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WormBase Tree Display for Interaction: WBInteraction000501741

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Name Class

WBInteraction000501741Interaction_typeRegulatoryChange_of_expression_level
InteractorInteractor_overlapping_geneWBGene00003221Interactor_typeTrans_regulated
Expr_patternExpr1736
AntibodyWBAntibody00000437
WBGene00003220Interactor_typeTrans_regulator
Variation_interactorWBVar00000462Interactor_typeTrans_regulator
Interaction_summaryIn the germlines of homozygous mes-2 hermaphrodites from heterozygous mothers, the level and distribution of MES-3 appeared normal. The embryos from these mes mutants, which develop into sterile adults, showed normal MES-3 patterns up to the 24-cell stage. However, at later stages, the level of MES-3 in nuclei gradually diminished in mes-2 mutant embryos. By the time of hatching, MES-3 was detected in the nuclei of the primordial germ cells, Z2 and Z3, in wild type, but was undetectable in those cells in mes-2 L1s.
Detection_methodAntibody
Regulation_levelPost_transcriptional
PaperWBPaper00005019