WormBase Tree Display for Gene: WBGene00007914
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| WBGene00007914 | SMap | S_parent | Sequence | C34B7 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | mys-4 | Person_evidence | WBPerson2693 | |||||
| WBPerson552 | |||||||||
| WBPerson268 | |||||||||
| Sequence_name | C34B7.4 | ||||||||
| Molecular_name | C34B7.4 | ||||||||
| C34B7.4.1 | |||||||||
| CE27818 | |||||||||
| Other_name | CELE_C34B7.4 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | mys-4 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 26 May 2004 16:54:48 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of WS125 | ||
| 2 | 07 Apr 2008 14:21:37 | WBPerson2970 | Name_change | CGC_name | mys-4 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | mys | ||||||||
| Allele (36) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (12) | |||||||||
| Contained_in_operon | CEOP1464 | ||||||||
| Ortholog (35) | |||||||||
| Paralog | WBGene00007029 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| WBGene00016200 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| WBGene00010537 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| WormBase-Compara | |||||||||
| WBGene00045419 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00018013 | Caenorhabditis elegans | From_analysis | Panther | ||||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | C34B7.4 encodes a MYST family histone acetyltransferase; based upon sequence similarity, the product of C34B7.4 is predicted to be the enzymatic component of an NuA4-like histone acetyltransferase (HAT) complex that functions in transcriptional activation; C34B7.4 is likely required for regulating gene expression in multiple tissues, as loss of its activity via RNAi results in suppression of ectopic lag-2 reporter expression seen in intestinal tissue in SynMuv B mutants as well as in some suppression of the lin-15AB SynMuv phenotype. | Paper_evidence | WBPaper00013412 | |||||
| WBPaper00027634 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 11 Jun 2007 00:00:00 | ||||||||
| Automated_description | Predicted to enable histone H4K16 acetyltransferase activity and transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription and positive regulation of transcription by RNA polymerase II. Predicted to be part of MSL complex. Human ortholog(s) of this gene implicated in androgen insensitivity syndrome and breast cancer. Is an ortholog of human KAT7 (lysine acetyltransferase 7). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:4674 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17016) | ||||
| DOID:1612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17016) | ||||||
| Molecular_info | Corresponding_CDS | C34B7.4 | |||||||
| Corresponding_transcript | C34B7.4.1 | ||||||||
| Other_sequence (23) | |||||||||
| Associated_feature | WBsf643525 | ||||||||
| WBsf656626 | |||||||||
| WBsf656627 | |||||||||
| WBsf218145 | |||||||||
| WBsf218146 | |||||||||
| WBsf218147 | |||||||||
| Experimental_info | RNAi_result (11) | ||||||||
| Expr_pattern | Expr1017710 | ||||||||
| Expr1033428 | |||||||||
| Expr1145856 | |||||||||
| Expr2013850 | |||||||||
| Expr2032090 | |||||||||
| Drives_construct | WBCnstr00033385 | ||||||||
| Construct_product | WBCnstr00033385 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (122) | |||||||||
| Interaction | WBInteraction000051554 | ||||||||
| WBInteraction000051590 | |||||||||
| WBInteraction000051619 | |||||||||
| WBInteraction000051661 | |||||||||
| WBInteraction000552465 | |||||||||
| WBInteraction000553666 | |||||||||
| WBInteraction000582754 | |||||||||
| Map_info | Map | I | Position | 2.7464 | Error | 0.002289 | |||
| Positive | Positive_clone | C34B7 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00013412 | ||||||||
| WBPaper00027634 | |||||||||
| WBPaper00036007 | |||||||||
| WBPaper00038372 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00042680 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00060474 | |||||||||
| WBPaper00065308 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
