WormBase Tree Display for Gene: WBGene00020453

WBGene00020453 SMap: S_parent: Sequence: CHROMOSOME_III
  Identity: Version: 2
    Name: CGC_name: fbxa-55 Person_evidence: WBPerson655
      Sequence_name: T12B5.6
      Molecular_name: T12B5.6b
        T12B5.6a
        CE39403
        T12B5.6c
        CE51680
        T12B5.6b.1
        T12B5.6c.1
      Other_name: CELE_T12B5.6 Accession_evidence: NDB BX284603
      Public_name: fbxa-55
    DB_info: Database (10)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:03 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 12 Dec 2005 15:18:56 WBPerson2970 Name_change: CGC_name: fbxa-55
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: fbxa
    Allele: WBVar02122810
      WBVar01606478
      WBVar02124101
      WBVar02120976
      WBVar02120977
      WBVar02120978
      WBVar02122452
      WBVar01540528
      WBVar01540529
      WBVar01500082
      WBVar01540530
      WBVar02123377
      WBVar00559508
      WBVar00388939
      WBVar01627681
      WBVar01917851
      WBVar02101304
      WBVar02123578
      WBVar01499552
      WBVar02124686
      WBVar02121742
      WBVar01322754
      WBVar01322755
      WBVar02122116
      WBVar01322756
      WBVar01322759
      WBVar01322760
      WBVar01322762
      WBVar01322763
      WBVar02120832
      WBVar01322764
      WBVar01498832
      WBVar01322765
      WBVar01322770
      WBVar01322771
      WBVar02120474
      WBVar02124343
      WBVar02121583
      WBVar02120666
      WBVar02121404
      WBVar01506239
      WBVar01506240
      WBVar01506241
      WBVar01506242
      WBVar00032718
      WBVar01506243
      WBVar01506244
      WBVar00032723
      WBVar02124181
      WBVar02121974
      WBVar00032728
      WBVar00032733
      WBVar00032738
      WBVar01255486
      WBVar01255491
      WBVar00032743
      WBVar02100637
      WBVar00032748
      WBVar02102112
      WBVar02011467
      WBVar00032753
      WBVar01643311
      WBVar00032758
      WBVar01643312
      WBVar01643313
      WBVar00032763
      WBVar00032768
      WBVar00032773
      WBVar01700475
      WBVar00032778
      WBVar02122559
      WBVar02012669
      WBVar01700476
      WBVar01700477
      WBVar02124401
      WBVar02124953
      WBVar00032788
      WBVar01415193
      WBVar01415194
      WBVar02122933
      WBVar00032793
      WBVar02123672
      WBVar00032798
      WBVar00602751
      WBVar02075584
      WBVar02124779
      WBVar00142753
      WBVar01769473
      WBVar01769474
      WBVar01769475
      WBVar01769476
      WBVar01769477
      WBVar01667123
      WBVar00800368
      WBVar00007881
      WBVar00800369
      WBVar00800370
      WBVar00800371
      WBVar00800372
      WBVar01389863
      WBVar00800373
      WBVar00800374
      WBVar01389871
      WBVar01389873
      WBVar00800375
      WBVar01389877
      WBVar00800376
      WBVar00800377
      WBVar01389879
      WBVar00800378
      WBVar00800379
      WBVar00800380
      WBVar00800381
      WBVar00800382
      WBVar02121865
      WBVar01893052
      WBVar01893053
      WBVar01548338
      WBVar01577849
      WBVar01577850
      WBVar01577851
      WBVar01577852
      WBVar02089496
      WBVar02087841
      WBVar01577853
    RNASeq_FPKM (74)
    Ortholog (25)
    Paralog (222)
    Structured_description: Concise_description: This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction. Paper_evidence: WBPaper00012854
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enriched in AFD; ASER; and intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray and RNA-seq studies. Is affected by twelve chemicals including rotenone; metformin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; FTH domain; and F-box A protein FB224. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: T12B5.6b
      T12B5.6c
    Corresponding_CDS_history: T12B5.6:wp151
      T12B5.6a:wp253
    Corresponding_transcript: T12B5.6a
      T12B5.6b.1
      T12B5.6c.1
    Other_sequence: Oden_isotig22831
    Associated_feature: WBsf991189
      WBsf1014150
  Experimental_info: RNAi_result: WBRNAi00035506 Inferred_automatically: RNAi_primary
      WBRNAi00018634 Inferred_automatically: RNAi_primary
      WBRNAi00053190 Inferred_automatically: RNAi_primary
      WBRNAi00006619 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1156782
      Expr2011557
      Expr2029795
    Drives_construct: WBCnstr00025127
    Construct_product: WBCnstr00025127
    Microarray_results (20)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00032425:down_in_rde-4
      WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_downregulated_TilingArray
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044037:eat-2_upregulated
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045316:prg-1_upregulated_L4
      WBPaper00045618:fbf-1_upregulated
      WBPaper00048988:daf-2(e1370)_daf-16(mu86)_downregulated_neuron
      WBPaper00048988:daf-2(e1370)_downregulated_neuron
      WBPaper00048988:neuron_expressed
      WBPaper00049334:CE_intestine_enriched
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050344:ASER-neuron_enriched
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_adult_25C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:intestine_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051404:alg-5(ram2)_downregulated
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053606:elt-2(ca15)_vs_elt-2(ca15);elt-7(tm840)_doenregulated
      WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_downregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053909:N2_vs_CB4856_upregulated
      WBPaper00055060:flr-1(RNAi)_upregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055827:daf-2(e1370)_upregulated
      WBPaper00056034:pals-22(jy3)_upregulated
      WBPaper00056034:pals-25(jy9)_upregulated
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056161:male_enriched_siRNA
      WBPaper00056284:ints-1(RNAi)_upregulated
      WBPaper00056443:sek-1(km4)_upregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00057006:DietaryRestriction_upregulated
      WBPaper00058711:paraquat_downregulated
      WBPaper00058711:wdr-5(ok1417)_downregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00058948:PA14_downregulated
      WBPaper00058958:10mGy-irradiation-72h_downregulated
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated
      WBPaper00061439:unc-30(ok613)_downregulated_P.aeruginosa-infection
      WBPaper00061527:172183_at-176110_at
      WBPaper00061530:nhr-49(e2144)_upregulated
      WBPaper00061653:alh-4(hj221)_downregulated
      WBPaper00062184:PA14_upregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_downregulated
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064532:pals-22(jy3)_upregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064939:vit-5(RNAi)_upregulated
      WBPaper00065086:JU1400_N.ferruginous_regulated
      WBPaper00065841:48_0
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00066110:Cisplatin_upregulated_diploid
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      WBPaper00024671:AFD_AWB_vs_unsorted_downregulated
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00027111:eri-1(mg366)_upregulated
      WBPaper00027111:rde-3(r459)_downregulated
      WBPaper00029437:dcr-1_upregulated
      WBPaper00029437:rde-4_upregulated
      WBPaper00030985:Erwinia_carotovora_downregulated
      WBPaper00034661:AgNPs_downregulated
      WBPaper00034739:N2moreDR1350
      WBPaper00034739:RIL17moreRIL14
      WBPaper00034757:up_by_oxidative_stress
      WBPaper00035227:heat_shock_regulated
      WBPaper00035873:dpy-10_regulated
      WBPaper00036123:Atrazine_regulated
      WBPaper00037704:ABZ_up_regulated
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00040603:tdp-1(lf)_up_vs_N2_FC_1.2
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_aging
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00040963:TA100_up
      WBPaper00040963:TA200_up
      WBPaper00040963:TA300_up
      WBPaper00041002:HQ_3d_2.0mM_Up
      WBPaper00041370:spg-7(RNAi)_upregulated
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-exposed_51h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00050515:nipi-3(fr4)_upregulated
      WBPaper00053236:daf-16(mgDF50)_regulated_Starved
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc6390]:mixed_spermatogenesis-somatic
    Interaction (27)
  Map_info: Map: III Position: -25.0866 Error: 0.003123
    Positive: Positive_clone: T12B5 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00012854
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene