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WormBase Tree Display for Gene: WBGene00010537

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Name Class

WBGene00010537SMapS_parentSequenceK03D10
IdentityVersion2
NameCGC_namemys-2Person_evidenceWBPerson2693
WBPerson552
WBPerson268
Sequence_nameK03D10.3
Molecular_name (12)
Other_nameCELE_K03D10.3Accession_evidenceNDBBX284601
Public_namemys-2
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:51WBPerson1971EventImportedInitial conversion from CDS class of WS125
207 Apr 2008 14:21:37WBPerson2970Name_changeCGC_namemys-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmys
Allele (140)
StrainWBStrain00036975
RNASeq_FPKM (74)
GO_annotation (14)
Contained_in_operonCEOP1731
Ortholog (40)
ParalogWBGene00007914Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
WBGene00045419Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
WBGene00007029Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00016200Caenorhabditis elegansFrom_analysisWormBase-Compara
WBGene00018013Caenorhabditis elegansFrom_analysisWormBase-Compara
Structured_descriptionConcise_descriptionmys-2 encodes a MYST acetyltransferase orthologous to the Drosophila MALES-ABSENT-ON-THE-FIRST (MOF) and CG1894 proteins, the human MOF protein, and the S. cerevisiae SAS2 protein.Paper_evidenceWBPaper00004587
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated08 Jul 2014 00:00:00
Automated_descriptionPredicted to enable histone H4K16 acetyltransferase activity and transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of MSL complex. Expressed in germ line. Human ortholog(s) of this gene implicated in breast cancer and clear cell renal cell carcinoma. Is an ortholog of human KAT8 (lysine acetyltransferase 8).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:4467Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:17933)
DOID:1612Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:17933)
Molecular_infoCorresponding_CDSK03D10.3a
K03D10.3b
K03D10.3c
K03D10.3d
Corresponding_CDS_historyK03D10.3:wp252
Corresponding_transcriptK03D10.3a.1
K03D10.3b.1
K03D10.3c.1
K03D10.3d.1
Other_sequence (526)
Associated_featureWBsf986058
WBsf986059
WBsf986060
WBsf1011188
WBsf218775
Experimental_infoRNAi_result (34)
Expr_patternExpr4088
Expr1024587
Expr1034596
Expr1153528
Expr2013849
Expr2032089
Microarray_results (18)
Expression_cluster (85)
Interaction (18)
Map_infoMapIPosition23.2088Error0.013957
PositivePositive_cloneK03D10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (12)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene