WormBase Tree Display for Gene: WBGene00001663

WBGene00001663 SMap: S_parent: Sequence: T19C4
  Identity: Version: 1
    Name: CGC_name: gpa-1 Person_evidence: WBPerson625
      Sequence_name: T19C4.6
      Molecular_name: T19C4.6a
        T19C4.6a.1
        CE06470
        T19C4.6b
        CE42473
        T19C4.6b.1
      Other_name: CELE_T19C4.6 Accession_evidence: NDB BX284605
      Public_name: gpa-1
    DB_info: Database: AceView gene 5L656
        WormQTL gene WBGene00001663
        WormFlux gene WBGene00001663
        NDB locus_tag CELE_T19C4.6
        Panther gene CAEEL|WormBase=WBGene00001663|UniProtKB=P28051
          family PTHR10218
        NCBI gene 179546
        RefSeq protein NM_001129546.4
            NM_073439.3
        SwissProt UniProtAcc P28051
        TrEMBL UniProtAcc B2D6M7
        UniProt_GCRP UniProtAcc P28051
    Species: Caenorhabditis elegans
    History: Version_change: 1 07 Apr 2004 11:29:25 WBPerson1971 Event: Imported: Initial conversion from geneace
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gpa
    Allele (53)
    Legacy_information: [C.elegansII] pk1 : Tc1 insertion. Also excision derivative, no detectable phenotype. Cloned: 48% identity to GPA-3; gpa-1:lacZ expressed in some amphid and phasmid neurons, spicular neurons, some anterior pharyngeal cells. [Lochrie et al. 1991; PS; NL]
    Strain: WBStrain00028898
    RNASeq_FPKM (74)
    GO_annotation (14)
    Ortholog (46)
    Paralog (21)
    Structured_description: Concise_description: gpa-1 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases that is involved in chemotaxis to water-soluble odorants; it is expressed in sensory neurons and in the spicule and phasmid neurons of the male tail. Curator_confirmed: WBPerson48
            WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Expressed in several structures, including SPD; chemosensory neurons; head mesodermal cell; pharyngeal neurons; and postcloacal sensillum. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: T19C4.6a
      T19C4.6b
    Corresponding_transcript: T19C4.6a.1
      T19C4.6b.1
    Other_sequence: Oden_isotig14911
      Dviv_isotig33463
      JI238621.1
      Oden_isotig14910
      JO473508.1
    Associated_feature: WBsf669360
      WBsf1001286
      WBsf1001287
      WBsf1020415
      WBsf1020416
  Experimental_info: RNAi_result: WBRNAi00053517 Inferred_automatically: RNAi_primary
      WBRNAi00027599 Inferred_automatically: RNAi_primary
      WBRNAi00018833 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr522
      Expr1303
      Expr15370
      Expr1025482
      Expr1157085
      Expr2012190
      Expr2030426
    Drives_construct: WBCnstr00001684
      WBCnstr00004644
      WBCnstr00004645
      WBCnstr00004648
      WBCnstr00036792
    Construct_product: WBCnstr00001681
      WBCnstr00001684
      WBCnstr00010199
      WBCnstr00036792
    Microarray_results (19)
    Expression_cluster: WBPaper00031040:Cluster_4
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037682:sma-2_downregulated
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_larva_enriched
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045521:Gender_Neutral
      WBPaper00045774:clk-1_upregulated
      WBPaper00045861:set-2(ok952)_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
      WBPaper00046805:csr-1(RNAi)_upregulated_Set1
      WBPaper00046805:csr-1(RNAi)_upregulated_Set2
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049626:UNC-75_target
      WBPaper00050412:cco-1(RNAi)_upregulated_lin-65(n3441)
      WBPaper00050412:cco-1(RNAi)_upregulated_met-2(ok2307)
      WBPaper00050412:cco-1(RNAi)_upregulated_N2
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050712:RC301_vs_DA650_4h-PA_upregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050743:elli-1(sam-3)_downregulated
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00051039:germline_enriched
      WBPaper00053295:lin-22(ot267)_upregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053302:alovudine_72h_regulated
      WBPaper00053318:Aging_downregulated_mRNA_N2
      WBPaper00053318:mir-71(n4115)_downregulated_mRNA
      WBPaper00053606:N2_vs_elt-2(ca15)_downregulated
      WBPaper00053810:daf-2(e1370)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053888:drh-3(rrr2)_upregulated
      WBPaper00054410:set-26(tm2467)_upregulated
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00055103:thoc-5(wy822)_upregulated
      WBPaper00055354:Allantoin_upregulated
      WBPaper00055354:Psora_upregulated
      WBPaper00055354:Rapamycin-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Psora_downregulated
      WBPaper00055827:daf-2(e1370)_upregulated
      WBPaper00055941:atfs-1(et15)_upregulated
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00057041:spc-1(cas971)_downregulated
      WBPaper00057068:ints-4(RNAi)_upregulated
      WBPaper00057068:ints-4(RNAi)_upregulated_Cadmium
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058942:henn-1(pk2295)_downregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059440:GLP-1_activated
      WBPaper00059471:EGL-43_interacting
      WBPaper00059605:mut-16(pk710)_downregulated
      WBPaper00059754:E.faecalis_OG1RF_upregulated
      WBPaper00060084:cco-1(RNAi)_upregulated_lin-40(yth27)
      WBPaper00060084:cco-1(RNAi)_upregulated_N2
      WBPaper00060459:bcat-1(RNAi)_upregulated
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00060909:atfs-1(et18)_upregulated
      WBPaper00061081:skpo-1(ok1640)_downregulated_OP50
      WBPaper00061340:ADL
      WBPaper00061340:ASJ
      WBPaper00061340:ASK
      WBPaper00061478:pie-1(ne4433)_upregulated
      WBPaper00061479:hda-1(ne4752)_upregulated
      WBPaper00061479:ubc-9(ne4833)_upregulated
      WBPaper00061527:acy-2-F35C5.11
      WBPaper00062103:neuron_enriched
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064130:Beta-Amyloid_24h_downregulated_mRNA
      WBPaper00064201:SNA-3_interacting
      WBPaper00064315:mes-3(bn199)_upregulated_EGCs
      WBPaper00064637:cox-5B(RNAi)_upregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:npr-8(ok1439)_upregulated_Day1_25C
      WBPaper00065096:npr-8(ok1439)_upregulated_Day10_20C
      WBPaper00065096:npr-8(ok1439)_upregulated_Day10_25C
      WBPaper00065841:24_0
      WBPaper00065841:24_1
      WBPaper00065841:92_0
      WBPaper00065841:96_0
      WBPaper00065841:135_0
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066085:sin-3(tm1276)_downregulated
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00006465:II_ethanol_late_induction
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00029437:rde-4_upregulated
      WBPaper00030839:Larval_Pan_Neuronal
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00035479:daf-16(RNAi)_upregulated
      WBPaper00035873:osmotically_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036123:Atrazine_regulated
      WBPaper00036286:Pattern_H
      WBPaper00038172:aak-2overexpression_down_regulated
      WBPaper00038427:lin-54_germline_changed
      WBPaper00039866:ClassComp_daf-19_downregulated
      WBPaper00039866:SAM_daf-19_downregulated
      WBPaper00040858:eQTL_age_regulated_aging
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040963:Q100_up
      WBPaper00041174:environmental
      WBPaper00041174:genotypic
      WBPaper00041174:genotypic_and_environmental
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_24h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00042548:miRISC_enriched
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00050407:hsp-6(RNAi)_upregulated
      WBPaper00050538:Fasting_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053550:daf-19(m86)_downregulated_3-fold-embryo
      WBPaper00055899:nitroguanidine_regulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
    Interaction: WBInteraction000126161
      WBInteraction000126163
      WBInteraction000126165
      WBInteraction000126166
      WBInteraction000126795
      WBInteraction000127136
      WBInteraction000127294
      WBInteraction000127295
      WBInteraction000133404
      WBInteraction000133440
      WBInteraction000134867
      WBInteraction000139145
      WBInteraction000147253
      WBInteraction000147254
      WBInteraction000165176
      WBInteraction000165177
      WBInteraction000180426
      WBInteraction000180428
      WBInteraction000180430
      WBInteraction000218495
      WBInteraction000218499
      WBInteraction000280664
      WBInteraction000301792
      WBInteraction000502743
      WBInteraction000555702
      WBInteraction000555703
      WBInteraction000561011
    WBProcess: WBbiopr:00000017
  Map_info: Map: V Position: 2.96783 Error: 0.001182
    Positive: Positive_clone: PS#25A12
        T19C4 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (49)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene