psa-3 encodes a Meis-related protein; along with nob-1 and ceh-20, psa-3 is required for the proper asymmetric cell division of the T hypodermal cell; a PSA-3::GFP reporter fusino is expressed in the T hypodermal cell, head neurons, posterior gut cells, hypodermal cells (hyp7, hyp9, and hyp10), and the P blast cells; psa-3 expression is regulated by the POP-1 TCF transcription factor, as well as CEH-20/Pbx and the NOB-1 homeodomain protein; PSA-3 physically interacts with CEH-20 and regulates its nuclear localization.
Enables transcription coactivator binding activity. Involved in regulation of asymmetric cell division. Located in nucleus. Expressed in several structures, including TL.aa; TL.pa; TR.aa; TR.pa; and hypodermal cell.
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.