Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00022500

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00022500EvidencePaper_evidenceWBPaper00013452
SMapS_parentSequenceZC8
IdentityVersion2
NameCGC_namelfi-1Person_evidenceWBPerson732
Sequence_nameZC8.4
Molecular_name (21)
Other_nameCELE_ZC8.4Accession_evidenceNDBBX284606
Public_namelfi-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:05WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
204 Jun 2004 10:29:58WBPerson1971Name_changeCGC_namelfi-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classlfi
AlleleWBVar00093185Inferred_automaticallyFrom strain object: RB1619
WBVar02139236
WBVar02139237
WBVar02139238
WBVar00296339
WBVar02139239
WBVar02139240
WBVar01830445
WBVar00252836
WBVar01830446
WBVar02046889
WBVar01914207
WBVar02015593
WBVar02015594
WBVar00502658
WBVar00502659
WBVar00502660
WBVar00502661
WBVar00502662
WBVar00502663
WBVar00502664
WBVar00502665
WBVar00502666
WBVar00502667
WBVar00502668
WBVar00502669
WBVar00502670
WBVar00502671
WBVar00502672
WBVar00502673
WBVar00502674
WBVar00078458
WBVar00078459
WBVar00502675
WBVar01144257
WBVar00502676
WBVar00078460
WBVar01144258
WBVar00078461
WBVar00502677
WBVar01144259
WBVar00502678
WBVar00078462
WBVar01144260
WBVar00502679
WBVar00078463
WBVar01144261
WBVar00078464
WBVar01144262
WBVar00502680
WBVar01144263
WBVar00502681
WBVar01144264
WBVar00502682
WBVar02048782
WBVar00502683
WBVar01144265
WBVar00502684
WBVar01144266
WBVar01144267
WBVar00502685
WBVar00502686
WBVar01144268
WBVar01144269
WBVar00502687
WBVar00502688
WBVar01144270
WBVar00502689
WBVar01144271
WBVar00502690
WBVar01144272
WBVar00502691
WBVar01144273
WBVar01144274
WBVar00502692
WBVar00502693
WBVar01144275
WBVar02046370
WBVar00502694
WBVar01144276
WBVar02046371
WBVar01144277
WBVar00502695
WBVar01144278
WBVar02046372
WBVar01819768
WBVar00502696
WBVar01144279
WBVar01819769
WBVar00502697
WBVar00502698
WBVar01819770
WBVar01144280
WBVar01486890
WBVar01897624
WBVar01144281
WBVar01144282
WBVar01486891
WBVar01601712
WBVar01144283
WBVar01144284
WBVar01878574
WBVar01144285
WBVar01144286
WBVar01878575
WBVar01144287
WBVar01878576
WBVar01144288
WBVar01878577
WBVar01878578
WBVar01144289
WBVar01878579
WBVar01144290
WBVar02112213
WBVar01878580
WBVar01144291
WBVar01144292
WBVar01878581
WBVar01878582
WBVar01144293
WBVar01144294
WBVar01878583
WBVar01144295
WBVar01878584
WBVar01878585
WBVar01144296
WBVar01144297
WBVar01878586
WBVar01878587
WBVar01144298
WBVar01878588
WBVar01144299
WBVar01878589
WBVar01144300
WBVar01144301
WBVar01144302
WBVar01144303
WBVar01144304
WBVar01144305
WBVar01144306
WBVar01549547
WBVar01144307
WBVar01549548
WBVar01549549
WBVar01144308
WBVar01549550
WBVar02063645
WBVar01144309
WBVar02063646
WBVar01549551
WBVar01144310
WBVar01144311
WBVar01549552
WBVar02063647
WBVar01144312
WBVar01549553
WBVar01549554
WBVar01801011
WBVar01144313
WBVar01144314
WBVar01144315
WBVar01144316
WBVar01144317
WBVar01144318
WBVar01144319
WBVar01144320
WBVar01144321
WBVar01144322
WBVar01144323
WBVar01144324
WBVar02151170
WBVar01144325
WBVar02001145
WBVar01144326
WBVar01144327
WBVar01144328
WBVar01144329
WBVar01144330
WBVar01144331
WBVar01144332
WBVar01144333
WBVar01144334
WBVar01144335
WBVar01144336
WBVar01144337
WBVar01144338
WBVar01945224
WBVar01144339
WBVar01144340
WBVar01945225
WBVar01144341
WBVar01945226
WBVar01144342
WBVar01144343
WBVar01144344
WBVar01144345
WBVar01144346
WBVar01144347
WBVar01144348
WBVar01144349
WBVar01494870
WBVar01144350
WBVar01144351
WBVar01144352
WBVar01144353
WBVar01144354
WBVar01144355
WBVar01144356
WBVar01144357
WBVar01144358
WBVar01144359
WBVar01144360
WBVar01144361
WBVar01758210
WBVar01144362
WBVar01144363
WBVar01758211
WBVar01144364
WBVar01758212
WBVar01144365
WBVar01758213
WBVar01758214
WBVar01144366
WBVar01144367
WBVar01980609
WBVar01144368
WBVar01782207
WBVar01144369
WBVar01144370
WBVar01144371
WBVar01144372
WBVar01144373
WBVar01144374
WBVar01144375
WBVar01144376
WBVar01144377
WBVar01468740
WBVar01144378
WBVar01144379
WBVar01144380
WBVar01144381
WBVar02027044
WBVar01144382
WBVar01144383
WBVar01144384
WBVar00260928
WBVar01144385
WBVar01144386
WBVar01144387
WBVar01825221
WBVar01144388
WBVar01500067
StrainWBStrain00032313
RNASeq_FPKM (74)
GO_annotation00023076
00023077
Ortholog (43)
ParalogWBGene00018051Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptionlfi-1 encodes, by alternative splicing, at least four isoforms of alarge coiled-coil protein paralogous to F35D11.11, and possiblyorthologous to rootletin (the structural protein comprising ciliaryrootlets); LFI-1 is also homologous to the Parascaris univalens MitoticAntigen, PUMA1; LFI-1 was initially identified in yeast two-hybrid screens for proteins that interact with the coiled-coil protein LIN-5, which is essential for proper spindle positioning and chromosome segregation; antibody staining reveals that, in embryos, LFI-1 is expressed in metaphase cells in a diffuse area surrounding the kinetochore microtubules and overlapping with LIN-5 localization; in interphase cells, LFI-1 localizes to the nucleus and remains in the nuclear region even after nuclear envelope breakdown; as loss of lfi-1 activity, or the combined activities of lfi-1 and a related gene, F35D11.11, by RNAi results in no obvious defects, the precise role of LFI-1 in development is not yet known.Paper_evidenceWBPaper00024244
WBPaper00029004
WBPaper00029016
Curator_confirmedWBPerson1843
Date_last_updated07 Feb 2007 00:00:00
Automated_descriptionLocated in kinetochore microtubule and nucleus. Is an ortholog of human CROCC (ciliary rootlet coiled-coil, rootletin).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelEFO:0009151Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1859)
Molecular_infoCorresponding_CDSZC8.4a
ZC8.4d
ZC8.4e
ZC8.4f
ZC8.4g
ZC8.4h
Corresponding_CDS_historyZC8.4b:wp145
ZC8.4b:wp272
ZC8.4c:wp145
ZC8.4d:wp272
ZC8.4e:wp272
Corresponding_transcriptZC8.4a.1
ZC8.4a.2
ZC8.4a.3
ZC8.4a.4
ZC8.4d.1
ZC8.4e.1
ZC8.4f.1
ZC8.4g.1
ZC8.4h.1
Other_sequence (219)
Associated_featureWBsf648060
WBsf648061
WBsf978486
WBsf1005147
WBsf1005148
WBsf1022896
WBsf235646
WBsf235647
WBsf235648
Transcription_factorWBTranscriptionFactor000405
Experimental_infoRNAi_resultWBRNAi00021759Inferred_automaticallyRNAi_primary
WBRNAi00002294Inferred_automaticallyRNAi_primary
WBRNAi00062893Inferred_automaticallyRNAi_primary
WBRNAi00038104Inferred_automaticallyRNAi_primary
WBRNAi00059021Inferred_automaticallyRNAi_primary
WBRNAi00017162Inferred_automaticallyRNAi_primary
WBRNAi00070889Inferred_automaticallyRNAi_primary
WBRNAi00034411Inferred_automaticallyRNAi_primary
WBRNAi00062898Inferred_automaticallyRNAi_primary
WBRNAi00070888Inferred_automaticallyRNAi_primary
Expr_patternExpr2936
Expr1013576
Expr1039943
Expr1162452
Expr2013090
Expr2031322
Drives_constructWBCnstr00024200
Construct_productWBCnstr00024200
WBCnstr00038856
AntibodyWBAntibody00000895
WBAntibody00001192
Microarray_results (48)
Expression_cluster (263)
Interaction (51)
Map_infoMapXPosition-6.19862Error0.000328
PositivePositive_cloneZC8Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00010599
WBPaper00018632
WBPaper00023417
WBPaper00024244
WBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene