WBGene00000381 | SMap | S_parent | Sequence | F01F1 |
| Identity | Version | 1 |
| | Name | CGC_name | cct-6 | Person_evidence | WBPerson89 |
| | | Sequence_name | F01F1.8 |
| | | Molecular_name | F01F1.8a |
| | | | F01F1.8a.1 |
| | | | CE01234 |
| | | | F01F1.8b |
| | | | CE30647 |
| | | | F01F1.8a.2 |
| | | | F01F1.8b.1 |
| | | Other_name | CELE_F01F1.8 | Accession_evidence | NDB | BX284603 |
| | | Public_name | cct-6 |
| | DB_info | Database (11) |
| | Species | Caenorhabditis elegans |
| | History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace |
| | Status | Live |
| Gene_info | Biotype | SO:0001217 |
| | Gene_class | cct |
| | Allele (24) |
| | Legacy_information | [C.elegansII] NMK. Encodes one of 7-9 related subunits of eukaryotic cytosolic chaperonin CCT.Ortholog of mouse Cctz (67% aa sequence identity)[PC] |
| | | [C.elegansII] NMK. Encodes one of 7-9 related subunits of eukaryotic cytosolic chaperonin CCT. Ortholog of mouse Cctz (67% aa sequence identity)[PC] |
| | Strain | WBStrain00037224 |
| | RNASeq_FPKM (74) |
| | GO_annotation (12) |
| | Contained_in_operon | CEOP3336 |
| | Ortholog (41) |
| | Paralog | WBGene00000377 | Caenorhabditis elegans | From_analysis | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00000378 | Caenorhabditis elegans | From_analysis | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00000379 | Caenorhabditis elegans | From_analysis | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00000380 | Caenorhabditis elegans | From_analysis | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00020391 | Caenorhabditis elegans | From_analysis | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00021934 | Caenorhabditis elegans | From_analysis | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00018782 | Caenorhabditis elegans | From_analysis | Panther |
| | | | | | WormBase-Compara |
| | | WBGene00002025 | Caenorhabditis elegans | From_analysis | WormBase-Compara |
| | | WBGene00004089 | Caenorhabditis elegans | From_analysis | WormBase-Compara |
| | Structured_description | Concise_description | cct-6 encodes, by alternative splicing, two isoforms of a putative zeta subunit of the eukaryotic cytosolic ('T complex') chaperonin, orthologous to human CCT6A (OMIM:104613); CCT-6 represses SKN-1-dependent transcription of gst-4; CCT-6 is expressed in a few cells of pre-comma stage embryos; in mass RNAi assays, CCT-6 is required for normally short life span, and for normal transgene subcellular localization, embryonic and larval viability, fertility, vulval development, locomotion, and osmoregulation. | Paper_evidence (14) |
| | | | | Curator_confirmed | WBPerson567 |
| | | | | | WBPerson480 |
| | | | | Date_last_updated | 14 Jan 2008 00:00:00 |
| | | Automated_description | Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm. Predicted to be part of chaperonin-containing T-complex. Is an ortholog of human CCT6B (chaperonin containing TCP1 subunit 6B). | Paper_evidence | WBPaper00065943 |
| | | | | Curator_confirmed | WBPerson324 |
| | | | | | WBPerson37462 |
| | | | | Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase |
| | | | | Date_last_updated | 29 Nov 2023 00:00:00 |
| Molecular_info | Corresponding_CDS | F01F1.8a |
| | | F01F1.8b |
| | Corresponding_transcript | F01F1.8a.1 |
| | | F01F1.8a.2 |
| | | F01F1.8b.1 |
| | Other_sequence (166) |
| | Associated_feature | WBsf655405 |
| | | WBsf992556 |
| | | WBsf226726 |
| | | WBsf226727 |
| | | WBsf226728 |
| | | WBsf226729 |
| Experimental_info | RNAi_result (17) |
| | Expr_pattern | Expr2045 |
| | | Expr1011531 |
| | | Expr1030207 |
| | | Expr1147738 |
| | | Expr2009774 |
| | | Expr2028014 |
| | Drives_construct | WBCnstr00037582 |
| | Construct_product | WBCnstr00037582 |
| | Microarray_results (27) |
| | Expression_cluster | WBPaper00026640:Development_Group_I |
| | | WBPaper00031040:TGF-beta_adult_downregulated |
| | | WBPaper00032425:up_in_rde-4 |
| | | WBPaper00032425:up_in_zfp-1 |
| | | WBPaper00032528:L3_enriched |
| | | WBPaper00035963:S.aureus_24h_downregulated |
| | | WBPaper00036291:ung-1_regulated |
| | | WBPaper00036662:oxidative_modification |
| | | WBPaper00037047:aging_accelerated_insoluble_protein |
| | | WBPaper00037047:insoluble_protein |
| | | WBPaper00037950:A-class-motor-neurons_L1-larva_expressed |
| | | WBPaper00037950:A-class-motor-neurons_L2-larva_expressed |
| | | WBPaper00037950:all-neurons_L2-larva_expressed |
| | | WBPaper00037950:AVA-neuron_L1-larva_expressed |
| | | WBPaper00037950:BAG-neuron_blastula-embryo_expressed |
| | | WBPaper00037950:bodywall-muscle_L1-larva_expressed |
| | | WBPaper00037950:bodywall-muscle_L2-larva_expressed |
| | | WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed |
| | | WBPaper00037950:coelomocytes_L2-larva_expressed |
| | | WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed |
| | | WBPaper00037950:excretory-cell_L2-larva_expressed |
| | | WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed |
| | | WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed |
| | | WBPaper00037950:intestine_L2-larva_expressed |
| | | WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed |
| | | WBPaper00038118:aak-2(gt33)_upregulated |
| | | WBPaper00038289:oocyte_protein |
| | | WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq |
| | | WBPaper00040446:insoluble_protein |
| | | WBPaper00041072:UTX-1_interacting_protein |
| | | WBPaper00043951:insoluble_protein_day16_N2 |
| | | WBPaper00044426:rotenone_24h_downregulated |
| | | WBPaper00044656:tatn-1(qd182)_downregulated |
| | | WBPaper00044736:flat_dev_expression |
| | | WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated |
| | | WBPaper00045316:prg-1_upregulated_L1 |
| | | WBPaper00045420:fertilization_downregulated_transcript |
| | | WBPaper00045460:pept-1(lg601)_downregulated |
| | | WBPaper00045521:Gender_Neutral |
| | | WBPaper00045774:clk-1_downregulated |
| | | WBPaper00046303:P.aeruginosa_upregulated_protein |
| | | WBPaper00046421:cdc-48.2(tm659)_upregulated |
| | | WBPaper00048910:mRNA-interacting_protein |
| | | WBPaper00048988:neuron_expressed |
| | | WBPaper00050199:hsf-1(ok600)_downregulated |
| | | WBPaper00050686:glp-1(e2141)_downregulated |
| | | WBPaper00050698:DEP-1_interacting |
| | | WBPaper00050726:starvation_regulated_LowSalt |
| | | WBPaper00050990:arcade_intestinal-valve_expressed |
| | | WBPaper00050990:GABAergic-neuron_expressed |
| | | WBPaper00050990:hypodermis_expressed |
| | | WBPaper00050990:intestine_expressed |
| | | WBPaper00050990:NMDA-neuron_expressed |
| | | WBPaper00050990:seam_expressed |
| | | WBPaper00051039:germline_enriched |
| | | WBPaper00051245:body-wall-muscle_cytoplasm_expressed |
| | | WBPaper00051245:body-wall-muscle_nucleus_expressed |
| | | WBPaper00051245:epidermis_cytoplasm_expressed |
| | | WBPaper00051245:epidermis_nucleus_expressed |
| | | WBPaper00051245:intestine_cytoplasm_expressed |
| | | WBPaper00051245:intestine_nucleus_expressed |
| | | WBPaper00051245:pharyngeal-muscle_cytoplasm_expressed |
| | | WBPaper00052884:emb-4(hc60)_downregulated |
| | | WBPaper00052987:UV_downregulated_xpc-1;csb-1 |
| | | WBPaper00053184:sma-2(rax5)_downregulated |
| | | WBPaper00053184:sma-4(rax3)_downregulated |
| | | WBPaper00053254:hsp-90(RNAi)_upregulated_protein |
| | | WBPaper00053289:DREAM-target |
| | | WBPaper00053302:alovudine_24h_regulated |
| | | WBPaper00053302:stavudine_24h_regulated |
| | | WBPaper00053302:zidovudine_24h_regulated |
| | | WBPaper00053302:zidovudine_72h_regulated |
| | | WBPaper00053615:SMO-1_target |
| | | WBPaper00053810:daf-2(e1370)_downregulated |
| | | WBPaper00053810:isp-1(qm150)_downregulated |
| | | WBPaper00053814:25C_downregulated_OP50 |
| | | WBPaper00053814:25C_downregulated_PY79 |
| | | WBPaper00055013:HMG-3_interacting_protein |
| | | WBPaper00055049:S.gordonii_upregulated |
| | | WBPaper00055334:DLC-1_interacting |
| | | WBPaper00055648:germline_expressed |
| | | WBPaper00056034:pals-22(jy3)_downregulated |
| | | WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047) |
| | | WBPaper00056443:sek-1(km4)_downregulated |
| | | WBPaper00056471:S.aureus-4h_downregulated_N2 |
| | | WBPaper00056809:smn-1(ok355)_downregulated |
| | | WBPaper00056826:SGP_biased |
| | | WBPaper00057041:spc-1(cas971)_upregulated |
| | | WBPaper00057041:unc-70(cas983)_upregulated |
| | | WBPaper00057288:Cold_downregulated_protein |
| | | WBPaper00057288:Cold_downregulated_transcript |
| | | WBPaper00057288:iff-1(RNAi)_downregulated_transcript |
| | | WBPaper00057288:iff-1(RNAi)_upregulated_protein |
| | | WBPaper00058691:cfp-1(tm6369)_downregulated |
| | | WBPaper00058691:CFP-1_interacting_protein |
| | | WBPaper00058691:set-2(bn129)_downregulated |
| | | WBPaper00059174:MEG-3_interacting |
| | | WBPaper00059254:CSR-1_interacting |
| | | WBPaper00059254:PRG-1_interacting |
| | | WBPaper00059356:BAZ-2_SET-6_interacting |
| | | WBPaper00059471:EGL-43_interacting |
| | | WBPaper00059605:MUT-16_interacting |
| | | WBPaper00059763:neuron_expressed |
| | | WBPaper00061340:ALM_BDU |
| | | WBPaper00061340:ALM_PLM |
| | | WBPaper00061340:Neuroblast_ALM_BDU |
| | | WBPaper00061340:PLM |
| | | WBPaper00061341:28C_24h_downregulated |
| | | WBPaper00061377:MYRF-1_interacting |
| | | WBPaper00061478:SUMO-conjugated_protein |
| | | WBPaper00061479:HDA-1_interacting_protein |
| | | WBPaper00061527:tars-1-AFFX-r2-3026-5_at |
| | | WBPaper00061651:ALM_enriched |
| | | WBPaper00061651:PDE_enriched |
| | | WBPaper00061651:PLM_enriched |
| | | WBPaper00061651:PVM_enriched |
| | | WBPaper00061902:camt-1(ok515)_regulated_RMG |
| | | WBPaper00062143:PQN-59_interacting |
| | | WBPaper00062159:hda-2(ok1479)_upregulated |
| | | WBPaper00062325:etr-1(lq61)_downregulated |
| | | WBPaper00062554:MAGU-2_interacting |
| | | WBPaper00062669:extracellular-vesicle_protein |
| | | WBPaper00064064:DAF-15_interacting |
| | | WBPaper00064071:NHR-49_interacting |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20) |
| | | WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141) |
| | | WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141) |
| | | WBPaper00064201:SNA-3_interacting |
| | | WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated |
| | | WBPaper00064315:mes-3(bn199)_downregulated_PGCs |
| | | WBPaper00064494:postdauer_downregulated_AWA |
| | | WBPaper00064716:paraquat_upregulated |
| | | WBPaper00064933:E.coli-binding_secret_protein |
| | | WBPaper00065120:body-muscle-transcriptome |
| | | WBPaper00065158:AFD_depleted |
| | | WBPaper00065945:epidermis-rpoa-2(-)_downregulated_protein |
| | | WBPaper00065975:P-body_vs_oocyte_depleted |
| | | WBPaper00065993:glp-1(e2141)_downregulated |
| | | WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14 |
| | | cgc4386_cluster_4_6 |
| | | cgc4489_group_3 |
| | | WBPaper00025032:cluster_150 |
| | | WBPaper00025141:N2_Expressed_Genes |
| | | WBPaper00025141:unc-4::GFP_Expressed_Genes |
| | | WBPaper00026929:sir-2.1_overexpression_regulated |
| | | WBPaper00026952:class_A |
| | | WBPaper00026980:intestine_enriched |
| | | WBPaper00031003:0hr_muscle_enriched |
| | | WBPaper00031003:total_muscle_enriched |
| | | WBPaper00032948:FedUp |
| | | WBPaper00036123:Fluoranthene_regulated |
| | | WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2 |
| | | WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.5 |
| | | WBPaper00041606:CE_B.thuringiensis-DB27_regulated |
| | | WBPaper00041606:CE_S.marcescens_regulated |
| | | WBPaper00041606:CE_X.nematophila_regulated |
| | | WBPaper00041939:control_vs_UVC-EtBr-exposed_51h |
| | | WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h |
| | | WBPaper00042128:gei-8(ok1671)_downregulated |
| | | WBPaper00045960:L1-L4-lethargus_downregulated |
| | | WBPaper00045960:L4-lethargus_downregulated |
| | | WBPaper00053236:Starvation_regulated_GR1307 |
| | | WBPaper00053236:Starvation_regulated_N2 |
| | | [cgc5767]:cluster_33 |
| | | [cgc5767]:expression_class_E |
| | | [cgc5767]:expression_class_ET |
| | | [cgc5767]:expression_class_E_pi(101_min) |
| | | [cgc5767]:expression_class_M |
| | | [cgc5767]:expression_class_MD |
| | | [cgc5767]:expression_class_MDE |
| | | [cgc5767]:expression_class_MDET |
| | | [cgc5767]:expression_class_MD_pd(41_min) |
| | | [cgc5767]:expression_class_MD_pd(53_min) |
| | | [cgc5767]:expression_class_ME |
| | | [cgc5767]:expression_class_MET |
| | | [cgc6390]:oogenesis-enriched |
| | Interaction (142) |
| Map_info | Map | III | Position | -1.43903 | Error | 5.4e-05 |
| | Positive | Positive_clone | F01F1 | Inferred_automatically | From sequence, transcript, pseudogene data |
| | Pseudo_map_position |
| Reference (21) |
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission |
| Method | Gene |