8.5
        Panther gene CAEEL|WormBase=WBGene00002247|UniProtKB=O44565
          family PTHR10574
        NCBI gene 177292
        RefSeq protein NM_068333.6
            NM_001380214.1
        TrEMBL UniProtAcc V6CIX7
            O44565
        UniProt_GCRP UniProtAcc O44565
        OMIM gene 150240
            150310
            150325
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:27 WBPerson1971 Event: Imported: Initial conversion from geneace
        2 30 Jan 2012 16:23:16 WBPerson1867 Event: Acquires_merge: WBGene00020998
      Acquires_merge: WBGene00020998
    Status: Live
  Gene_info (11)
  Disease_info: Potential_model: DOID:5409 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6490)
      DOID:3908 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6490)
      DOID:0080380 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6487)
      DOID:1070 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6487)
      DOID:12849 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6486)
      DOID:3209 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6490)
      DOID:0110054 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6490)
      DOID:0112230 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6486)
      DOID:0060852 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6487)
  Molecular_info: Corresponding_CDS: W03F8.5a
      W03F8.5b
    Corresponding_CDS_history: W03F8.5:wp101
      W03F8.5:wp230
    Corresponding_transcript: W03F8.5a.1
      W03F8.5b.1
    Other_sequence (45)
    Associated_feature (11)
  Experimental_info: RNAi_result (20)
    Expr_pattern: Expr3984
      Expr10827
      Expr1019727
      Expr1031321
      Expr1158236
      Expr1158240
      Expr2013007
      Expr2031239
    Drives_construct: WBCnstr00005458
      WBCnstr00005751
      WBCnstr00006684
      WBCnstr00008702
      WBCnstr00008703
      WBCnstr00008704
      WBCnstr00008752
      WBCnstr00022483
      WBCnstr00024738
    Construct_product: WBCnstr00005458
      WBCnstr00005751
      WBCnstr00008752
      WBCnstr00017755
      WBCnstr00022483
      WBCnstr00022851
      WBCnstr00024738
    Microarray_results (37)
    Expression_cluster: WBPaper00005700:secreted_protein
      WBPaper00024276:N-glycosylated_protein
      WBPaper00024505:pharyngeal_enriched
      WBPaper00030922:glycosylated_protein
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00033070:Elbe_downregulated
      WBPaper00035073:mitochondria_protein
      WBPaper00037047:aging_accelerated_insoluble_protein
      WBPaper00037047:insoluble_protein
      WBPaper00037950:bodywall-muscle_CoreEnriched
      WBPaper00037950:bodywall-muscle_embryo_enriched
      WBPaper00037950:bodywall-muscle_embryo_SelectivelyEnriched
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_larva_enriched
      WBPaper00037950:bodywall-muscle_larva_SelectivelyEnriched
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:intestine_embryo_enriched
      WBPaper00037950:intestine_embryo_SelectivelyEnriched
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038289:oocyte_protein
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044128:daf-2(e1370)_downregulated
      WBPaper00044246:pgrn-1_ced-1_downregulated
      WBPaper00044260:1-methylnicotinamide_downregulated
      WBPaper00044260:nicotic-acid_downregulated
      WBPaper00044316:CH3HgCl_7.5uM_downregulated
      WBPaper00044426:rotenone_5day_downregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045521:Oogenic
      WBPaper00045774:clk-1_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00048923:Aging_regulated
      WBPaper00048971:daf-16(mgDf50)_upregulated_L1
      WBPaper00048988:daf-2(e1370)_daf-16(mu86)_upregulated_neuron
      WBPaper00048988:daf-16(mu86)_upregulated_neuron
      WBPaper00048988:neuron_expressed
      WBPaper00049159:Microwave_upregulated_adult
      WBPaper00049217:DAF-16_downregulated
      WBPaper00049498:npr-1(ur89)_regulated_3
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:daf-2(e1370)_vs_daf-2(e1370);mir-34(gk437)_regulated_dauer_25C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050636:aging_regulated_insoluble_protein
      WBPaper00050686:glp-1(e2141)_upregulated
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:cytoplasm_specific
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed
      WBPaper00051265:F4_hrde-1(tm1200)_upregulated
      WBPaper00051265:F4_morc-1(tm6048)_upregulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:embryo-to-L1_downregulated_WT_SMARTseq
      WBPaper00053321:lin-15B(RNAi)_downregulated_starved-L1_Truseq
      WBPaper00053321:mes-4(RNAi)_downregulated_fed-L1_Truseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_L1_SMARTseq
      WBPaper00053321:nos-1(gv5)nos-2(RNAi)_upregulated_starved-L1_Truseq
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053599:female_vs_male_upregulated
      WBPaper00053599:mitosis_vs_meiosis_downregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053814:15C_downregulated_OP50
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00054493:hpl-2(tm1489)_upregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055334:DLC-1_interacting
      WBPaper00055354:Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Metformin_upregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055482:pmt-2(RNAi)_downregulated
      WBPaper00055969:electromagnetic-field_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056139:gut-microbiota_downregulated
      WBPaper00056218:daf-16(mu86)_upregulated_Day7
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056826:hmc_biased
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00057154:HeatShock_downregulated_miRNA-target
      WBPaper00057154:HeatShock_upregulated_mRNA
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058969:RIS_depleted
      WBPaper00059027:neuron-synapses_enriched
      WBPaper00059174:MEG-3_interacting
      WBPaper00059224:tph-1(mg280)_upregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059328:mrps-5(RNAi)_downregulated_protein
      WBPaper00059334:SACY-1_interacting
      WBPaper00059605:MUT-16_interacting
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060683:hlh-11(overexpression)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:Body_wall_muscle
      WBPaper00061340:GLR
      WBPaper00061340:Intestinal_and_rectal_muscle
      WBPaper00061340:M1_parent
      WBPaper00061478:SUMO-conjugated_protein
      WBPaper00061527:tub-2_4713-daf-2_5288
      WBPaper00061527:unc-120-pat-4_1597
      WBPaper00061651:Distal_tip_cell_enriched
      WBPaper00061818:AFD_enriched_protein
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064055:trl-1(cas1077)_upregulated_starved
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064122:vulva_transcriptome
      WBPaper00064315:mes-3(bn199)_upregulated_EGCs
      WBPaper00064315:mes-4(bn73)_upregulated_EGCs
      WBPaper00064502:spe-44(fx110)_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064933:E.coli-binding_secret_protein
      WBPaper00064939:vit-5(RNAi)_upregulated
      WBPaper00064992:heat-shock_upregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065225:nhr-42(tm1375)_upregulated_S.aureus-infected
      WBPaper00065315:mating_upregulated_Day2-7
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065623:85
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065841:1_1
      WBPaper00065841:1_2
      WBPaper00065841:4_0
      WBPaper00065841:7_0
      WBPaper00065841:7_1
      WBPaper00065841:7_2
      WBPaper00065841:7_3
      WBPaper00065841:7_4
      WBPaper00065841:31_0
      WBPaper00065841:38_0
      WBPaper00065841:38_1
      WBPaper00065841:38_2
      WBPaper00065841:38_3
      WBPaper00065841:102_0
      WBPaper00065841:110_0
      WBPaper00065975:P-body_vs_oocyte_enriched
      WBPaper00065975:P-body_vs_WholeAnimal_enriched
      cgc4489_group_23
      WBPaper00025032:cluster_10
      WBPaper00025032:cluster_12
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00031003:hlh_1_enriched
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00036286:Pattern_I
      WBPaper00038060:SUMO-1_upregulated
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040876:mir-35_upregulated
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041174:environmental
      WBPaper00041174:environmental_prime
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041960:N2_fasting_upregulated_9hto12h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042274:tbx-2(bx59)_downregulated
      WBPaper00046639:tyrosol_upregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00050407:hsp-6(RNAi)_downregulated
      WBPaper00053550:daf-19(m86)_upregulated_L1
    Interaction (39)
    Anatomy_function: WBbtf0735
      WBbtf0736
  Map_info: Map: IV Position: 1.55302 Error: 0.001128
    Positive: Positive_clone (3)
    Mapping_data: Multi_point: 4471
        5450
    Pseudo_map_position
  Reference (28)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene