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WormBase Tree Display for Gene: WBGene00045401

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Name Class

WBGene00045401SMapS_parentSequenceT26F2
IdentityVersion2
NameCGC_nameeol-1Paper_evidenceWBPaper00045830
Person_evidenceWBPerson1627
Sequence_nameT26F2.3
Molecular_nameT26F2.3
T26F2.3.1
CE41028
T26F2.3.2
Other_nameCELE_T26F2.3Accession_evidenceNDBBX284605
Public_nameeol-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change127 Apr 2007 09:42:00WBPerson4025EventSplit_fromWBGene00012058
222 Dec 2014 11:59:25WBPerson2970Name_changeCGC_nameeol-1
Split_fromWBGene00012058
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classeol
Allele (35)
Possibly_affected_byWBVar02157243
RNASeq_FPKM (74)
GO_annotation (20)
Ortholog (50)
Paralog (11)
Structured_descriptionConcise_descriptioneol-1 encodes a homolog of vertebrate DXO/Dom3Z, a decapping and exoribonuclease protein that functions in pre-mRNA quality control; in C. elegans, EOL-1 activity is required in the URX sensory neurons for inhibition of olfactory learning; mouse Dom3Z can functionally substitute for C. elegans EOL-1, demonstrating conservation of activity for these proteins; in adult hermaphrodites, an eol-1::gfp promoter fusion is expressed in several head and tail neurons, including URX, AVF, and PQR, and in reproductive tissues.Paper_evidenceWBPaper00045830
Curator_confirmedWBPerson1843
Date_last_updated22 Dec 2014 00:00:00
Automated_descriptionPredicted to enable 5'-3' exonuclease activity; mRNA 5'-diphosphatase activity; and mRNA binding activity. Involved in regulation of olfactory learning. Predicted to be located in cytosol and nucleus. Expressed in AVF; oxygen sensory neurons; and reproductive system.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDST26F2.3
Corresponding_CDS_historyT26F2.3:wp195
T26F2.3:wp215
Corresponding_transcriptT26F2.3.1
T26F2.3.2
Other_sequenceCBC10792_1
Associated_featureWBsf234889
Experimental_infoRNAi_resultWBRNAi00054220Inferred_automaticallyRNAi_primary
WBRNAi00019270Inferred_automaticallyRNAi_primary
Expr_patternExpr12008
Expr15788
Expr1019371
Expr1157766
Expr2011336
Expr2029572
Drives_constructWBCnstr00020068
WBCnstr00020069
WBCnstr00020070
WBCnstr00023236
Construct_productWBCnstr00020068
WBCnstr00023236
WBCnstr00042520
Microarray_results (16)
Expression_cluster (290)
Map_infoMapVPosition5.86927
PositivePositive_cloneT26F2Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00045830
WBPaper00051856
WBPaper00060692
WBPaper00061319
WBPaper00064708
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene