WormBase Tree Display for Gene: WBGene00008707

WBGene00008707 SMap: S_parent: Sequence: F11E6
  Identity: Version: 2
    Name: CGC_name: epic-1 Person_evidence: WBPerson105
      Sequence_name: F11E6.3
      Molecular_name: F11E6.3
        F11E6.3.1
        CE19783
      Other_name: CELE_F11E6.3 Accession_evidence: NDB BX284604
      Public_name: epic-1
    DB_info: Database: AceView gene 4S414
        WormQTL gene WBGene00008707
        WormFlux gene WBGene00008707
        NDB locus_tag CELE_F11E6.3
        Panther gene CAEEL|WormBase=WBGene00008707|UniProtKB=Q9U3J8
          family PTHR36514
        NCBI gene 178533
        RefSeq protein NM_070715.9
        TREEFAM TREEFAM_ID TF322540
        TrEMBL UniProtAcc Q9U3J8
        UniProt_GCRP UniProtAcc Q9U3J8
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:49 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 27 Oct 2021 12:29:35 WBPerson1983 Name_change: CGC_name: epic-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: epic
    Allele (50)
    RNASeq_FPKM (74)
    Ortholog: WBGene00023824 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00069557 Caenorhabditis remanei From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00162061 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00091683 Pristionchus pacificus From_analysis: OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00125230 Caenorhabditis japonica From_analysis: Inparanoid_8
            WormBase-Compara
      CBOVI.g7962 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g12083 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP28.g4230 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g11393 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g26894 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g9328 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g3925 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g29207 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g7216 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00504.g11623 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cni-F11E6.3 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold70.g423 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00306.g9093 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_22901 Caenorhabditis latens From_analysis: WormBase-Compara
      FL83_22919 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_011953 Caenorhabditis remanei From_analysis: WormBase-Compara
      Pan_g15603 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_40217700 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrIV_pilon.g12918 Caenorhabditis elegans From_analysis: WormBase-Compara
    Paralog: WBGene00044293 Caenorhabditis elegans From_analysis: Panther
      WBGene00019540 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Enriched in several structures, including accessory cell; anterior hypodermis; germ line; rectal epithelial cell; and rectum based on tiling array; RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; tiling array; and RNA-seq studies. Is affected by twenty-five chemicals including diallyl trisulfide; nicotinic acid; and rotenone based on microarray and RNA-seq studies. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F11E6.3
    Corresponding_transcript: F11E6.3.1
    Other_sequence (16)
    Associated_feature: WBsf668599
      WBsf999044
      WBsf1018988
  Experimental_info: RNAi_result (7)
    Expr_pattern: Expr3612
      Expr1018748
      Expr1033792
      Expr1148339
      Expr2002454
      Expr2020670
    Drives_construct: WBCnstr00015935
    Construct_product: WBCnstr00011537
    Microarray_results (18)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032031:DConiospora_downregulated_OligoArray_24h
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00033444:BacteriaDiet_regulated
      WBPaper00035269:cde-1_regulated
      WBPaper00037950:CEP-sheath-cells_adult_enriched
      WBPaper00037950:CEP-sheath-cells_adult_SelectivelyEnriched
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038104:DATS_upregulated
      WBPaper00038237:age-1_upregulated_intestine_rescue
      WBPaper00038237:age-1_upregulated_neuron_rescue
      WBPaper00038237:age-1_upregulated_nontransgenic
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00040990:PA14_downregulated
      WBPaper00042215:wdr-23(tm1817)_downregulated
      WBPaper00042477:rsr-2(RNAi)_upregulated_RNAseq
      WBPaper00044037:eat-2_upregulated
      WBPaper00044260:nicotinc-acid_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044760:germline_specific
      WBPaper00045050:drh-3 (ne4253)_downregulated
      WBPaper00045316:prg-1_upregulated_L1
      WBPaper00045401:N.parisii_64h_downregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045774:clk-1_upregulated
      WBPaper00045934:wrn-1(gk99)_upregulated
      WBPaper00045974:NSM_enriched_totalRNA_RNAseq
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048971:daf-16(mgDf50)_downregulated_L1
      WBPaper00048988:daf-2(e1370)_daf-16(mu86)_upregulated_neuron
      WBPaper00048988:neuron_expressed
      WBPaper00049217:DAF-16_upregulated
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00049942:HeatShock_upregulated_hsf-1(+)
      WBPaper00049954:BPA_downregulated
      WBPaper00050080:rbr-2(tm3141)_downregulated
      WBPaper00050096:P.aeruginosa_downregulated
      WBPaper00050163:chd-3(eh4)_downregulated_24-cell-embryo
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050468:hlh-30-dependent_Cry5B_regulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050801:DAF-12_dauer_regulome
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050903:mir-35-41(nDf50)_25C_upregulated
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051265:F4_hrde-1(tm1200)_upregulated
      WBPaper00051265:F4_morc-1(tm6048)_downregulated
      WBPaper00051352:Long-Term-Association-Memory_downregulated
      WBPaper00051404:alg-1(gk214)_upregulated
      WBPaper00051404:alg-2(ok304)_upregulated
      WBPaper00051558:aging_regulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053318:Aging_downregulated_mRNA_N2
      WBPaper00053318:mir-71(n4115)_downregulated_mRNA
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053402:cco-1(RNAi)_upregulated
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053888:drh-3(rrr2)_downregulated
      WBPaper00054872:egl-9(sa307)_downregulated
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055013:hmg-4(RNAi)_upregulated
      WBPaper00055013:spt-16(RNAi)_upregulated
      WBPaper00055049:S.gordonii_downregulated
      WBPaper00055060:flr-1(RNAi)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Psora_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055482:Tunicamycin_downregulated
      WBPaper00055626:pry-1(mu38)_downregulated
      WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055969:electromagnetic-field_upregulated
      WBPaper00055971:nhl-2(ok818)_20C_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056034:pals-25(jy9)_downregulated
      WBPaper00056039:efa-6(tm3124)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056167:Cry5B_downregulated
      WBPaper00056169:rrf-3(pk1426)_upregulated_embryo
      WBPaper00056169:rrf-3(pk1426)_upregulated_L3
      WBPaper00056169:rrf-3(pk1426)_upregulated_L4
      WBPaper00056290:hsp-6(mg585)_downregulated
      WBPaper00056290:mdt-15(mg584)_downregulated
      WBPaper00056443:DietaryRestriction_downregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056868:P.aeruginosa_downregulated_smallRNA
      WBPaper00057068:ints-4(RNAi)_upregulated
      WBPaper00057068:numr-1(RNAi)_upregulated
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058711:paraquat_upregulated
      WBPaper00058711:wdr-5(ok1417)_upregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00058927:high-redox-state_downregulated
      WBPaper00058948:npr-8(ok1439)_downregulated_PA14
      WBPaper00058948:PA14_upregulated
      WBPaper00058958:100mGy-irradiation-72h_upregulated
      WBPaper00059194:klf-1(RNAi)_regulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059421:daf-1(m40);daf-3(mgDf90)_upregulated
      WBPaper00059566:wdr-23(mac32)_upregulated
      WBPaper00059567:olrn-1(ums9)_regulated
      WBPaper00059605:mut-16(pk710)_upregulated
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059728:5ug_cholesterol_upregulated
      WBPaper00059728:20ug_cholesterol_upregulated
      WBPaper00059735:glucose_upregulated_lpin-1(RNAi)
      WBPaper00059739:hira-1(gk835598)_upregulated_L4
      WBPaper00059895:wounding_downregulated
      WBPaper00059987:Wounding_downregulated
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060100:SiNP_upregulated_mRNA
      WBPaper00060278:atp-2(RNAi)_upregulated
      WBPaper00060358:B.thuringiensis_non-pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060683:hlh-11(overexpression)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060871:M.humicola-extract_1h_regulated
      WBPaper00061040:FW1256_upregulated
      WBPaper00061045:Y56A3A.22(cck200)_upregulated
      WBPaper00061081:E.faecalis_downregulated_skpo-1(ok1640)
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061274:hypergravity_15xg_upregulated
      WBPaper00061340:ADEsh
      WBPaper00061340:B_F_K_Kp_U_Y
      WBPaper00061340:F_U
      WBPaper00061340:GLR
      WBPaper00061340:hyp1_hyp2
      WBPaper00061340:K_Kprime
      WBPaper00061340:Rectal_cell
      WBPaper00061340:Rectal_gland
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061478:pie-1(ne4433)_upregulated
      WBPaper00061479:prg-1(tm872)_upregulated
      WBPaper00061479:ubc-9(ne4833)_upregulated
      WBPaper00061527:mup-2-unc-87_284
      WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_downregulated
      WBPaper00061651:AMso_enriched
      WBPaper00061651:PHsh_enriched
      WBPaper00061651:PHso_enriched
      WBPaper00061653:alh-4(hj221)_downregulated
      WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
      WBPaper00062118:neural-HSF-1_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062167:mbl-1(tm1563)_downregulated
      WBPaper00062193:daf-16(RNAi)_upregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062347:blmp-1(tm548)_upregulated
      WBPaper00062354:H.zoospora_6h_regulated
      WBPaper00062440:crh-1(n3315)_upregulated
      WBPaper00062440:crh-1(syb385)_upregulated
      WBPaper00062446:nhr-8(hd117)_downregulated
      WBPaper00062590:Aging_downregulated_neuron
      WBPaper00064005:starvation_downregulated_aptf-1(gk794)_mRNA
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064130:Beta-Amyloid_24h_upregulated_mRNA
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064735:bet-1B(OE)_vs_N2_upregulated
      WBPaper00064871:hypoxia_upregulated_F1
      WBPaper00064933:bcf-1(ylf1)_downregulated_transcript
      WBPaper00065029:cadmium_downregulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065086:N2_N.ferruginous_regulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065096:npr-8(ok1439)_downregulated_Day10_20C
      WBPaper00065096:npr-8(ok1439)_upregulated_Day1_25C
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:AFD_depleted
      WBPaper00065272:dhgd-1(tm6671)_downregulated
      WBPaper00065623:74
      WBPaper00065749:Heat-Shock_upregulated_endu-2(tm4977)
      WBPaper00065749:Heat-Shock_upregulated_N2
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
      WBPaper00065841:0_0
      WBPaper00065841:30_1
      WBPaper00065841:30_2
      WBPaper00065841:64_0
      WBPaper00065926:pgph-2(overepxreesion)_upregulated_glucose
      WBPaper00065945:epidermis-rpoa-2(-)_downregulated_transcript
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_1_5
      WBPaper00005124:cholesterol_10-9M_regulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00028789:PA14_vs_gacA_downregulated_8hr
      WBPaper00028789:PA14_vs_OP50_downregulated_8hr
      WBPaper00030985:Enterococcus_faecalis_downregulated
      WBPaper00030985:Photorhabdus_luminescens_downregulated
      WBPaper00031003:hlh_1_enriched
      WBPaper00031060:2-deoxy-D-glucose_upregulated
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00031252:AIN-2_IP_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00035084:embryo_enriched_AIN-2_IP
      WBPaper00035084:L1_enriched_AIN-2_IP
      WBPaper00035084:L2_enriched_AIN-2_IP
      WBPaper00035084:L4_enriched_AIN-2_IP
      WBPaper00036286:Pattern_C
      WBPaper00036464:S.aureus-RN6390_regulated
      WBPaper00038172:crh-1null_up_regulated
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00038462:aging_downregulated
      WBPaper00040821:Au-NP_regulated
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040963:Q50_up
      WBPaper00040963:Q100_up
      WBPaper00040963:Q200_up
      WBPaper00040985:AIN-2_asynchronous_intestine
      WBPaper00041002:HF_11d_0.2mM_Up
      WBPaper00041002:HF_11d_2.0mM_Up
      WBPaper00041002:HQ_3d_2.0mM_Down
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041906:I-3690_vs_OP50_3d
      WBPaper00041906:I-3690_vs_OP50_10d
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042258:DA1877_upregulated_GravidAdult
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00045015:nhr-25(RNAi)_downregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048624:hlh-25(ok1710)_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00053550:daf-19(m86)_downregulated_L1
      WBPaper00055899:nitroguanidine_regulated
      WBPaper00057098:SiO2-nanoparticles_downregulated
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(83_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
    Interaction (50)
  Map_info: Positive: Positive_clone: F11E6 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: IV 17.1265
  Reference: WBPaper00038491
    WBPaper00059997
    WBPaper00064676
    WBPaper00064942
    WBPaper00065331
  Method: Gene