WormBase Tree Display for Gene: WBGene00009710

WBGene00009710 SMap: S_parent: Sequence: F44G3
  Identity: Version: 2
    Name: CGC_name: clc-11 Person_evidence: WBPerson260
      Sequence_name: F44G3.10
      Molecular_name: F44G3.10
        F44G3.10.1
        CE16041
      Other_name: CELE_F44G3.10 Accession_evidence: NDB BX284605
      Public_name: clc-11
    DB_info: Database: AceView gene 5Q618
        WormQTL gene WBGene00009710
        WormFlux gene WBGene00009710
        NDB locus_tag CELE_F44G3.10
        Panther gene CAEEL|WormBase=WBGene00009710|UniProtKB=O45515
          family PTHR34151
        NCBI gene 185758
        RefSeq protein NM_074662.5
        TREEFAM TREEFAM_ID TF322214
        TrEMBL UniProtAcc O45515
        UniProt_GCRP UniProtAcc O45515
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:50 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 26 Jan 2024 23:28:21 WBPerson51134 Name_change: CGC_name: clc-11
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: clc
    Allele (69)
    Strain: WBStrain00032852
    RNASeq_FPKM (74)
    GO_annotation: 00034672
      00034673
    Ortholog (15)
    Paralog (20)
    Structured_description: Concise_description: F44G3.10 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; F44G3.10 is worm-specific, with obvious homologs only in C. elegans; F44G3.10 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water. Paper_evidence: WBPaper00004961
            WBPaper00005654
            WBPaper00005946
            WBPaper00005975
            WBPaper00012856
            WBPaper00018356
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Involved in innate immune response. Predicted to be located in membrane. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F44G3.10
    Corresponding_transcript: F44G3.10.1
    Associated_feature: WBsf653476
      WBsf1002403
      WBsf235119
  Experimental_info: RNAi_result: WBRNAi00014961 Inferred_automatically: RNAi_primary
      WBRNAi00032263 Inferred_automatically: RNAi_primary
      WBRNAi00047329 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1017616
      Expr1151180
      Expr2003732
      Expr2021952
    Drives_construct: WBCnstr00031976
    Construct_product: WBCnstr00031976
    Microarray_results (14)
    Expression_cluster (260)
    Interaction: WBInteraction000124597
      WBInteraction000245142
      WBInteraction000386321
      WBInteraction000546932
  Map_info: Map: V Position: 9.79454
    Positive: Positive_clone: F44G3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene