WormBase Tree Display for Gene: WBGene00008921

WBGene00008921 SMap: S_parent: Sequence: F17C11
  Identity: Version: 2
    Name: CGC_name: ctf-4 Person_evidence: WBPerson30546
      Sequence_name: F17C11.10
      Molecular_name: F17C11.10
        F17C11.10.1
        CE05657
      Other_name: CELE_F17C11.10 Accession_evidence: NDB BX284605
      Public_name: ctf-4
    DB_info: Database: AceView gene 5L442
        WormQTL gene WBGene00008921
        WormFlux gene WBGene00008921
        NDB locus_tag CELE_F17C11.10
        Panther gene CAEEL|WormBase=WBGene00008921|UniProtKB=Q19520
          family PTHR19932
        NCBI gene 179521
        RefSeq protein NM_073398.5
        TREEFAM TREEFAM_ID TF105988
        TrEMBL UniProtAcc Q19520
        UniProt_GCRP UniProtAcc Q19520
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:49 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 05 Apr 2017 11:17:23 WBPerson2970 Name_change: CGC_name: ctf-4
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ctf
    Allele (49)
    RNASeq_FPKM (74)
    GO_annotation: 00064969
      00064970
      00064971
      00064972
      00064973
      00064974
      00064975
      00064976
    Contained_in_operon: CEOP5268
    Ortholog: WBGene00041490 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00066253 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00157762 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00132245 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00099930 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00223683 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g965 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g812 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g482 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g892 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g17921 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g10555 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g4688 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g21470 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g3487 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g1589 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00253.g7932 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-F17C11.10 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold71.g441 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00065.g3089 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_23890 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_016539 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g02046 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g2488 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_50305800 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrV_pilon.g15655 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00243610 Onchocerca volvulus From_analysis: WormBase-Compara
      WBGene00261105 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00291120 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000006339 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Hieranoid
            OrthoFinder
            Panther
      FB:FBgn0033890 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      ZFIN:ZDB-GENE-030131-1665 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:23170 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:2443514 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1310200 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Structured_description: Automated_description: Predicted to enable chromatin binding activity. Predicted to be involved in DNA repair; DNA-templated DNA replication; and mitotic cell cycle. Predicted to be located in nuclear replication fork. Predicted to be part of replication fork protection complex. Human ortholog(s) of this gene implicated in cholangiocarcinoma. Is an ortholog of human WDHD1 (WD repeat and HMG-box DNA binding protein 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:4947 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:23170)
  Molecular_info: Corresponding_CDS: F17C11.10
    Corresponding_transcript: F17C11.10.1
    Other_sequence: CR00891
      CR04214
      CJC12789_1
      CJC13735_1
      CRC02477_1
      CRC12170_1
      CR00103
      CBC13226_1
    Associated_feature: WBsf653052
      WBsf234475
      WBsf234476
  Experimental_info: RNAi_result: WBRNAi00013456 Inferred_automatically: RNAi_primary
      WBRNAi00108113 Inferred_automatically: RNAi_primary
      WBRNAi00007584 Inferred_automatically: RNAi_primary
      WBRNAi00094296 Inferred_automatically: RNAi_primary
      WBRNAi00108114 Inferred_automatically: RNAi_primary
      WBRNAi00044871 Inferred_automatically: RNAi_primary
      WBRNAi00108126 Inferred_automatically: RNAi_primary
      WBRNAi00094214 Inferred_automatically: RNAi_primary
      WBRNAi00108115 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1027543
      Expr1033883
      Expr1148835
      Expr2010570
      Expr2028810
    Drives_construct: WBCnstr00032593
    Construct_product: WBCnstr00032593
    Antibody: WBAntibody00002991
    Microarray_results (20)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032031:DConiospora_upregulated_cDNA_24h
      WBPaper00032031:DConiospora_upregulated_OligoArray_24h
      WBPaper00032425:up_in_lin-35
      WBPaper00033065:isp-1-1(qm150)_upregulated
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00038168:lin-35_upregulated
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00041071:spe-44_upregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044760:germline_specific
      WBPaper00045050:drh-3 (ne4253)_downregulated
      WBPaper00045521:Oogenic
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_upregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046509:lin-35(n745)_upregulated
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048690:hermaphrodite-Z1-Z4-daughter_enriched
      WBPaper00048690:male-Z1-Z4-daughter_enriched
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049159:Microwave_upregulated_adult
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_downregulated_N2
      WBPaper00049942:HeatShock_downregulated_hsf-1(+)
      WBPaper00049942:HeatShock_upregulated_hsf-1(RNAi)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00049954:BPS_downregulated
      WBPaper00050193:cec-4(ok3124)_downregulated_L1
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050522:mafr-1(tm6082)_downregulated
      WBPaper00050686:glp-1(e2141)_downregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050743:elli-1(sam-3)_upregulated
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051265:F4_morc-1(tm6048)_upregulated
      WBPaper00051461:pig-1(gm344)_upregulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053599:female_vs_male_upregulated
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_upregulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_downregulated
      WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055565:AVK_enriched
      WBPaper00055648:germline_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055897:heat-shock_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056275:P.aeruginosa_upregulated_atf-7(qd22qd130)_dependent
      WBPaper00056275:P.aeruginosa_upregulated_pmk-1(km25)_dependent
      WBPaper00056284:ints-5(RNAi)_downregulated
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056826:hmc_biased
      WBPaper00057154:HeatShock_downregulated_mRNA
      WBPaper00057154:HeatShock_upregulated_miRNA-target
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00058598:mex-3(eu149)_downregulated
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058691:WDR-5.1_interacting_protein
      WBPaper00059027:neuron-synapses_enriched
      WBPaper00059174:MEG-3_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061203:spr-1(ok2144)_downregulated
      WBPaper00061340:ADA_ADE_grandparent
      WBPaper00061340:Ciliated_amphid_neuron
      WBPaper00061340:Neuroblast_ASE_ASJ_AUA
      WBPaper00061340:Neuroblast_BAG_SMDVx
      WBPaper00061340:Parent_of_AMsh_URB
      WBPaper00061340:PLM_ALN_great_grandparent
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061479:HDA-1_interacting_protein
      WBPaper00061527:pch-2-B0393.3
      WBPaper00061699:daf-18(ok480)_upregulated
      WBPaper00062056:dpl-1(n2994)_upregulated
      WBPaper00062056:efl-1(se1)_upregulated
      WBPaper00062056:lin-35(n745)_upregulated
      WBPaper00062056:lin-36(n766)_upregulated
      WBPaper00062056:lin-36(we31)_upregulated
      WBPaper00062056:lin-36(we36)_upregulated
      WBPaper00062143:PQN-59_interacting
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062456:doxycycline_downregulated_CB4856_protein
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064201:SNA-3_interacting
      WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
      WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
      WBPaper00064505:tamoxifen_upregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065149:lin-52(n771)_upregulated
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065841:3_0
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4386_cluster_5_1
      cgc4489_group_2
      WBPaper00025099:NI_specific
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00031060:2-deoxy-D-glucose_downregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036123:Cadmium_regulated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_B
      WBPaper00037901:GLD-1_mRNA_targets
      WBPaper00040426:CYD-1_CDK-4_upregulated
      WBPaper00040426:CYE-1_CDK-2AF_upregulated
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00042128:gei-8(ok1671)_downregulated
      WBPaper00042274:tbx-2(bx59)_downregulated
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00048637:lin-35(n745)_starvation_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00056330:mrps-5(RNAi)_downregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc6390]:Cluster_E
      [cgc6390]:oogenesis-enriched
    Interaction (129)
  Map_info: Positive: Positive_clone: F17C11 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: V 2.85487
  Reference: WBPaper00038491
    WBPaper00055090
    WBPaper00066002
  Method: Gene