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WormBase Tree Display for Gene: WBGene00021552

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Name Class

WBGene00021552SMapS_parentSequenceY44E3B
IdentityVersion2
NameCGC_namezip-4Person_evidenceWBPerson1997
WBPerson460
Sequence_nameY44E3B.1
Molecular_name (11)
Other_nameCELE_Y44E3B.1Accession_evidenceNDBBX284601
Public_namezip-4
DB_infoDatabaseAceViewgene1D834
WormQTLgeneWBGene00021552
WormFluxgeneWBGene00021552
NDBlocus_tagCELE_Y44E3B.1
PanthergeneCAEEL|WormBase=WBGene00021552|UniProtKB=H2L0N3
familyPTHR23334
NCBIgene171900
RefSeqproteinNM_001047238.7
NM_058732.5
NM_001381600.2
SwissProtUniProtAccH2L0N3
TREEFAMTREEFAM_IDTF317778
UniProt_GCRPUniProtAccH2L0N3
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:04WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
218 Jul 2005 13:34:00WBPerson2970Name_changeCGC_namezip-4
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classzip
Allele (54)
RNASeq_FPKM (74)
GO_annotation00023210
00023211
00023212
00023213
00023214
00023215
00023216
00023217
00125880
00125881
Ortholog (18)
ParalogWBGene00016754Caenorhabditis elegansFrom_analysisPanther
WBGene00016997Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00017755Caenorhabditis elegansFrom_analysisPanther
WBGene00019327Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionzip-4 encodes, by alternative splicing, two isoforms of a putative C/EBP protein, divergently orthologous to human human CEBPA (OMIM:116897, mutated in acute myeloid leukemia), CEBPB (OMIM:189965), CEBPD (OMIM:116898), CEBPE (OMIM:600749, mutated in specific granule deficiency), and CEBPG (OMIM:138972); ZIP-4 is paralogous to CEBP-1; ZIP-4 is weakly expressed in what may be a ubiquitous, constitutive pattern, with higher expression in pharynx, vulva and spermatheca, and somewhat higher expression in the rest of the somatic gonad; ZIP-4 has no obvious function in mass RNAi assays.Paper_evidenceWBPaper00027309
WBPaper00029055
Curator_confirmedWBPerson1843
Date_last_updated27 Mar 2008 00:00:00
Automated_descriptionPredicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in defense response to Gram-negative bacterium. Predicted to be located in nucleus. Expressed in gonad; pharynx; spermatheca; and vulva.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSY44E3B.1a
Y44E3B.1b
Y44E3B.1c
Corresponding_transcriptY44E3B.1a.1
Y44E3B.1a.2
Y44E3B.1b.1
Y44E3B.1b.2
Y44E3B.1c.1
Other_sequence (16)
Associated_featureWBsf649017
WBsf649018
WBsf649019
WBsf976653
WBsf976654
WBsf978452
WBsf983097
WBsf219116
WBsf219117
Transcription_factorWBTranscriptionFactor000863
Experimental_infoRNAi_resultWBRNAi00056561Inferred_automaticallyRNAi_primary
WBRNAi00004619Inferred_automaticallyRNAi_primary
Expr_patternExpr7715
Expr1024700
Expr1039431
Expr1160034
Expr2018158
Expr2036295
Drives_constructWBCnstr00012860
WBCnstr00024505
Construct_productWBCnstr00021813
WBCnstr00024505
Microarray_results (38)
Expression_clusterWBPaper00031040:TGF-beta_adult_downregulated
WBPaper00036375:enriched_in_PVD_OLL
WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:all-neurons_L2-larva_expressed
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:BAG-neuron_blastula-embryo_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00038168:lin-15B(n744)_upregulated
WBPaper00038438:S.marcescens_24hr_downregulated_TilingArray
WBPaper00044656:tatn-1(qd182)_downregulated
WBPaper00044736:flat_dev_expression
WBPaper00044786:emr-1(gk119)_downregulated
WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
WBPaper00045521:Gender_Neutral
WBPaper00045571:germline-ablation_downregulated
WBPaper00048988:neuron_expressed
WBPaper00049942:hsf-1(RNAi)_upregulated
WBPaper00050234:lin-28(RNAi)_upregulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:intestine_expressed
WBPaper00051039:germline_enriched
WBPaper00051404:alg-1(gk214)_upregulated
WBPaper00051558:fog-2(q71)_regulated
WBPaper00052884:emb-4(hc60)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053289:DREAM-target
WBPaper00053302:stavudine_24h_regulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
WBPaper00055648:germline_expressed
WBPaper00055971:nhl-2(ok818)_25C_upregulated
WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
WBPaper00056275:P.aeruginosa_downregulated
WBPaper00056275:P.aeruginosa_downregulated_atf-7(qd22qd130)_dependent
WBPaper00056275:P.aeruginosa_upregulated
WBPaper00056826:SGP_biased
WBPaper00057288:Cold_upregulated_transcript
WBPaper00057288:iff-1(RNAi)_upregulated_transcript
WBPaper00058725:sftb-1(cer6)_downregulated
WBPaper00058725:sftb-1(cer6)_upregulated
WBPaper00059356:BAZ-2_SET-6_interacting
WBPaper00059763:neuron_expressed
WBPaper00060683:hlh-11(ko1)_downregulated
WBPaper00060909:atfs-1(cmh15)_upregulated
WBPaper00061007:HB101_downregulated
WBPaper00061007:S.aquatilis_downregulated
WBPaper00061274:hypergravity_15xg_upregulated
WBPaper00061340:AMso_parent
WBPaper00061340:g2_parent
WBPaper00061340:I2_grandparent
WBPaper00061340:Neuroblast_BAG_SMDVx
WBPaper00061340:PVQ_parent
WBPaper00061527:cyn-10_19153-K12H4.2
WBPaper00061527:Y32B12B.2-F28C1.1
WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064716:paraquat_upregulated
WBPaper00065975:P-body_vs_WholeAnimal_enriched
WBPaper00065993:glp-1(e2141)_downregulated
WBPaper00066110:tetraploid_vs_diploid_downregulated
WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
cgc4489_group_2
WBPaper00005124:cholesterol_10-9M_regulated
WBPaper00006465:II_ethanol_late_induction
WBPaper00025032:cluster_20
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00030839:Embryo_Pan_Neuronal
WBPaper00031532:Larva_Pan_Neuronal_Enriched
WBPaper00035084:embryo_enriched_AIN-2_IP
WBPaper00035873:dpy-9_regulated
WBPaper00035873:dpy-10_regulated
WBPaper00035905:FBF-1_Associated
WBPaper00036123:Cadmium_regulated
WBPaper00037147:heatshock_upregulated
WBPaper00037611:RNP-8-associated
WBPaper00037695:WC_5-day
WBPaper00037901:GLD-1_mRNA_targets
WBPaper00038231:Cry5B_1.5-fold_upregulated
WBPaper00038427:lin-54_embryo_changed
WBPaper00040858:eQTL_age_regulated_developing
WBPaper00040858:eQTL_regulated_juvenile
WBPaper00040963:TA300_down
WBPaper00041002:HF_3d_0.2mM_Down
WBPaper00041002:HF_3d_2.0mM_Down
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_S.marcescens_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_3h
WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
WBPaper00041939:control_vs_UVC-exposed_3h
WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
WBPaper00042258:DA1877_downregulated_GravidAdult
WBPaper00042331:a-SWCNTs_downregulated
WBPaper00045263:nuo-6(qm200)_downregulated
WBPaper00047070:DAF-16-dependent_UV_response
WBPaper00047070:xpa-1_UV_upregulated
WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
WBPaper00055899:nitroguanidine_regulated
[cgc5767]:expression_class_M
[cgc5767]:expression_class_MD
[cgc5767]:expression_class_MD_pd(23_min)
[cgc5767]:expression_class_SM
[cgc5767]:expression_class_SMD
[cgc6390]:Cluster_E
[cgc6390]:oogenesis-enriched
InteractionWBInteraction000277727
WBInteraction000283869
WBInteraction000314550
WBInteraction000343998
WBInteraction000357524
WBInteraction000395026
WBInteraction000449491
WBInteraction000450460
WBInteraction000505231
WBInteraction000523841
WBInteraction000523842
WBInteraction000530032
WBInteraction000531726
WBInteraction000531904
WBInteraction000533228
WBInteraction000533374
WBInteraction000533420
WBInteraction000534440
Map_infoMapIPosition-4.16186Error0.030517
PositivePositive_cloneY44E3BInferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_dataMulti_point5317
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00051448
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene