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WormBase Tree Display for Gene: WBGene00020921

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Name Class

WBGene00020921SMapS_parentSequenceW01C8
IdentityVersion1
NameSequence_nameW01C8.5
Molecular_nameW01C8.5a
W01C8.5a.1
CE26751
W01C8.5b
CE41163
W01C8.5b.1
Other_nameXG314Accession_evidenceEMBLAF326938
CELE_W01C8.5Accession_evidenceNDBBX284606
Public_nameW01C8.5
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:03WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (43)
RNASeq_FPKM (74)
GO_annotation00010201
Ortholog (35)
ParalogWBGene00010345Caenorhabditis elegansFrom_analysisPanther
WBGene00010368Caenorhabditis elegansFrom_analysisTreeFam
Panther
Structured_descriptionAutomated_descriptionEnriched in several structures, including ABalaappppa; excretory gland cell; hyp3; neurons; and pharyngeal cell based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; skn-1; and hsf-1 based on microarray and RNA-seq studies. Is affected by seventeen chemicals including 1-methylnicotinamide; D-glucose; and Zidovudine based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); autoimmune disease (multiple); and kidney failure (multiple). Is predicted to encode a protein with the following domains: DM13 domain and Electron transfer DM13. Is an ortholog of human THBD (thrombomodulin).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:13809Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:8778Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:2945Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:676Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:9744Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:2841Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:9352Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:0111908Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:11247Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:0050156Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:8577Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:1875Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:0112313Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:7148Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:9074Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:10763Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:1459Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:409Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:3410Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:12132Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:9970Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:6432Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:0080301Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:3908Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:10223Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:7147Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:3526Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:783Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:2987Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:3021Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
DOID:3393Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:11784)
Molecular_infoCorresponding_CDSW01C8.5a
W01C8.5b
Corresponding_CDS_historyW01C8.5:wp176
Corresponding_transcriptW01C8.5a.1
W01C8.5b.1
Other_sequenceHBC04155_1
CRC03045_1
CJC02989_1
EX010178.1
Associated_feature (11)
Experimental_infoRNAi_resultWBRNAi00033350Inferred_automaticallyRNAi_primary
WBRNAi00054514Inferred_automaticallyRNAi_primary
WBRNAi00019460Inferred_automaticallyRNAi_primary
WBRNAi00054515Inferred_automaticallyRNAi_primary
Expr_patternExpr1024215
Expr1039116
Expr1158061
Expr2006665
Expr2024882
Drives_constructWBCnstr00024785
Construct_productWBCnstr00024785
Microarray_results (23)
Expression_clusterWBPaper00030922:glycosylated_protein
WBPaper00031040:Cluster_5
WBPaper00031040:TGF-beta_adult_upregulated
WBPaper00032976:dosage_compensated_genes
WBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00036375:enriched_in_PVD_OLL
WBPaper00037682:sma-2_sma-4_upregulated
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
WBPaper00044260:1-methylnicotinamide_downregulated
WBPaper00044260:nicotic-acid_downregulated
WBPaper00044736:flat_dev_expression
WBPaper00045417:128Q-huntingtin_downreglated
WBPaper00045521:Gender_Neutral
WBPaper00046024:sleep_downregulated_oscillating
WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
WBPaper00046805:csr-1(RNAi)_downregulated_Set1
WBPaper00048988:neuron_expressed
WBPaper00049495:starvation-refeeding_regulated
WBPaper00049498:npr-1(ur89)_regulated_3
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
WBPaper00049942:hsf-1(RNAi)_upregulated
WBPaper00050332:skn-1(RNAi)_downregulated
WBPaper00050488:20C_vs_25C_regulated_N2_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050990:body-muscle_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00051039:intestine_enriched
WBPaper00051352:Long-Term-Association-Memory_upregulated
WBPaper00051388:Glucose-diet_upregulated
WBPaper00051558:aging_regulated
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053295:lin-22(ot267)_upregulated
WBPaper00053295:lin-22(ot269)_upregulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053321:lin-15B(RNAi)_downregulated_starved-L1_Truseq
WBPaper00053321:PGCs_depleted_NuGen
WBPaper00053388:dauer_regulated_Cluster3
WBPaper00053599:oocyte_vs_mitosis_downregulated
WBPaper00054758:alg-1(gk204)_upregulated
WBPaper00055060:flr-1(RNAi)_upregulated
WBPaper00055354:Psora-Allantoin_upregulated
WBPaper00055354:Rapamycin_downregulated
WBPaper00055354:Rifampicin-Allantoin_upregulated
WBPaper00055354:Rifampicin_upregulated
WBPaper00055482:pmt-2(RNAi)_upregulated
WBPaper00055971:nhl-2(ok818)_20C_downregulated
WBPaper00055981:fog-2(q71)_downregulated
WBPaper00056034:pals-22(jy3)_upregulated
WBPaper00056039:ptl-1(ok621)_upregulated
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056275:P.aeruginosa_downregulated
WBPaper00056275:P.aeruginosa_downregulated_atf-7(qd22qd130)_dependent
WBPaper00056275:P.aeruginosa_downregulated_pmk-1(km25)_dependent
WBPaper00056284:ints-11(RNAi)_downregulated
WBPaper00056443:DietaryRestriction_upregulated
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056826:SGP_biased
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057006:DietaryRestriction_downregulated
WBPaper00057041:spc-1(cas971)_upregulated
WBPaper00057041:unc-70(cas983)_upregulated
WBPaper00057154:HeatShock_downregulated_miRNA-target
WBPaper00057154:HeatShock_upregulated_mRNA
WBPaper00057288:iff-1(RNAi)_downregulated_transcript
WBPaper00057347:nhr-14(tm1473)_upreglated
WBPaper00058711:paraquat_downregulated
WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
WBPaper00059895:wounding_upregulated
WBPaper00060661:sensory-neuron_enriched
WBPaper00060683:hlh-11(overexpression)_downregulated
WBPaper00060811:L1_vs_adult_downregulated_neural
WBPaper00060871:M.humicola-extract_1h_regulated
WBPaper00060871:M.humicola-infection_48h_regulated
WBPaper00060909:atfs-1(cmh15)_downregulated
WBPaper00060911:prx-5(RNAi)_upregulated_mRNA
WBPaper00061203:let-418(n3536)_upregulated
WBPaper00061203:sin-3(tm1276)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:BAG
WBPaper00061340:DA
WBPaper00061340:DB
WBPaper00061340:DD
WBPaper00061340:Excretory_gland
WBPaper00061340:g2
WBPaper00061340:g2_parent
WBPaper00061340:hyp3
WBPaper00061340:I2_grandparent
WBPaper00061340:I5
WBPaper00061340:IL1_parent
WBPaper00061340:M4_parent
WBPaper00061340:MC
WBPaper00061340:mc1
WBPaper00061340:Parent_of_g1P_I3
WBPaper00061340:Parent_of_MI_pm1DR
WBPaper00061340:Parent_of_PVP_and_rect_V
WBPaper00061340:Pharyngeal_neuron
WBPaper00061340:pm1_pm2
WBPaper00061340:RID
WBPaper00061340:RID_parent
WBPaper00061340:RIM_parent
WBPaper00061340:RIS
WBPaper00061340:RMD
WBPaper00061340:RME
WBPaper00061340:RMED
WBPaper00061479:hda-1(ne4748)_upregulated
WBPaper00061527:ldb-1_2877-scd-1_3086
WBPaper00061651:PVT_enriched
WBPaper00061823:mex-3(spr9)_downregulated
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062193:hsf-1(RNAi)_downregulated
WBPaper00062193:skn-1(RNAi)_downregulated
WBPaper00062345:bortezomib_4h_downregulated_N2
WBPaper00062446:nhr-8(hd117)_upregulated
WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated
WBPaper00064005:starvation_downregulated_N2_mRNA
WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064306:Agaro-oligosaccharides_upregulated
WBPaper00064727:daf-2(e1370)_upregulated
WBPaper00064871:hypoxia_downregulated_F2
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065120:body-muscle-transcriptome
WBPaper00065158:25C_vs_15C_upregulated_WholeAnimal
WBPaper00065749:endu-2(tm4977)_upregulated
WBPaper00065841:34_0
WBPaper00065841:34_1
WBPaper00066085:sin-3(tm1276)_upregulated
WBPaper00066110:tetraploid_vs_diploid_upregulated
cgc4386_cluster_6_3
cgc4489_group_6
WBPaper00025032:cluster_37
WBPaper00025032:cluster_44
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026980:intestine_enriched
WBPaper00028789:PA14_vs_OP50_downregulated_4hr
WBPaper00028789:PA14_vs_OP50_downregulated_8hr
WBPaper00029437:dcr-1_upregulated
WBPaper00030985:Erwinia_carotovora_upregulated
WBPaper00031003:0hr_muscle_depleted
WBPaper00031003:24hr_muscle_depleted
WBPaper00031003:hlh_1_enriched
WBPaper00031003:total_muscle_depleted
WBPaper00031252:AIN-2_IP_enriched
WBPaper00034739:N2lessDR1350
WBPaper00034757:down_by_oxidative_stress
WBPaper00035084:L1_enriched_AIN-2_IP
WBPaper00035905:FBF-1_Associated
WBPaper00036130:mir-243_up_regulated
WBPaper00036286:Pattern_G
WBPaper00036464:S.aureus-RN6390_regulated
WBPaper00040426:CYD-1_CDK-4_downregulated
WBPaper00040858:eQTL_age_regulated_developing
WBPaper00040963:Q100_down
WBPaper00040963:Q200_down
WBPaper00040985:AIN-2_asynchronous_intestine
WBPaper00040985:AIN-2_L4_intestine
WBPaper00041002:HF_3d_2.0mM_Up
WBPaper00041002:HF_11d_0.2mM_Up
WBPaper00041174:environmental
WBPaper00041174:genotypic
WBPaper00041174:genotypic_and_environmental
WBPaper00041267:SpaceFlight_Downregulated
WBPaper00041606:CE_S.marcescens_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041960:N2_fasting_upregulated_anytime
WBPaper00042234:xpa-1_upregulated
WBPaper00045263:0.1mM-paraquat_upregulated
WBPaper00045673:colistin_upregulated
WBPaper00045960:L4-lethargus_downregulated
WBPaper00046548:dafachronic-acid_upregulated
WBPaper00047070:N2_starvation_downregulated
WBPaper00048989:N2_rapamycin_upregulated
WBPaper00050767:Octopamine_induced
WBPaper00055899:nitroguanidine_regulated
WBPaper00057098:SiO2-nanoparticles_upregulated
[cgc5767]:expression_class_E
[cgc5767]:expression_class_E_pi(143_min)
[cgc5767]:expression_class_SE
[cgc5767]:expression_class_SE_pi(143_min)
[cgc6390]:Cluster_B
InteractionWBInteraction000139055
WBInteraction000294151
WBInteraction000566449
WBInteraction000566728
Map_infoPositivePositive_cloneW01C8Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionX-4.39653
MethodGene