WormBase Tree Display for Gene: WBGene00022495

WBGene00022495 SMap: S_parent: Sequence: Y119D3B
  Identity: Version: 3
    Name: CGC_name: fbxa-78 Person_evidence: WBPerson655
      Sequence_name: Y119D3B.19
      Molecular_name: Y119D3B.19
        Y119D3B.19.1
        CE15008
      Other_name: CELE_Y119D3B.19 Accession_evidence: NDB BX284603
      Public_name: fbxa-78
    DB_info: Database: AceView gene 3C346
        WormQTL gene WBGene00022495
        WormFlux gene WBGene00022495
        NDB locus_tag CELE_Y119D3B.19
        NCBI gene 191046
        RefSeq protein NM_064957.7
        TREEFAM TREEFAM_ID TF322006
        TrEMBL UniProtAcc G5EDF8
        UniProt_GCRP UniProtAcc G5EDF8
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:05 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 12 Dec 2005 15:18:56 WBPerson2970 Name_change: CGC_name: fbxa-78
        3 10 Jun 2014 12:12:12 WBPerson1983 Event: Acquires_merge: WBGene00043944
      Acquires_merge: WBGene00043944
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: fbxa
    Allele (33)
    RNASeq_FPKM (74)
    Ortholog: WBGene00042835 Caenorhabditis briggsae From_analysis: Inparanoid_8
      WBGene00122765 Caenorhabditis japonica From_analysis: Inparanoid_8
      CSP28.g15362 Caenorhabditis panamensis From_analysis: WormBase-Compara
      chrIII_pilon.g6909 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00065925 Caenorhabditis remanei From_analysis: WormBase-Compara
    Paralog (199)
    Structured_description: Concise_description: fbxa-78 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; FBXA-78 also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction. Paper_evidence: WBPaper00012854
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enriched in intestine based on RNA-seq studies. Is affected by several genes including daf-16; daf-2; and daf-12 based on microarray and RNA-seq studies. Is affected by fourteen chemicals including hydrogen sulfide; methylmercury hydroxide; and sesamin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: F-box-like domain superfamily; FTH domain; F-box domain; Domain of unknown function DUF38/FTH, Caenorhabditis species; and F-box A protein FB224. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y119D3B.19
    Corresponding_transcript: Y119D3B.19.1
    Associated_feature: WBsf991260
      WBsf991261
      WBsf226199
  Experimental_info: RNAi_result (11)
    Expr_pattern: Expr1026821
      Expr1159018
      Expr2011576
      Expr2029816
    Drives_construct: WBCnstr00024204
    Construct_product: WBCnstr00024204
    Microarray_results (23)
    Expression_cluster: WBPaper00027339:daf-12(rh273)_downregulated
      WBPaper00031040:TGF-beta_adult_upregulated
      WBPaper00038438:E.faecalis_24hr_upregulated_TilingArray
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040285:H2S_24hr_upregulated
      WBPaper00043945:MeHg_upregulated
      WBPaper00045050:csr-1(hypomorph)_upregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00048971:daf-16(mgDf50)_downregulated_L1
      WBPaper00049942:HeatShock_upregulated_hsf-1(+)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050080:rbr-2(tm3141)_upregulated
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050843:sesamin_upregulated
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:intestine_enriched
      WBPaper00050990:intestine_expressed
      WBPaper00051257:Levamisole_downregulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053020:sta-1(ok587)_upregulated
      WBPaper00053388:dauer_regulated_Cluster3
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055827:daf-2(e1370)_upregulated
      WBPaper00055897:heat-shock_upregulated
      WBPaper00056167:ifo-1(kc2)_downregulated
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056275:P.aeruginosa_upregulated_atf-7(qd22qd130)_dependent
      WBPaper00056275:P.aeruginosa_upregulated_pmk-1(km25)_dependent
      WBPaper00056293:rpl-5(0)-rpl-33(0)_upregulated
      WBPaper00056617:adr-1_upregulated_embryo_transcript
      WBPaper00057068:ints-4(RNAi)_upregulated_Cadmium
      WBPaper00058598:spn-4(tm291)_downregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00058725:sftb-1(cer39)_upregulated
      WBPaper00058955:heatshock_upregulated_CE
      WBPaper00059664:srbc-48(ac23)_upregulated
      WBPaper00059987:Wounding_downregulated
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060703:nas-38(ok3407)_downregulated
      WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
      WBPaper00061081:skpo-1(ok1640)_downregulated_OP50
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061530:nhr-49(e2144)_downregulated
      WBPaper00061952:daf-18(yh1)_downregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:daf-16(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062497:xpf-1(tm2842)_upregulated
      WBPaper00062520:qui-1(db104)_downregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065581:hpk-1(pk1393)_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00032948:StarveUp2
      WBPaper00035227:heat_shock_regulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036286:Pattern_D
      WBPaper00036383:ash-2_Day8_regulated
      WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated
      WBPaper00037695:WC_5-day
      WBPaper00038172:tax-6null_up_regulated
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00038231:Cry5B_2-fold_downregulated
      WBPaper00038304:octr-1_regulated
      WBPaper00039866:ClassComp_daf-19_downregulated
      WBPaper00039866:SAM_daf-19_downregulated
      WBPaper00040184:hcf-1nc_sir-2.1up_daf-2up
      WBPaper00040426:CYD-1_CDK-4_downregulated
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_developing
      WBPaper00040858:eQTL_regulated_juvenile
      WBPaper00040858:eQTL_regulated_old
      WBPaper00041002:HF_3d_0.2mM_Up
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_3h
      WBPaper00042236:flcn-1(ok975)_upregulated
      WBPaper00044535:male_downregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00047070:N2_starvation_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00049311:AgNO3_regulated
      WBPaper00050520:lagr-1(gk327);hyl-1(ok976)_downregulated
      WBPaper00053236:daf-16(mgDF50)_regulated_Starved
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053550:daf-19(m86)_downregulated_3-fold-embryo
      WBPaper00053550:daf-19(m86)_downregulated_L1
    Interaction: WBInteraction000504152
  Map_info (3)
  Reference: WBPaper00041771
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
    [140610 pad] Gene was missing Acquires_merge Event history data so inferred from Acquires_merge tag.
  Method: Gene