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WormBase Tree Display for Gene: WBGene00010362

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Name Class

WBGene00010362SMapS_parentSequenceH04D03
IdentityVersion3
NameCGC_nameenu-3.1Person_evidenceWBPerson3027
Sequence_nameH04D03.1
Molecular_nameH04D03.1
H04D03.1.1
CE16165
Other_nameenu-3Person_evidenceWBPerson3027
CELE_H04D03.1Accession_evidenceNDBBX284603
Public_nameenu-3.1
DB_infoDatabaseAceViewgene3L527
WormQTLgeneWBGene00010362
WormFluxgeneWBGene00010362
NDBlocus_tagCELE_H04D03.1
PanthergeneCAEEL|WormBase=WBGene00010362|UniProtKB=O45607
familyPTHR31026
NCBIgene176463
RefSeqproteinNM_066901.6
TREEFAMTREEFAM_IDTF316689
TrEMBLUniProtAccO45607
UniProt_GCRPUniProtAccO45607
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
208 Feb 2011 16:27:44WBPerson2970Name_changeCGC_nameenu-3
328 Apr 2014 11:13:08WBPerson2970Name_changeCGC_nameenu-3.1
Other_nameenu-3
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classenu
AlleleWBVar00531929
WBVar01500260
WBVar02034241
WBVar00407328
WBVar00407329
WBVar00407330
WBVar00407331
WBVar00407332
WBVar01918770
WBVar01499194
WBVar01645959
WBVar01499774
WBVar01499594
WBVar01499595
WBVar00269978
WBVar00856465
WBVar00856466
WBVar00856467
WBVar00856468
WBVar00856469
WBVar00856470
WBVar00856471
WBVar00856472
WBVar00856473
WBVar00856474
WBVar00252950
WBVar01332798
WBVar01332799
WBVar01952613
WBVar02036297
WBVar01802382
RNASeq_FPKM (74)
GO_annotation00034852
00034853
00034854
00034855
00034856
00034857
00034858
Ortholog (21)
ParalogWBGene00008003Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00012552Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00021015Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00021034Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WBGene00010477Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionenu-3 encodes a novel protein containing a single transmembrane domain and, at 144-165 amino acids, a coiled-coil region; enu-3 mutations enhance the axonal outgrowth defects of unc-5, although enu-3 mutations alone cause no motor axon outgrowth defects; ENU-3 functions in the same pathway as UNC-5 and UNC-6 for motor axon guidance to the dorsal cord but in a pathway parallel to UNC-5 and UNC-6 for axon outgrowth; enu-3 mutants are mildly uncoordinated and have a slight egg-laying defective phenotype; the rescue of axon outgrowth defects of a strain lacking both ENU-3 and UNC-5 depended on the presence of functional ENU-3 protein; ENU-3 is expressed in the PVT interneuron and is weakly expressed in many cell bodies along the ventral cord, including those of the DA and DB motor neurons.Paper_evidenceWBPaper00038105
Curator_confirmedWBPerson12884
Date_last_updated02 Jun 2011 00:00:00
Automated_descriptionInvolved in axon extension involved in axon guidance. Located in neuronal cell body. Expressed in head; nervous system; and seam cell.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSH04D03.1
Corresponding_transcriptH04D03.1.1
Associated_featureWBsf994020
WBsf1015786
WBsf225719
WBsf225720
Experimental_infoRNAi_result (27)
Expr_patternExpr9239
Expr14491
Expr1024584
Expr1034524
Expr1153023
Expr2011330
Expr2029566
Drives_construct (6)
Construct_productWBCnstr00008437
WBCnstr00008439
WBCnstr00008440
WBCnstr00013845
WBCnstr00031469
WBCnstr00040912
Microarray_results (18)
Expression_clusterWBPaper00032425:up_in_lin-35
WBPaper00033065:cyc-1(RNAi)_upregulated
WBPaper00036291:ung-1_regulated
WBPaper00037950:A-class-motor-neurons_L1-larva_expressed
WBPaper00037950:all-neurons_L2-larva_expressed
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:AVE-neuron_L1-larva_expressed
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:germline-precursors_blastula-embryo_expressed
WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00038168:lin-15B(n744)_upregulated
WBPaper00038168:lin-35_upregulated
WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
WBPaper00040420:FLP_enriched
WBPaper00040560:hpl-2_embryo_upregulated
WBPaper00040560:hpl-2_L3_upregulated
WBPaper00044736:flat_dev_expression
WBPaper00044760:germline_specific
WBPaper00045420:fertilization_downregulated_transcript
WBPaper00045521:Spermatogenic
WBPaper00045571:germline-ablation_downregulated
WBPaper00046509:lin-35(n745)_upregulated
WBPaper00048971:daf-16(mgDf50)_downregulated_L1
WBPaper00048988:neuron_expressed
WBPaper00049098:hrde-1(tm1200)-induced_15C
WBPaper00049098:hrde-1(tm1200)-repressed_15C
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00049942:hsf-1(RNAi)_upregulated
WBPaper00050193:lsm-1(tm3585)_upregulated_L3
WBPaper00050193:met-2(n4256)set-25(n5021)_upregulated_L1
WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
WBPaper00050488:20C_vs_25C_regulated_N2_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050522:mafr-1(tm6082)_downregulated
WBPaper00050743:elli-1(sam-3)_upregulated
WBPaper00050859:downregulated_pgl-1(ct131)_vs_control_day1-adult
WBPaper00050990:intestine_enriched
WBPaper00050990:intestine_expressed
WBPaper00051039:germline_enriched
WBPaper00052884:emb-4(hc60)_downregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053289:DREAM-target
WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
WBPaper00053388:dauer_regulated_Cluster6
WBPaper00053599:female_vs_male_downregulated
WBPaper00053599:oocyte_vs_mitosis_upregulated
WBPaper00053606:N2_vs_elt-2(ca15);elt-7(tm840)_upregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00053814:25C_upregulated_OP50
WBPaper00053814:25C_upregulated_PY79
WBPaper00053888:drh-3(rrr2)_upregulated
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055354:Psora-Allantoin_upregulated
WBPaper00055354:Rapamycin-Metformin_upregulated
WBPaper00055354:Rifampicin-Allantoin_upregulated
WBPaper00055482:pmt-2(RNAi)_upregulated
WBPaper00055565:AVK_enriched
WBPaper00055648:germline_expressed
WBPaper00055862:antimycin_damt-1(gk961032)_regulated
WBPaper00055941:nuo-6(qm200)_upregulated
WBPaper00055971:nhl-2(ok818)_25C_upregulated
WBPaper00056284:ints-11(RNAi)_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00057041:spc-1(cas971)_upregulated
WBPaper00057041:unc-70(cas983)_upregulated
WBPaper00057143:ztf-11(RNAi)_downregulated
WBPaper00058691:cfp-1(tm6369)_upregulated
WBPaper00058691:set-2(bn129)_downregulated
WBPaper00058958:100mGy-irradiation-72h_upregulated
WBPaper00059356:BAZ-2_SET-6_interacting
WBPaper00059440:LAG-1_activated_4hr-auxin
WBPaper00059471:EGL-43_interacting
WBPaper00059605:mut-16(pk710)_upregulated
WBPaper00059605:simr-1(cmp36)_upregulated
WBPaper00059739:hira-1(gk835598)_upregulated_adult
WBPaper00059739:hira-1(gk835598)_upregulated_L1
WBPaper00060014:set-2(zr2012)_upregulated
WBPaper00060278:atp-2(RNAi)_upregulated
WBPaper00060661:sensory-neuron_enriched
WBPaper00060886:met-2(n4256)_upregulated
WBPaper00060886:spr-5(by101);met-2(n4256)_upregulated
WBPaper00061203:let-418(n3536)_upregulated
WBPaper00061203:spr-1(ok2144)_upregulated
WBPaper00061340:Neuroblast_IL1_IL2
WBPaper00061340:Parents_of_PHsh_hyp8_hyp9
WBPaper00061340:PLM_ALN_grandparent
WBPaper00061341:28C_48h_upregulated
WBPaper00061479:prg-1(tm872)_upregulated
WBPaper00061527:C16A11.5-C16C8.13
WBPaper00061651:I4_enriched
WBPaper00061651:SIA_enriched
WBPaper00062056:dpl-1(n2994)_upregulated
WBPaper00062056:lin-15B(n744)_upregulated
WBPaper00062056:lin-35(n745)_upregulated
WBPaper00062056:lin-37(n758)_upregulated
WBPaper00062056:met-2(n4256)_upregulated
WBPaper00062325:etr-1(lq61)_upregulated
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00062590:Aging_upregulated_coelomocyte
WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064107:lin-35(n745)_upregulated
WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
WBPaper00065149:lin-52(n771)_upregulated
WBPaper00065158:25C_vs_15C_upregulated_WholeAnimal
WBPaper00065749:Heat-Shock_upregulated_endu-2(tm4977)
WBPaper00065749:Heat-Shock_upregulated_N2
WBPaper00065841:46_0
WBPaper00065841:66_0
WBPaper00065841:129_0
WBPaper00065841:139_0
WBPaper00065993:glp-1(e2141)_downregulated
WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
WBPaper00066204:CdCl2_upregulated_mRNA
WBPaper00025141:N2_Expressed_Genes
WBPaper00025141:unc-4::GFP_Expressed_Genes
WBPaper00035227:heat_shock_regulated
WBPaper00036123:Atrazine_regulated
WBPaper00036286:Pattern_B
WBPaper00038172:aak-2overexpression_up_regulated
WBPaper00039866:ClassComp_daf-19_upregulated
WBPaper00039866:SAM_daf-19_upregulated
WBPaper00040210:Diazinon_24C_regulated
WBPaper00040858:eQTL_age_regulated_aging
WBPaper00040858:eQTL_regulated_old
WBPaper00041606:CE_B.thuringiensis-DB27_regulated
WBPaper00041606:CE_S.marcescens_regulated
WBPaper00041606:CE_X.nematophila_regulated
WBPaper00041609:hpl-1_hpl-2_upregulated
WBPaper00045015:nhr-25(RNAi)_downregulated
WBPaper00045263:nuo-6(qm200)_upregulated
WBPaper00048637:lin-35(n745)_starvation_upregulated
WBPaper00053550:daf-19(m86)_upregulated_3-fold-embryo
[cgc5767]:expression_class_M
[cgc5767]:expression_class_SM
[cgc5976]:class_2
[cgc6390]:Cluster_F
[cgc6390]:intrinsic
Interaction (20)
Map_infoMapIIIPosition2.50169Error0.003023
PositivePositive_cloneH04D03Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038105
WBPaper00044299
WBPaper00047925
WBPaper00051476
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene