WormBase Tree Display for Gene: WBGene00000592

WBGene00000592 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: F08H9
  Identity: Version: 1
    Name: CGC_name: coh-3
      Sequence_name: F08H9.1
      Molecular_name: F08H9.1
        F08H9.1.1
        CE35852
      Other_name: CELE_F08H9.1 Accession_evidence: NDB BX284605
      Public_name: coh-3
    DB_info: Database: AceView gene 5O939
        WormQTL gene WBGene00000592
        WormFlux gene WBGene00000592
        NDB locus_tag CELE_F08H9.1
        NCBI gene 179949
        RefSeq protein NM_074182.3
        TREEFAM TREEFAM_ID TF322271
        TrEMBL UniProtAcc Q19232
        UniProt_GCRP UniProtAcc Q19232
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:21 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: coh
    Allele (53)
    Legacy_information: [J. Loidl] no RNAi phenotype found. Name assigned on the basis of sequence homology
      (F08H9.1) is homolog to the Rad21/Scc1/Rec8 family of cohesion proteins with known members in C. elegans, S. cerevisiae, S. pombe, A. thaliana and vertebrates. R-S-R is the acronym of the founder family
    Strain: WBStrain00035161
      WBStrain00035162
      WBStrain00035163
      WBStrain00035164
      WBStrain00035528
      WBStrain00055740
    RNASeq_FPKM (74)
    GO_annotation: 00063986
    Ortholog (20)
    Paralog: WBGene00021560 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
    Structured_description: Concise_description: coh-3 encodes a member of the Rad21/Rec8-like family of cohesion proteins known as kleisins; COH-3, along with its paralogs REC-8 and COH-4, function as members of a meiotic cohesin complex that mediates sister chromatid cohesion; coh-3 transcripts are expressed in the germline. Paper_evidence: WBPaper00004722
            WBPaper00005330
            WBPaper00005486
            WBPaper00005654
            WBPaper00034684
          Curator_confirmed: WBPerson48
            WBPerson1843
          Date_last_updated: 29 Nov 2010 00:00:00
      Automated_description: Involved in meiotic sister chromatid cohesion. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info (5)
  Experimental_info: RNAi_result (15)
    Expr_pattern: Expr11960
      Expr1027870
      Expr1030347
      Expr1148024
      Expr2010298
      Expr2028540
    Drives_construct: WBCnstr00037442
    Construct_product: WBCnstr00037442
    Antibody: WBAntibody00002562
      WBAntibody00002687
    Microarray_results (19)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032097:CGH-1-associated-mRNA
      WBPaper00032425:up_in_lin-35
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00035269:cde-1_regulated
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:germline-precursors_embryo_enriched
      WBPaper00037950:germline-precursors_embryo_SelectivelyEnriched
      WBPaper00037950:hypodermis_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038168:lin-35_upregulated
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00042194:nhr-114(RNAi)_upregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044760:germline_specific
      WBPaper00045050:csr-1(hypomorph)_downregulated
      WBPaper00045050:drh-3 (ne4253)_downregulated
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045521:Gender_Neutral
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046509:lin-35(n745)_upregulated
      WBPaper00047132:skn-1(RNAi)_downregulated_glp-1(ts)-dependent
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_8
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00050080:rbr-2(tm3141)_downregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050522:mafr-1(tm6082)_downregulated
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00051039:germline_enriched
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053295:lin-22(icb38)_downregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:PGCs_enriched_NuGen
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
      WBPaper00053606:N2_vs_elt-2(ca15)_upregulated
      WBPaper00053814:25C_downregulated_PY79
      WBPaper00055354:eat-2(ad1116)_upregulated
      WBPaper00055354:Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Metformin_upregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056443:DietaryRestriction_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056826:hmc_biased
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00059175:hlh-17p-XBP-1_downregulated
      WBPaper00059356:set-6(ok2195)_baz-2(tm0235)_regulated
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060886:spr-5(by101);met-2(n4256)_upregulated
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061340:Germline
      WBPaper00061527:T22D1.5-inx-14
      WBPaper00061530:nhr-49(e2144)_downregulated
      WBPaper00061753:csr-1(tor159)_downregulated_25C
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062056:dpl-1(n2994)_upregulated
      WBPaper00062056:lin-35(n745)_upregulated
      WBPaper00062056:lin-36(we36)_upregulated
      WBPaper00062146:MOG-7-degron_1h_regulated
      WBPaper00062146:MOG-7-degron_2h_regulated
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00063924:PARG-1_interacting
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_1
      WBPaper00025032:cluster_1
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_B
      WBPaper00040963:TA300_down
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00048637:lin-35(n745)_starvation_upregulated
      [cgc5767]:cluster_1
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MD_pd(53_min)
      [cgc5767]:expression_class_SM
      [cgc5767]:expression_class_SMD
      [cgc6390]:Cluster_E
      [cgc6390]:intrinsic
    Interaction (28)
  Map_info: Map: V Position: 6.41169 Error: 0.006664
    Positive: Positive_clone: F08H9 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 4170
        4233
    Pseudo_map_position
  Reference (22)
  Remark: Sequence connection from [Loidl J]
    Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene