WormBase Tree Display for Gene: WBGene00194737

WBGene00194737 SMap: S_parent: Sequence: Y50D7A
  Identity: Version: 2
    Name: Sequence_name: Y50D7A.13
      Molecular_name: Y50D7A.13a
        Y50D7A.13a.1
        CE50830
        Y50D7A.13b
        CE50849
        Y50D7A.13b.1
      Other_name: CELE_Y50D7A.13 Accession_evidence: NDB BX284603
      Public_name: Y50D7A.13
    DB_info: Database: WormFlux gene WBGene00194737
        NDB locus_tag CELE_Y50D7A.13
        NCBI gene 13188188
        RefSeq protein NM_001312977.1
            NM_001312976.2
        TrEMBL UniProtAcc A0A0K3ARD1
            A0A0K3AUX6
        UniProt_GCRP UniProtAcc A0A0K3ARD1
    Species: Caenorhabditis elegans
    History: Version_change: 1 21 Aug 2009 11:07:44 WBPerson1867 Event: Created
        2 30 Apr 2015 13:34:49 WBPerson1983 Event: Acquires_merge: WBGene00194736
      Acquires_merge: WBGene00194736
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (133)
    RNASeq_FPKM (74)
    GO_annotation (14)
    Ortholog (29)
    Paralog: WBGene00006987 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00010423 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00010524 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00012185 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00012364 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00016283 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00019212 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00020646 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable metalloendopeptidase activity. Predicted to be involved in collagen catabolic process and extracellular matrix organization. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; artery disease (multiple); autoimmune disease (multiple); and carcinoma (multiple). Is an ortholog of human MMP2 (matrix metallopeptidase 2); MMP23B (matrix metallopeptidase 23B); and MMP9 (matrix metallopeptidase 9). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (122)
  Molecular_info: Corresponding_CDS: Y50D7A.13a
      Y50D7A.13b
    Corresponding_CDS_history: Y50D7A.13:wp248
    Corresponding_transcript: Y50D7A.13a.1
      Y50D7A.13b.1
    Associated_feature: WBsf650792
      WBsf991023
      WBsf991024
      WBsf991025
  Experimental_info: RNAi_result: WBRNAi00001652 Inferred_automatically: RNAi_primary
      WBRNAi00020835 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1040461
      Expr1040462
      Expr1160533
      Expr1160534
      Expr2007754
      Expr2025997
    Microarray_results: SMD_Y50D7_165.A
      Aff_Y50D7_165.A
      GPL19516_CGZ0047628
      GPL19516_CGZ0047629
      GPL21109_Y50D7A.12
      GPL21109_Y50D7A.13
    Expression_cluster: WBPaper00044656:tatn-1(qd182)_upregulated
      WBPaper00045316:prg-1_downregulated_L3
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00053388:dauer_regulated_Cluster5
      WBPaper00053402:cco-1(RNAi)_downregulated
      WBPaper00054493:hpl-2(tm1489)_upregulated
      WBPaper00055013:hmg-3(bar24)_downregulated
      WBPaper00055013:hmg-4(RNAi)_downregulated
      WBPaper00055013:spt-16(RNAi)_downregulated
      WBPaper00055334:DLC-1_interacting
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055386:eat-2(ad465)_downregulated
      WBPaper00055386:eat-2(ad465)_upregulated
      WBPaper00056169:rrf-3(pk1426)_downregulated_L4
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00057068:ints-4(RNAi)_downregulated_Cadmium
      WBPaper00058969:RIS_depleted
      WBPaper00059231:alh-6(lax105)_L4_upregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00060014:set-2(zr2012)_downregulated
      WBPaper00060445:nfki-1(cer1)_downregulated_L4
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060886:spr-5(by101);met-2(n4256)_upregulated
      WBPaper00061340:Tail_hypodermis
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061424:Diet_MYb120_upregulated
      WBPaper00061439:unc-30(ok613)_upregulated_P.aeruginosa-infection
      WBPaper00061613:human-alpha-Synuclein(A53T)_upregulated
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062534:fat-P-80_downregulated
      WBPaper00064539:nhr-114(gk849)_downregulated
      WBPaper00064661:lpd-3(ok2138)_upregulated
      WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
      WBPaper00065746:eat-2(ad1113)_downregulated
      WBPaper00065746:tmc-1(rg1003)_upregulated
      WBPaper00065984:pals-17(syb3980)_downregulated
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      cgc4489_group_14
      WBPaper00056330:mrps-5(RNAi)_upregulated
  Map_info: Positive: Positive_clone: Y50D7A Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: III -26.9033
  Method: Gene