Ppa-unc-37/groucho encodes a transducin-like WD-repeat protein homologous to Drosophila GROUCHO; Ppa-groucho plays a prominent role in vulva induction, regulates the programmed cell death of P(3,4).p and limits the size of the vulva equivalence group; Ppa-groucho mutants are multivulva with P(3-7).p having vulval fates in a gonad-independent manner; Ppa-GROUCHO interacts and forms a dimer with Ppa-HAIRY, a basic Helix-Loop-Helix transcription factor that is missing in C. elegans; Ppa-GROUCHO and Ppa-HAIRY co-regulate P(3,4).p cell death.
Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans unc-37. In C. elegans, unc-37 is involved in chemical synaptic transmission; regulation of axonogenesis; and regulation of synapse structure or activity.