WormBase Tree Display for Interaction: WBInteraction000558283
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WBInteraction000558283 | Interaction_type | Regulatory | Change_of_localization | ||
---|---|---|---|---|---|
Interactor | Interactor_overlapping_gene | WBGene00006882 | Interactor_type | Trans_regulated | |
Transgene | WBTransgene00000736 | ||||
Construct | WBCnstr00000732 | ||||
WBGene00002915 | Interactor_type | Trans_regulator | |||
Interaction_summary | "In Myotactin (let-805) mutants, VAB-19::GFP was normally localized to muscle-adjacent regions of the epidermis but never became distributed into circumferential stripes. Within 15-20 minutes of muscle contraction starting (~430 minutes), VAB-19::GFP became dispersed into puncta within epidermal cells (Fig. 6B). Thus, VAB-19 requires Myotactin for its subcellular localization in epidermal cells. By contrast, in vab-10A(ju281ts) mutants, VAB-19::GFP remained confined to the regions of epidermal cells overlying muscle (Fig. 6D) but never became localized to attachment structures." | ||||
Detection_method | Construct | ||||
Reporter_gene | [VAB-19::GFP] | ||||
Transgene | |||||
Regulation_level | Post_translational | ||||
Regulation_result | Positive_regulate | Life_stage | WBls:0000003 | ||
Anatomy_term | WBbt:0005733 | ||||
Subcellular_localization | attachment structures | ||||
Paper | WBPaper00006290 | ||||
Remark | Fig. 6b |