WormBase Tree Display for Gene: WBGene00007772
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WBGene00007772 | SMap | S_parent | Sequence | C27C12 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | egrh-1 | Person_evidence | WBPerson460 | |||
Sequence_name | C27C12.2 | ||||||
Molecular_name | C27C12.2 | ||||||
C27C12.2.1 | |||||||
CE40601 | |||||||
Other_name | CELE_C27C12.2 | Accession_evidence | NDB | BX284606 | |||
Public_name | egrh-1 | ||||||
DB_info | Database | AceView | gene | XP467 | |||
WormQTL | gene | WBGene00007772 | |||||
WormFlux | gene | WBGene00007772 | |||||
NDB | locus_tag | CELE_C27C12.2 | |||||
Panther | gene | CAEEL|WormBase=WBGene00007772|UniProtKB=Q18250 | |||||
family | PTHR23235 | ||||||
NCBI | gene | 181580 | |||||
RefSeq | protein | NM_078061.6 | |||||
SwissProt | UniProtAcc | Q18250 | |||||
TREEFAM | TREEFAM_ID | TF318980 | |||||
UniProt_GCRP | UniProtAcc | Q18250 | |||||
OMIM | gene | 129010 | |||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | egrh | ||||||
Allele (58) | |||||||
Strain | WBStrain00029951 | ||||||
WBStrain00051977 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (13) | |||||||
Ortholog (36) | |||||||
Paralog | WBGene00003480 | Caenorhabditis elegans | From_analysis | Panther | |||
WBGene00018990 | Caenorhabditis elegans | From_analysis | Panther | ||||
WBGene00009998 | Caenorhabditis elegans | From_analysis | Panther | ||||
WBGene00043705 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00009743 | Caenorhabditis elegans | From_analysis | Panther | ||||
WBGene00012735 | Caenorhabditis elegans | From_analysis | Panther | ||||
WBGene00044651 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
Structured_description | Concise_description | egrh-1 encodes a zinc finger protein that has similarity to the vertebrate EGR (early growth response factor) family of proteins, including the human EGR transcription factors; in C. elegans, EGRH-1 activity is required, non-autonomously in the gut and the somatic gonad, for regulation of oocyte meiotic maturation and ovulation; EGRH-1 is expressed in the somatic gonad, specifically in the gonadal sheath and distal tip cells, and in sperm, as well as in the gut, and other non-gonadal tissues. | Paper_evidence | WBPaper00037082 | |||
Curator_confirmed | WBPerson12884 | ||||||
WBPerson1843 | |||||||
WBPerson1823 | |||||||
WBPerson567 | |||||||
Date_last_updated | 12 Jan 2015 00:00:00 | ||||||
Automated_description | Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of oocyte maturation and negative regulation of ovulation. Located in nucleus and perinuclear region of cytoplasm. Expressed in body wall musculature; hermaphrodite somatic gonadal cell; nervous system; pharynx; and sperm. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); lung disease (multiple); and neuropathy (multiple). Is an ortholog of human EGR1 (early growth response 1) and EGR3 (early growth response 3). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model (19) | ||||||
Molecular_info | Corresponding_CDS | C27C12.2 | |||||
Corresponding_transcript | C27C12.2.1 | ||||||
Other_sequence (22) | |||||||
Associated_feature (14) | |||||||
Transcription_factor | WBTranscriptionFactor000963 | ||||||
Experimental_info | RNAi_result | WBRNAi00092959 | Inferred_automatically | RNAi_primary | |||
WBRNAi00029263 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00110186 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00076168 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00041323 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00110187 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00110188 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00011248 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00114391 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00070166 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr9107 | ||||||
Expr1017133 | |||||||
Expr1033368 | |||||||
Expr1145368 | |||||||
Expr2011234 | |||||||
Expr2029470 | |||||||
Drives_construct | WBCnstr00008304 | ||||||
WBCnstr00008305 | |||||||
Construct_product | WBCnstr00008304 | ||||||
Antibody | WBAntibody00002152 | ||||||
Microarray_results (20) | |||||||
Expression_cluster (136) | |||||||
Interaction (21) | |||||||
Anatomy_function | WBbtf0409 | ||||||
WBbtf0410 | |||||||
WBbtf0411 | |||||||
WBbtf1061 | |||||||
Map_info | Map | X | Position | 21.4389 | Error | 0.005794 | |
Positive | Positive_clone | C27C12 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00027882 | ||||||
WBPaper00032994 | |||||||
WBPaper00037082 | |||||||
WBPaper00038491 | |||||||
WBPaper00055090 | |||||||
WBPaper00061738 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |