WormBase Tree Display for Gene: WBGene00022727
expand all nodes | collapse all nodes | view schema
| WBGene00022727 | SMap | S_parent | Sequence | ZK381 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | prkl-1 | Person_evidence | WBPerson114 | |||||
| Sequence_name | ZK381.5 | ||||||||
| Molecular_name | ZK381.5a | ||||||||
| ZK381.5a.1 | |||||||||
| CE41743 | |||||||||
| ZK381.5b | |||||||||
| CE41744 | |||||||||
| ZK381.5b.1 | |||||||||
| Other_name | nde-2 | Paper_evidence | WBPaper00049708 | ||||||
| CELE_ZK381.5 | Accession_evidence | NDB | BX284604 | ||||||
| Public_name | prkl-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:06 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 15 Mar 2007 17:00:31 | WBPerson2970 | Name_change | CGC_name | prkl-1 | ||||
| 3 | 02 Aug 2016 10:45:57 | WBPerson2970 | Name_change | Other_name | nde-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | prkl | ||||||||
| Allele (100) | |||||||||
| Strain | WBStrain00030530 | ||||||||
| WBStrain00033022 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00005326 | ||||||||
| 00126723 | |||||||||
| Ortholog (47) | |||||||||
| Paralog | WBGene00004112 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WBGene00015217 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Panther | |||||||||
| Structured_description | Concise_description | prkl-1 encodes a homolog of Drosophila ESPINAS and PRICKLE, and of humanPRICKLE1, PRICKLE2, and LMO6; prkl-1 enables Wnt-directed planar cellpolarity; prkl-1 is required for the fully asymmetrical division of B.aversus B.p cells, though this requirement is quantitatively weak. | Paper_evidence | WBPaper00027345 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 25 Oct 2006 00:00:00 | ||||||||
| Automated_description | Predicted to enable zinc ion binding activity. Expressed in several structures, including QL; egg-laying apparatus; gonad; head; and somatic nervous system. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 1B. Is an ortholog of human PRICKLE2 (prickle planar cell polarity protein 2) and PRICKLE3 (prickle planar cell polarity protein 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0111448 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:17019) | ||||
| Molecular_info | Corresponding_CDS | ZK381.5a | |||||||
| ZK381.5b | |||||||||
| Corresponding_CDS_history | ZK381.5:wp83 | ||||||||
| ZK381.5a:wp183 | |||||||||
| ZK381.5b:wp183 | |||||||||
| Corresponding_transcript | ZK381.5a.1 | ||||||||
| ZK381.5b.1 | |||||||||
| Other_sequence | BMC13568_1 | ||||||||
| JI171960.1 | |||||||||
| BM01268 | |||||||||
| Associated_feature (14) | |||||||||
| Transcription_factor | WBTranscriptionFactor000259 | ||||||||
| Experimental_info | RNAi_result (21) | ||||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00002499 | ||||||||
| WBCnstr00002500 | |||||||||
| WBCnstr00009089 | |||||||||
| WBCnstr00009093 | |||||||||
| WBCnstr00014217 | |||||||||
| WBCnstr00024021 | |||||||||
| Construct_product | WBCnstr00009089 | ||||||||
| WBCnstr00009097 | |||||||||
| WBCnstr00009098 | |||||||||
| WBCnstr00009099 | |||||||||
| WBCnstr00023141 | |||||||||
| WBCnstr00024021 | |||||||||
| Microarray_results (30) | |||||||||
| Expression_cluster (179) | |||||||||
| Interaction (78) | |||||||||
| Map_info | Map | IV | Position | 3.27518 | Error | 0.000766 | |||
| Positive | Positive_clone | ZK381 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (18) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
