gly-20 encodes an N-acetylglucosaminyltransferase II (GnTII); by homology, GLY-20 is predicted to function in the Golgi to effect protein N-glycosylation; expression of C. elegans GLY-20 and bovine beta1,4-galactosyltransferase I in a baculoviral insect cell system results in efficient glycosylation of mammalian proteins.
Predicted to enable alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity. Involved in protein N-linked glycosylation. Predicted to be located in Golgi membrane. Used to study carbohydrate metabolic disorder. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIa. Is an ortholog of human MGAT2 (alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.