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WormBase Tree Display for Gene: WBGene00045419

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Name Class

WBGene00045419SMapS_parentSequenceCHROMOSOME_V
IdentityVersion4
NameCGC_namelsy-12Person_evidenceWBPerson260
Sequence_nameR07B5.9
Molecular_name (35)
Other_namemys-3Person_evidenceWBPerson2693
WBPerson552
WBPerson268
CELE_R07B5.9Accession_evidenceNDBBX284605
Public_namelsy-12
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change118 May 2007 14:42:36WBPerson2970EventCreated
209 Apr 2008 11:18:54WBPerson2970EventAcquires_mergeWBGene00011086
Name_changeSequence_nameR07B5.9
321 May 2010 13:42:20WBPerson2970EventAcquires_mergeWBGene00011085
Name_changeOther_namemys-3
421 May 2010 17:14:23WBPerson1983EventAcquires_mergeWBGene00011700
Acquires_mergeWBGene00011085
WBGene00011086
WBGene00011700
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classlsy
Allele (200)
StrainWBStrain00029379
WBStrain00029380
WBStrain00029484
WBStrain00029537
WBStrain00029547
WBStrain00029584
RNASeq_FPKM (74)
GO_annotation (16)
Ortholog (32)
ParalogWBGene00007029Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00007914Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00010537Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
WBGene00016200Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00018013Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionlsy-12 encodes a histone acetyltransferase; lsy-12 is maternally required for developmental differentiation of ASEL neurons from ASERs, with lsy-12 mutants having double ASERs and no ASELs; lsy-12 is also zygotically required for normal vulval development, locomotion, egg-laying, fecundity, health, and viability of gravid hermaphrodites; lsy-12(ot171) hermaphrodites bag prematurely, are sickly, and have mildly protruding vulvae, while other lsy-12 mutants display egg-laying defects, protruding vulvae, or low brood sizes; on the basis of its phenotype, lsy-12 is expected to act in concert with CEH-36, DIE-1, LIN-49, LSY-2, and lsy-6 during the lateral specification of ASER/ASEL.Paper_evidenceWBPaper00030973
WBPaper00032078
WBPaper00036201
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated25 May 2010 00:00:00
Automated_descriptionPredicted to enable histone H4K16 acetyltransferase activity and transcription coregulator activity. Involved in cell fate specification; maintenance of left/right asymmetry; and positive regulation of gene expression. Predicted to be part of MSL complex.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSR07B5.9a
R07B5.9b
R07B5.9c
R07B5.9d
R07B5.9f
R07B5.9g
R07B5.9h
R07B5.9i
R07B5.9j
R07B5.9k
Corresponding_CDS_historyR07B5.9:wp175
R07B5.9:wp215
R07B5.9a:wp217
R07B5.9c:wp217
R07B5.9d:wp217
R07B5.9e:wp217
R07B5.9e:wp229
Corresponding_transcript (15)
Other_sequenceCJC07250_1
CR12610
CBC10948_1
JO472705.1
CRC10004_1
Associated_feature (18)
Transcription_factorWBTranscriptionFactor000786
Experimental_infoRNAi_result (16)
Expr_patternExpr1029108
Expr1040370
Expr1155114
Expr2013301
Expr2031532
Drives_constructWBCnstr00023226
Construct_productWBCnstr00021795
WBCnstr00023226
Microarray_results (67)
Expression_cluster (149)
InteractionWBInteraction000046040
WBInteraction000500193
WBInteraction000500194
WBInteraction000500195
WBInteraction000539678
Map_infoMapVPosition2.20105Error0.000124
PositivePositive_cloneR07B5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (12)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene