WormBase Tree Display for Gene: WBGene00006784

WBGene00006784 Evidence: CGC_data_submission
  SMap: S_parent: Sequence: T21C12
  Identity: Version: 1
    Name: CGC_name: unc-49 Person_evidence: WBPerson261
      Sequence_name: T21C12.1
      Molecular_name (40)
      Other_name: unc-49A Accession_evidence: EMBL AF151640
        unc-49B Accession_evidence: EMBL AF151641
        unc-49C Accession_evidence: EMBL AF151644
        CELE_T21C12.1 Accession_evidence: NDB BX284603
      Public_name: unc-49
    DB_info: Database: AceView gene 3L621
        WormQTL gene WBGene00006784
        WormFlux gene WBGene00006784
        NDB locus_tag CELE_T21C12.1
        Panther gene CAEEL|WormBase=WBGene00006784|UniProtKB=G5ECD3
          family PTHR18945
        NCBI gene 176472
        RefSeq protein (13)
        TrEMBL UniProtAcc (13)
        UniProt_GCRP UniProtAcc G5ECD3
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:42 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info (12)
  Disease_info: Experimental_model: DOID:1826 Homo sapiens Paper_evidence: WBPaper00060194
          Curator_confirmed: WBPerson324
          Date_last_updated: 18 May 2022 00:00:00
  Models_disease_asserted: WBDOannot00001202
    WBDOannot00001203
  Molecular_info: Corresponding_CDS (13)
    Corresponding_CDS_history: T21C12.1a:wp227
      T21C12.1a:wp239
      T21C12.1g:wp275
    Corresponding_transcript (14)
    Other_sequence (51)
    Associated_feature (25)
  Experimental_info: RNAi_result (10)
    Expr_pattern: Expr1283
      Expr15907
      Expr1027570
      Expr1032855
      Expr1157259
      Expr1200291
      Expr2017881
      Expr2036017
      Marker2
      Marker19
    Drives_construct: WBCnstr00001626
      WBCnstr00001627
      WBCnstr00006881
      WBCnstr00010191
      WBCnstr00019381
      WBCnstr00020581
      WBCnstr00034153
      WBCnstr00042588
    Construct_product: WBCnstr00001627
      WBCnstr00006881
      WBCnstr00016180
      WBCnstr00019381
      WBCnstr00020010
      WBCnstr00020581
      WBCnstr00021428
      WBCnstr00034153
    Antibody: WBAntibody00000613
      WBAntibody00001987
    Microarray_results (88)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037055:DAF-16_binding_DNA
      WBPaper00037946:EGL-5_interacting
      WBPaper00038061:aldicarb_downregulated
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044037:eat-2_regulated_nhr-62_dependent
      WBPaper00044037:eat-2_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:flat_dev_expression
      WBPaper00044786:emr-1(gk119)_upregulated
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_upregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045774:clk-1_upregulated
      WBPaper00045861:ash-2(tm1095)_upregulated
      WBPaper00045861:set-2(ok952)_upregulated
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048988:neuron_enriched
      WBPaper00048988:neuron_expressed
      WBPaper00049626:UNC-75_target
      WBPaper00050015:ifg-1(RNAi)_upregulated
      WBPaper00050094:mes-2(bn11)_upregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:daf-2(e1370)_vs_daf-2(e1370);mir-34(gk437)_regulated_dauer_25C
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:alovudine_72h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_upregulated
      WBPaper00055354:Rifampicin_upregulated
      WBPaper00055482:Tunicamycin_downregulated
      WBPaper00055827:pfd-6(gk493446)_downregulated
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056161:hermaphrodite_enriched_siRNA
      WBPaper00056284:ints-11(RNAi)_downregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056586:kri-1(ok1251);mpk-2(ok219)_downregulated
      WBPaper00056586:kri-1(ok1251)_downregulated
      WBPaper00056586:mpk-2(ok219)_downregulated
      WBPaper00056826:hmc_biased
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057161:meg-3(tm4259)_meg-4(ax2026)_downregulated_endo-siRNA_targets
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058598:spn-4(tm291)_upregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00059027:neuron-synapses_depleted
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059754:P.aeruginosa_PA14_upregulated
      WBPaper00059763:neuron_expressed
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00060014:set-2(tm1630)_downregulated
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061340:BWM_far_posterior
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061466:nath-10(icb99)_upregulated
      WBPaper00061466:nath-10(icb102)_upregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061479:mep-1(ne4629)_upregulated
      WBPaper00061479:ubc-9(ne4833)_upregulated
      WBPaper00061527:176662_at-Y53F4B.16
      WBPaper00061527:myo-3-Y71G12B.11_22540
      WBPaper00061527:syd-1_2945-unc-41_2170
      WBPaper00061651:MI_enriched
      WBPaper00061651:VB01_enriched
      WBPaper00061995:mter-4(syb3662syb3403)_downregulated
      WBPaper00062103:neuron_enriched
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:etr-1(lq61)_downregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064122:vulva_transcriptome
      WBPaper00064156:lbp-3(overexpress)_upregulated
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065258:anchor-cell_depleted
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065835:Day5_vs_Day1_downregulated
      WBPaper00065835:Day11_vs_Day1_downregulated
      WBPaper00065841:4_0
      WBPaper00065841:6_0
      WBPaper00065841:6_2
      WBPaper00065841:10_0
      WBPaper00065841:38_2
      WBPaper00065841:51_0
      WBPaper00065841:51_1
      WBPaper00065841:76_0
      WBPaper00065841:98_0
      WBPaper00065841:102_0
      WBPaper00065841:103_0
      WBPaper00065841:115_0
      WBPaper00065841:133_0
      WBPaper00065841:136_0
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_3_3
      cgc4489_group_20
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00030839:Larval_Pan_Neuronal
      WBPaper00031003:0hr_muscle_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_enriched
      WBPaper00031252:AIN-2_IP_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00031832:slr-2_regulated
      WBPaper00034661:AgNPs_downregulated
      WBPaper00035084:L1_enriched_AIN-2_IP
      WBPaper00035084:L2_enriched_AIN-2_IP
      WBPaper00035084:L4_enriched_AIN-2_IP
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00036123:Atrazine_regulated
      WBPaper00038304:octr-1_regulated
      WBPaper00038427:lin-54_embryo_changed
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040876:mir-35_downregulated
      WBPaper00040963:TA300_up
      WBPaper00040985:AIN-2_asynchronous_muscle
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_prime
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042236:flcn-1(ok975)_upregulated
      WBPaper00042548:miRISC_enriched
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_upregulated
      WBPaper00047070:N2_UV_downregulated
      WBPaper00048989:N2_rapamycin_upregulated
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_SM
      [cgc6390]:Cluster_A
    Interaction (31)
    WBProcess: WBbiopr:00000010
  Map_info: Map: III Position: 3.35021 Error: 0.089636
    Well_ordered
    Positive: Inside_rearr: nDf40
        mT1
      Positive_clone: T21C12 Person_evidence: WBPerson39
          Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: 2_point: 73
        86
        589
        3249
      Multi_point: 60
        81
        85
        86
        87
        88
        89
        211
        212
        213
        214
        215
        216
        300
        301
        469
        471
        472
        473
        474
        476
        482
        483
        489
        493
        494
        497
        500
        501
        503
        504
        507
        514
        562
        563
        1246
        1253
        1356
        1811
        1814
        1819
        2196
        2202
        2203
        2204
        2205
        3217
        3223
        3224
        3235
        3237
        4097
        5025
        5626
        5710
      Pos_neg_data: 3242
        3250
        3251
  Reference (138)
  Remark: Sequence connection from [Bamber BA]
  Method: Gene