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WormBase Tree Display for Gene: WBGene00019537

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Name Class

WBGene00019537SMapS_parentSequenceK08D12
IdentityVersion1
NameSequence_nameK08D12.3
Molecular_nameK08D12.3a
K08D12.3a.1
CE21045
K08D12.3b
CE31712
K08D12.3b.1
Other_nameCELE_K08D12.3Accession_evidenceNDBBX284604
Public_nameK08D12.3
DB_infoDatabaseAceViewgene4C475
WormQTLgeneWBGene00019537
WormFluxgeneWBGene00019537
NDBlocus_tagCELE_K08D12.3
PanthergeneCAEEL|WormBase=WBGene00019537|UniProtKB=Q966I7
familyPTHR23002
NCBIgene176979
RefSeqproteinNM_171273.7
NM_001380057.1
TREEFAMTREEFAM_IDTF316974
TrEMBLUniProtAccQ966I7
Q8MXU9
UniProt_GCRPUniProtAccQ966I7
OMIMgene116955
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:01WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
StatusLive
Gene_infoBiotypeSO:0001217
Allele (16)
StrainWBStrain00001457
RNASeq_FPKM (74)
GO_annotation00084727
00084728
00084729
00084730
00084731
00084732
00084733
00124374
00124375
Ortholog (37)
ParalogWBGene00017210Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionK08D12.3 is orthologous to human ZNF9 (CNBP; OMIM:116955, mutated in myotonic dystrophy type 2) and ZCCHC13; like ZNF9, K08D12.3 is most conspicuously expressed in muscle cells; K08D12.3 is required for normal locomotion in mass RNAi assays, as well as for fertility, embryonic and larval viability, and general health.Paper_evidenceWBPaper00005654
WBPaper00006395
WBPaper00006510
WBPaper00006525
WBPaper00024925
WBPaper00025054
WBPaper00030851
Curator_confirmedWBPerson1823
WBPerson567
Date_last_updated20 Jul 2007 00:00:00
Automated_descriptionPredicted to enable mRNA binding activity; single-stranded RNA binding activity; and translation regulator activity. Predicted to be involved in positive regulation of cytoplasmic translation. Predicted to be located in cytoplasm. Expressed in head muscle and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in myotonic dystrophy type 2. Is an ortholog of human ZCCHC13 (zinc finger CCHC-type containing 13).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0050759Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:13164)
Molecular_infoCorresponding_CDSK08D12.3a
K08D12.3b
Corresponding_transcriptK08D12.3a.1
K08D12.3b.1
Other_sequence (82)
Associated_featureWBsf047615
WBsf659926
WBsf977050
WBsf977051
WBsf977052
WBsf981676
WBsf227970
Experimental_infoRNAi_result (12)
Expr_patternChronogram881
Expr6360
Expr11587
Expr1022204
Expr1038442
Expr1153959
Expr2004904
Expr2023127
Drives_constructWBCnstr00002335
WBCnstr00019073
Microarray_results (32)
Expression_clusterWBPaper00028451:Low_abundance_spermatogenesis_enriched
WBPaper00029359_1217
WBPaper00029359_1280
WBPaper00029359_1353
WBPaper00029359_1444
WBPaper00029359_1504
WBPaper00029359_1538
WBPaper00029359_1548
WBPaper00029359_1604
WBPaper00030894:daf-2(e1370ts)_downregulated
WBPaper00032528:L3_enriched
WBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038118:aak-2(gt33)_upregulated
WBPaper00038118:stress_upregulated_N2
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044656:tatn-1(qd182)_downregulated
WBPaper00044736:flat_dev_expression
WBPaper00044746:aging_downregulated_HeatShock
WBPaper00044760:germline_specific
WBPaper00045521:Gender_Neutral
WBPaper00045571:germline-ablation_downregulated
WBPaper00045774:clk-1_downregulated
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00046509:htz-1(ok3099)_downregulated
WBPaper00046691:P1_enriched
WBPaper00048923:Aging_regulated
WBPaper00048988:neuron_expressed
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00049942:HeatShock_downregulated_hsf-1(RNAi)
WBPaper00049942:hsf-1(RNAi)_downregulated
WBPaper00050234:lin-28(RNAi)_upregulated
WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
WBPaper00050488:20C_vs_25C_regulated_N2_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050698:DEP-1_interacting
WBPaper00050726:OsmoticStress_regulated_Food
WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050859:downregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050990:arcade_intestinal-valve_expressed
WBPaper00050990:body-muscle_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:hypodermis_expressed
WBPaper00050990:intestine_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00050990:pharynx_expressed
WBPaper00050990:seam_expressed
WBPaper00051039:germline_enriched
WBPaper00051265:F4_morc-1(tm6048)_downregulated
WBPaper00051558:aging_regulated
WBPaper00052884:emb-4(hc60)_downregulated
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053184:sma-4(rax3)_downregulated
WBPaper00053289:DREAM-target
WBPaper00053302:stavudine_24h_regulated
WBPaper00053308:SMG-2_associated_NMD(-)_upregulated_ClassI
WBPaper00053388:dauer_regulated_Cluster6
WBPaper00053615:SMO-1_target
WBPaper00053713:Pheromone-induced_postdauer_vs_control_downregulated
WBPaper00053792:Ochrobactrum_downregulated
WBPaper00053810:isp-1(qm150)_downregulated
WBPaper00053810:nuo-6(qm200)_downregulated
WBPaper00053814:25C_downregulated_OP50
WBPaper00053814:25C_downregulated_PY79
WBPaper00055060:flr-1(RNAi)_downregulated
WBPaper00055354:Rifampicin_downregulated
WBPaper00055648:germline_expressed
WBPaper00055827:daf-2(e1370)_downregulated
WBPaper00055971:nhl-2(ok818)_20C_downregulated
WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_downregulated_N2
WBPaper00056284:ints-1(RNAi)_downregulated
WBPaper00056284:ints-5(RNAi)_downregulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056809:smn-1(ok355)_downregulated
WBPaper00056826:SGP_biased
WBPaper00056997:nmad-1(ok3133)_downregulated_germline_25C
WBPaper00057041:unc-70(cas983)_upregulated
WBPaper00057288:Cold_downregulated_protein
WBPaper00057288:Cold_downregulated_transcript
WBPaper00057288:iff-1(RNAi)_upregulated_protein
WBPaper00058691:CFP-1_interacting_protein
WBPaper00058691:sin-3(tm1276)_downregulated
WBPaper00059440:LAG-1_activated_4hr-auxin
WBPaper00059471:EGL-43_interacting
WBPaper00059763:neuron_expressed
WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
WBPaper00060084:cco-1(RNAi)_downregulated_N2
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060445:nfki-1(cer1)_upregulated_L1
WBPaper00060683:hlh-11(ko1)_downregulated
WBPaper00060908:TEBP-2_interacting
WBPaper00061045:Y56A3A.22(cck200)_downregulated
WBPaper00061341:28C_24h_downregulated
WBPaper00061341:28C_48h_downregulated
WBPaper00061377:MYRF-1_interacting
WBPaper00061439:unc-30(ok613)_upregulated
WBPaper00061527:cdc-42_17192-rab-5_18073
WBPaper00061651:Germline_enriched
WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
WBPaper00062143:PQN-59_interacting
WBPaper00062354:H.zoospora_6h_regulated
WBPaper00062498:PPM-1.D_interacting
WBPaper00062554:MAGU-2_interacting
WBPaper00062669:extracellular-vesicle_protein
WBPaper00064055:trl-1(cas1077)_downregulated_starved
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064122:vulva_transcriptome
WBPaper00064315:mes-4(bn73)_downregulated_EGCs
WBPaper00064315:mes-4(bn73)_downregulated_PGCs
WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
WBPaper00064716:paraquat_upregulated
WBPaper00065120:body-muscle-transcriptome
WBPaper00065149:lin-52(n771)_downregulated
WBPaper00065158:AFD_depleted
WBPaper00065373:sek-1(km4)_upregulated_cisplatin
WBPaper00065993:glp-1(e2141)_downregulated
WBPaper00066085:sin-3(syb2172)_downregulated
WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
cgc4489_group_1
cgc4489_group_3
WBPaper00025032:cluster_78
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00026980:intestine_enriched
WBPaper00031003:24hr_muscle_enriched
WBPaper00031003:total_muscle_enriched
WBPaper00032948:FedUp
WBPaper00034757:down_by_oxidative_stress
WBPaper00037695:WC_5-day
WBPaper00038231:Cry5B_1.5-fold_downregulated
WBPaper00038231:Cry5B_2-fold_downregulated
WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
WBPaper00040963:TA100_up
WBPaper00040963:TA300_up
WBPaper00041606:CE_S.marcescens_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00042128:gei-8(ok1671)_downregulated
WBPaper00042548:miRISC_enriched
WBPaper00045263:nuo-6(qm200)_downregulated
WBPaper00047070:N2_starvation_downregulated
WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
WBPaper00048989:N2_allantoin_upregulated
WBPaper00053236:Starvation_regulated_GR1307
WBPaper00053236:Starvation_regulated_N2
[cgc6390]:intrinsic
Interaction (123)
Map_infoPositivePositive_cloneK08D12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionIV-16.1637
ReferenceWBPaper00038491
WBPaper00044833
WBPaper00055090
MethodGene