WormBase Tree Display for Gene: WBGene00008631

WBGene00008631 SMap: S_parent: Sequence: F10A3
  Identity: Version: 2
    Name: CGC_name: clc-32 Person_evidence: WBPerson260
      Sequence_name: F10A3.1
      Molecular_name (3)
      Other_name: CELE_F10A3.1 Accession_evidence: NDB BX284605
      Public_name: clc-32
    DB_info: Database: AceView gene 5Q620
        WormQTL gene WBGene00008631
        WormFlux gene WBGene00008631
        NDB locus_tag CELE_F10A3.1
        Panther gene CAEEL|WormBase=WBGene00008631|UniProtKB=O45334
          family PTHR34151
        NCBI gene 184272
        RefSeq protein NM_074663.4
        TREEFAM TREEFAM_ID TF322214
        TrEMBL UniProtAcc O45334
        UniProt_GCRP UniProtAcc O45334
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:49 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 26 Jan 2024 23:28:21 WBPerson51134 Name_change: CGC_name: clc-32
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: clc
    Allele (41)
    Strain: WBStrain00032866
    RNASeq_FPKM (74)
    GO_annotation: 00034257
    Ortholog (14)
    Paralog: WBGene00020760 Caenorhabditis elegans From_analysis: TreeFam
            Panther
      WBGene00009710 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00009914 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00009907 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00012081 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00017871 Caenorhabditis elegans From_analysis: TreeFam
            Panther
      WBGene00044801 Caenorhabditis elegans From_analysis: TreeFam
            Panther
      WBGene00206468 Caenorhabditis elegans From_analysis: TreeFam
            Panther
      WBGene00044802 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00206477 Caenorhabditis elegans From_analysis: TreeFam
      WBGene00044681 Caenorhabditis elegans From_analysis: TreeFam
            Panther
      WBGene00018253 Caenorhabditis elegans From_analysis: TreeFam
            Panther
      WBGene00021340 Caenorhabditis elegans From_analysis: Panther
      WBGene00021336 Caenorhabditis elegans From_analysis: Panther
      WBGene00017153 Caenorhabditis elegans From_analysis: Panther
      WBGene00021339 Caenorhabditis elegans From_analysis: Panther
      WBGene00021337 Caenorhabditis elegans From_analysis: Panther
      WBGene00189956 Caenorhabditis elegans From_analysis: Panther
      WBGene00011140 Caenorhabditis elegans From_analysis: Panther
      WBGene00194894 Caenorhabditis elegans From_analysis: Panther
    Structured_description: Concise_description: F10A3.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; F10A3.1 is worm-specific, with obvious homologs only in C. elegans; F10A3.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. Paper_evidence: WBPaper00004961
            WBPaper00005654
            WBPaper00005946
            WBPaper00005975
            WBPaper00012856
            WBPaper00018356
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to be located in membrane. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F10A3.1
    Corresponding_transcript: F10A3.1.1
    Associated_feature: WBsf653477
      WBsf235120
  Experimental_info: RNAi_result: WBRNAi00030738 Inferred_automatically: RNAi_primary
      WBRNAi00044195 Inferred_automatically: RNAi_primary
      WBRNAi00013022 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1014317
      Expr1148151
      Expr2002370
      Expr2020588
    Drives_construct: WBCnstr00032815
    Construct_product: WBCnstr00032815
    Microarray_results (14)
    Expression_cluster: WBPaper00037950:AVA-neuron_embryo_enriched
      WBPaper00037950:AVA-neuron_embryo_SelectivelyEnriched
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_larva_enriched
      WBPaper00037950:bodywall-muscle_larva_SelectivelyEnriched
      WBPaper00037950:intestine_larva_enriched
      WBPaper00037950:intestine_larva_SelectivelyEnriched
      WBPaper00038168:lin-15B(n744)_upregulated
      WBPaper00038168:lin-35_upregulated
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00042477:prp-8(RNAi)_upregulated_RNAseq
      WBPaper00042477:rsr-2(RNAi)_upregulated_TilingArray
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044030:nhr-8(hd117)_upregulated
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
      WBPaper00049498:npr-1(ur89)_regulated_7
      WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
      WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050193:cec-4(ok3124)_downregulated_L1
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050504:hrp-2(RNAi)_upregulated
      WBPaper00053888:drh-3(rrr2)_upregulated
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00055013:spt-16(RNAi)_upregulated
      WBPaper00055137:S.maltophilia_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Psora_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
      WBPaper00055944:C.butyricum_vs_OP50_downregulated
      WBPaper00055971:nhl-2(ok818)_20C_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056039:efa-6(tm3124)_downregulated
      WBPaper00056039:hda-6(ok3203)_upregulated
      WBPaper00056167:Cry5B_downregulated
      WBPaper00056167:ifo-1(kc2)_downregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay4
      WBPaper00056809:smn-1(ok355)_upregulated
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00057068:Cadmium_upregulated
      WBPaper00057068:ints-4(RNAi)_upregulated
      WBPaper00057068:ints-4(RNAi)_upregulated_Cadmium
      WBPaper00057265:metaformin_downregulated_OP50
      WBPaper00057265:metaformin_downregulated_OP50-MR
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00058725:sftb-1(cer39)_upregulated
      WBPaper00058948:npr-8(ok1439)_upregulated_PA14
      WBPaper00058948:PA14_downregulated
      WBPaper00059334:sacy-1(depletion)_regulated
      WBPaper00059527:lsm-1_upregulated_L1
      WBPaper00059735:glucose_downregulated_lpin-1(RNAi)
      WBPaper00059987:Wounding_upregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060921:cat-2(e1112)_downregulated
      WBPaper00060921:tdc-1(n3419)_downregulated
      WBPaper00060921:tph-1(mg280)_downregulated
      WBPaper00061040:eat-2(ad1116)_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061527:ckr-1-T09B9.3
      WBPaper00061530:nhr-49(e2144)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_upregulated_N2
      WBPaper00062345:bortezomib_4h_upregulated_zip-1(jy13)
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062497:xpf-1(tm2842)_upregulated
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064505:tamoxifen_upregulated
      WBPaper00064509:static-magnetic-field_upregulated
      WBPaper00064539:nhr-114(gk849)_upregulated
      WBPaper00064661:lpd-3(ok2138)_upregulated
      WBPaper00065029:cadmium_upregulated
      WBPaper00065086:N2_N.ausubeli_regulated
      WBPaper00065749:Heat-Shock-With-Recovery_upregulated_N2
      WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose
      WBPaper00065984:pals-17(syb3980)_upregulated
      WBPaper00066204:CdCl2_upregulated_mRNA
      WBPaper00066232:hsf-1(RNAi)_upregulated_WT
      cgc4489_group_2
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026980:intestine_enriched
      WBPaper00027111:rrf-1(pk1417)_upregulated
      WBPaper00035227:heat_shock_regulated
      WBPaper00036123:Atrazine_regulated
      WBPaper00036286:Pattern_D
      WBPaper00037695:WC_5-day
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00041002:HF_11d_0.2mM_Up
      WBPaper00041002:HQ_3d_0.2mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00046548:dafachronic-acid_downregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00048989:eat-2(ad465)_upregulated_in-DMSO
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00050520:lagr-1(gk327);hyl-1(ok976)_upregulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
    Interaction (55)
  Map_info: Map: V Position: 9.79539
    Positive: Positive_clone: F10A3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00037416
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene