WormBase Tree Display for Gene: WBGene00013263

WBGene00013263 SMap: S_parent: Sequence: Y57A10A
  Identity: Version: 2
    Name: CGC_name: txdc-12.1 Person_evidence: WBPerson3772
            WBPerson38007
      Sequence_name: Y57A10A.23
      Molecular_name: Y57A10A.23
        Y57A10A.23.1
        CE22626
      Other_name: CELE_Y57A10A.23 Accession_evidence: NDB BX284602
      Public_name: txdc-12.1
    DB_info: Database: AceView gene 2M531
        WormQTL gene WBGene00013263
        WormFlux gene WBGene00013263
        NDB locus_tag CELE_Y57A10A.23
        Panther gene CAEEL|WormBase=WBGene00013263|UniProtKB=Q9NA78
          family PTHR15337
        NCBI gene 174863
        RefSeq protein NM_001383970.2
        TREEFAM TREEFAM_ID TF321449
        TrEMBL UniProtAcc Q9NA78
        UniProt_GCRP UniProtAcc Q9NA78
    Species: Caenorhabditis elegans
    History: Version_change: 1 26 May 2004 16:54:54 WBPerson1971 Event: Imported: Initial conversion from CDS class of WS125
        2 01 Aug 2017 12:58:54 WBPerson2970 Name_change: CGC_name: txdc-12.1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: txdc
    Allele (61)
    Strain: WBStrain00002731
    RNASeq_FPKM (74)
    GO_annotation: 00095844
    Ortholog (40)
    Paralog: WBGene00018656 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable oxidoreductase activity. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in breast cancer; pancreatic ductal adenocarcinoma; and pancreatic ductal carcinoma. Is an ortholog of human TXNDC12 (thioredoxin domain containing 12). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:3587 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:328)
      DOID:3498 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:328)
      DOID:1612 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:328)
  Molecular_info: Corresponding_CDS: Y57A10A.23
    Corresponding_transcript: Y57A10A.23.1
    Other_sequence (86)
    Associated_feature: WBsf222252
  Experimental_info: RNAi_result: WBRNAi00057625 Inferred_automatically: RNAi_primary
      WBRNAi00037562 Inferred_automatically: RNAi_primary
      WBRNAi00021100 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr7070
      Expr1022917
      Expr1035918
      Expr1161035
      Expr2008013
      Expr2026254
    Drives_construct: WBCnstr00003261
    Microarray_results: SMD_Y57A10A.U
      187073_at
      A_12_P104535
      Aff_Y57A10A.W
      GPL13394_WBGene00013263
      GPL13914_Y57A10A.23
      GPL14144_Y57A10A.23_117-176_0.941_9_C
      GPL14144_Y57A10A.23_254-313_0.943_7_B
      GPL14144_Y57A10A.23_417-476_0.958_1_A
      GPL19516_CGZ0049493
      GPL21109_Y57A10A.23
      GPL3518_CE22626
      GPL8304_CE_WBGene00013263_A
      GPL8304_CE_WBGene00013263_B
      GPL8304_CE_WBGene00013263_C
      GPL8673_Y57A10A_23P00010
      GPL8673_Y57A10A_23P00413
      GPL8673_Y57A10A_23P00488
      GPL9450_Y57A10A.23
      cea2.c.15582
    Expression_cluster: WBPaper00032528:L3_enriched
      WBPaper00035073:mitochondria_protein
      WBPaper00037950:hypodermis_CoreEnriched
      WBPaper00037950:hypodermis_embryo_enriched
      WBPaper00037950:hypodermis_embryo_SelectivelyEnriched
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:hypodermis_larva_enriched
      WBPaper00037950:hypodermis_larva_SelectivelyEnriched
      WBPaper00038289:oocyte_protein
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040134:nhr-49(RNAi)_regulated_protein
      WBPaper00040209:B.thuringiensis_downregulated_MY15
      WBPaper00040965:lipid-droplet_associated_protein
      WBPaper00042477:rsr-2(RNAi)_downregulated_RNAseq
      WBPaper00043945:MeHg_upregulated
      WBPaper00044128:daf-2(e1370)_upregulated
      WBPaper00044128:DietaryRestriction_downregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:oscillating_dev_expression
      WBPaper00044746:aging_downregulated_Day5
      WBPaper00044746:aging_downregulated_HeatShock
      WBPaper00044786:lem-2(tm1582)_upregulated
      WBPaper00045257:bar-1(ga80)_downregulated
      WBPaper00045390:ubc-9(RNAi)_upregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045774:clk-1_downregulated
      WBPaper00046012:tdp-1(ok803)_upregulated
      WBPaper00046121:ecdoderm_unique
      WBPaper00046337:monosomal_N2_vs_daf-2_downregulated
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_downregulated
      WBPaper00046337:polysomal_N2_vs_daf-2_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_downregulated_protein
      WBPaper00046499:AMPK_regulated
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049083:post-dauer-development_downregulated
      WBPaper00049098:heat-induced_hrde-1(tm1200)
      WBPaper00049217:DAF-16_downregulated
      WBPaper00049498:npr-1(ur89)_regulated_3
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
      WBPaper00049942:HeatShock_upregulated_hsf-1(+)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050193:met-2(n4256)set-25(n5021)_downregulated_L1
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050370:dpy-21(e428)_L3_downregulated
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051311:VGLN-1-interacting
      WBPaper00051352:Long-Term-Association-Memory_upregulated
      WBPaper00051388:Glucose-diet_upregulated
      WBPaper00051404:alg-1(gk214)_downregulated
      WBPaper00051404:alg-2(ok304)_downregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053023:nrx-1(tm1961);nlg-1(ok259)_upregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:stavudine_72h_regulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053321:PGCs_depleted_NuGen
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053402:cco-1(RNAi)_downregulated
      WBPaper00053599:female_vs_male_downregulated
      WBPaper00053599:oocyte_vs_mitosis_downregulated
      WBPaper00053615:SMO-1_target
      WBPaper00053657:N2_M.humicola-infection_24hr
      WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00053814:15C_downregulated_OP50
      WBPaper00053814:15C_downregulated_PY79
      WBPaper00054410:set-9(rw5)_downregulated
      WBPaper00054493:hpl-2(tm1489)_upregulated
      WBPaper00055013:hmg-3(bar24)_downregulated
      WBPaper00055013:spt-16(RNAi)_downregulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055354:Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055482:Tunicamycin_upregulated
      WBPaper00055626:pry-1(mu38)_upregulated
      WBPaper00055897:heat-shock_upregulated
      WBPaper00055941:atfs-1(et15)_upregulated
      WBPaper00055941:nuo-6(qm200)_downregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056039:efa-6(tm3124)_upregulated
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_upregulated
      WBPaper00056169:rrf-3(pk1426)_downregulated_L4
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056293:rpl-5(0)-rpl-33(0)_downregulated
      WBPaper00056330:glycine_downregulated
      WBPaper00056443:DietaryRestriction_upregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056826:SGP_biased
      WBPaper00056900:PID-3_interacting
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057041:unc-70(cas983)_upregulated
      WBPaper00057140:meg-3(tm4259)_meg-4(ax2026)_downregulated
      WBPaper00057154:HeatShock_upregulated_mRNA
      WBPaper00057288:Cold_downregulated_protein
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059224:tph-1(mg280)_upregulated
      WBPaper00059231:alh-6(lax105)_L4_upregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059567:olrn-1(ums9)_regulated
      WBPaper00059605:mut-16(pk710)_upregulated
      WBPaper00059605:MUT-16_interacting
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059735:glucose_downregulated_lpin-1(RNAi)
      WBPaper00059739:hira-1(gk835598)_downregulated_L4
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060224:atf-6(ok551)_upregulated
      WBPaper00060273:isp-1(qm150)_upregulated
      WBPaper00060273:vrk-1(RNAi)_downregulated
      WBPaper00060278:atp-2(RNAi)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060445:ikb-1(nr2027)_downregulated_L4
      WBPaper00060445:nfki-1(cer1)_downregulated_L4
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060908:TEBP-1_interacting
      WBPaper00061007:HB101_upregulated
      WBPaper00061007:HB115_upregulated
      WBPaper00061007:M.braciatum_upregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061007:X.citri_upregulated
      WBPaper00061203:let-418(n3536)_upregulated
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061274:hypergravity_10xg_upregulated
      WBPaper00061340:B_F_K_Kp_U_Y
      WBPaper00061340:G2_and_W_blasts
      WBPaper00061340:hyp4_hyp5_hyp6
      WBPaper00061340:hyp7_AB_lineage
      WBPaper00061340:hyp7_C_lineage
      WBPaper00061340:Hypodermis
      WBPaper00061340:P_cell
      WBPaper00061340:Seam_cell
      WBPaper00061340:T
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061527:mlt-9_22518-F33D4.6_14044
      WBPaper00061530:nhr-49(e2144)_downregulated
      WBPaper00061651:AMso_enriched
      WBPaper00061692:acivicin_upregulated
      WBPaper00062118:neural-HSF-1_downregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062184:PA14_downregulated
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062456:doxycycline_upregulated_CB4856_protein
      WBPaper00062497:xpf-1(tm2842)_upregulated
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062534:fat-P-80_downregulated
      WBPaper00062534:fat-P-80_downregulated_ech-6(RNAi)
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00062715:blmp-1(s71)_upregulated
      WBPaper00064071:NHR-49_interacting
      WBPaper00064080:miR-58_miRNA_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064229:B.thuringiensis-Cry5Ba_upregulated
      WBPaper00064306:Agaro-oligosaccharides_upregulated
      WBPaper00064403:Heat-killed-E.Coli_upregulated
      WBPaper00064502:spe-44(fx110)_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064728:cpl-1(W32AY35A)_upregulated
      WBPaper00064952:Day1_vs_L4_downregulated_20C
      WBPaper00064952:Day1_vs_L4_downregulated_25C
      WBPaper00064952:Day5_vs_Day1_downregulated_20C
      WBPaper00064952:Day5_vs_L4_downregulated_20C
      WBPaper00064952:Day5_vs_L4_downregulated_25C
      WBPaper00064952:Day10_vs_Day1_downregulated_20C
      WBPaper00064952:Day10_vs_L4_downregulated_20C
      WBPaper00064952:Day10_vs_L4_downregulated_25C
      WBPaper00065074:glna(-)_downregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065158:AFD_depleted
      WBPaper00065258:anchor-cell_enriched
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065581:hpk-1(pk1393)_upregulated
      WBPaper00065746:eat-2(ad1113)_downregulated
      WBPaper00065841:82_0
      WBPaper00065841:82_1
      WBPaper00065841:91_0
      WBPaper00065945:epidermis-rpoa-2(-)_downregulated_protein
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065984:pals-17(syb3980)_downregulated
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      cgc4386_cluster_4_6
      cgc4489_group_23
      WBPaper00025032:cluster_24
      WBPaper00025032:PAL-1_target_genes
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00028789:PA14_vs_gacA_downregulated_4hr
      WBPaper00028789:PA14_vs_gacA_downregulated_8hr
      WBPaper00028789:PA14_vs_OP50_downregulated_4hr
      WBPaper00028789:PA14_vs_OP50_downregulated_8hr
      WBPaper00031003:0hr_muscle_depleted
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:hlh_1_enriched
      WBPaper00031003:total_muscle_depleted
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00032948:FedUp
      WBPaper00033101:spr-5_regulated
      WBPaper00034757:down_by_oxidative_stress
      WBPaper00035588:alg-1(-)_upregulated
      WBPaper00035873:dpy-9_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00035873:osm-8_regulated
      WBPaper00036123:Atrazine_regulated
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_C
      WBPaper00036375:depleted_in_PVD_OLL
      WBPaper00036464:S.aureus-RN6390_regulated
      WBPaper00038172:tax-6null_down_regulated
      WBPaper00038304:octr-1_regulated
      WBPaper00040116:pRJ-FR.5_down_regulated
      WBPaper00040184:hcf-1down_sir-2.1down_daf-2nc
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.5
      WBPaper00040823:alg-1(gk214)_upregulated
      WBPaper00040963:Q100_down
      WBPaper00040963:Q200_down
      WBPaper00041002:HF_3d_2.0mM_Up
      WBPaper00041002:HF_11d_0.2mM_Up
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041207:CE_dauer_down
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042128:gei-8(ok1671)_downregulated
      WBPaper00042258:DA1877_downregulated_YoungAdult
      WBPaper00045673:colistin_upregulated
      WBPaper00046083:ogt-1(ok1474)_OP50_downregulated
      WBPaper00046083:pmk-1(km25)_OP50_downregulated
      WBPaper00046548:dafachronic-acid_upregulated
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00048624:hlh-25(ok1710)_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00050520:lagr-1(gk327);hyl-1(ok976)_upregulated
      WBPaper00055435:MUA-AuNP-0.5_upregulated
      WBPaper00055899:nitroguanidine_regulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
      [cgc5767]:cluster_5
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(101_min)
      [cgc5767]:expression_class_E_pi(122_min)
      [cgc5767]:expression_class_SE
      [cgc5767]:expression_class_SE_pi(101_min)
      [cgc5767]:expression_class_SE_pi(122_min)
      [cgc6390]:Cluster_B
    Interaction: WBInteraction000031662
      WBInteraction000551993
      WBInteraction000562077
      WBInteraction000568061
      WBInteraction000568465
      WBInteraction000570837
      WBInteraction000571062
      WBInteraction000582211
      WBInteraction000585637
  Map_info: Map: II Position: 7.28631
    Positive: Positive_clone: Y57A10A Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
    WBPaper00061547
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene