Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00021948

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00021948SMapS_parentSequenceY55F3C
IdentityVersion3
NameCGC_namekvs-5Person_evidenceWBPerson260
WBPerson145
Sequence_nameY55F3C.3
Molecular_name (18)
Other_nameY55F3C.fCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
Y55F3C.eCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
CELE_Y55F3C.3Accession_evidenceNDBBX284604
Public_namekvs-5
DB_infoDatabaseAceViewgene4B505
WormQTLgeneWBGene00021948
WormFluxgeneWBGene00021948
NDBlocus_tagCELE_Y55F3C.3
PanthergeneCAEEL|WormBase=WBGene00021948|UniProtKB=U4PLR3
familyPTHR11537
NCBIgene176899
RefSeqproteinNM_067577.8
NM_001307395.4
NM_001307396.4
NM_001307394.3
NM_001307393.3
NM_001307392.3
TrEMBLUniProtAccU4PE60
U4PR20
U4PBB7
U4PAX5
Q95XV8
U4PLR3
UniProt_GCRPUniProtAccU4PLR3
OMIMgene600397
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:05WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
229 Jul 2011 16:30:08WBPerson2970Name_changeCGC_namekvs-5
304 Sep 2013 14:28:38WBPerson4025EventAcquires_mergeWBGene00043706
Acquires_mergeWBGene00043706
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classkvs
Allele (372)
StrainWBStrain00007651
RNASeq_FPKM (74)
GO_annotation (22)
Ortholog (51)
Paralog (13)
Structured_descriptionAutomated_descriptionPredicted to enable delayed rectifier potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Located in plasma membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 26. Is an ortholog of human KCNF1 (potassium voltage-gated channel modifier subfamily F member 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0080461Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6231)
DOID:1826Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6231)
Molecular_infoCorresponding_CDSY55F3C.3a
Y55F3C.3c
Y55F3C.3d
Y55F3C.3e
Y55F3C.3f
Y55F3C.3g
Corresponding_CDS_historyY55F3C.3:wp175
Y55F3C.3b:wp274
Corresponding_transcriptY55F3C.3a.1
Y55F3C.3c.1
Y55F3C.3d.1
Y55F3C.3e.1
Y55F3C.3f.1
Y55F3C.3g.1
Other_sequence (19)
Associated_feature (27)
Experimental_infoRNAi_resultWBRNAi00021056Inferred_automaticallyRNAi_primary
WBRNAi00002374Inferred_automaticallyRNAi_primary
WBRNAi00057555Inferred_automaticallyRNAi_primary
WBRNAi00021057Inferred_automaticallyRNAi_primary
Expr_patternExpr9462
Expr1016026
Expr1017500
Expr1039655
Expr1160988
Expr1160989
Expr2012988
Expr2031220
Drives_constructWBCnstr00024396
Construct_productWBCnstr00014027
WBCnstr00024396
Microarray_results (44)
Expression_clusterWBPaper00033065:cyc-1(RNAi)_downregulated
WBPaper00036375:enriched_in_PVD_OLL
WBPaper00037950:all-neurons_L2-larva_expressed
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:bodywall-muscle_larva_enriched
WBPaper00037950:bodywall-muscle_larva_SelectivelyEnriched
WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:dopaminergic-neurons_larva_enriched
WBPaper00037950:dopaminergic-neurons_larva_SelectivelyEnriched
WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
WBPaper00038438:S.marcescens_24hr_downregulated_RNAseq
WBPaper00040134:nhr-49(RNAi)_regulated_protein
WBPaper00042477:rsr-2(RNAi)_downregulated_TilingArray
WBPaper00042561:smgl-1(RNAi)_upregulated
WBPaper00044578:reduced-humidity_downregulated_microarray
WBPaper00044736:flat_dev_expression
WBPaper00044786:emr-1(gk119)_upregulated
WBPaper00045417:128Q-huntingtin_upreglated
WBPaper00045420:fertilization_downregulated_transcript
WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
WBPaper00047132:skn-1(RNAi)_downregulated
WBPaper00048923:Aging_regulated
WBPaper00048971:daf-16(mgDf50)_upregulated_L1
WBPaper00048988:neuron_expressed
WBPaper00049217:DAF-16_downregulated
WBPaper00049290:rsks-1(sv31)_upregulated
WBPaper00049377:MWCNT_upregulated
WBPaper00049545:jmjd-3.1(+)_upregulated
WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
WBPaper00049635:dop-1(vs100)_downregulated
WBPaper00049920:hyl-2(tm2031)_upregulated
WBPaper00049942:HeatShock_upregulated_hsf-1(+)
WBPaper00050163:chd-3(eh4);let-418(RNAi)_upregulated_24-cell-embryo
WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
WBPaper00050488:20C_vs_25C_regulated_N2_adult
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:daf-2(e1370)_vs_daf-2(e1370);mir-34(gk437)_regulated_dauer_25C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_adult_25C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:mir-34(OverExpression)_vs_N2_regulated_adult_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
WBPaper00050726:OsmoticStress_regulated_NoFood
WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
WBPaper00050990:body-muscle_expressed
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:NMDA-neuron_expressed
WBPaper00051245:body-wall-muscle_cytoplasm_expressed
WBPaper00051245:body-wall-muscle_nucleus_expressed
WBPaper00051404:alg-1(gk214)_upregulated
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053020:sid-3(ok973)_upregulated
WBPaper00053184:sma-2(rax5)_downregulated
WBPaper00053295:lin-22(icb38)_upregulated
WBPaper00053295:lin-22(ot267)_upregulated
WBPaper00053295:lin-22(ot269)_upregulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053388:dauer_regulated_Cluster4
WBPaper00053810:daf-2(e1370)_downregulated
WBPaper00054192:cold-shock_upregulated
WBPaper00054493:hpl-2(tm1489)_upregulated
WBPaper00054758:alg-1(gk204)_upregulated
WBPaper00055354:Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin_downregulated
WBPaper00055354:Rifampicin-Allantoin_downregulated
WBPaper00055386:daf-2(e1370)_downregulated
WBPaper00055482:pmt-2(RNAi)_upregulated
WBPaper00055482:Tunicamycin_downregulated
WBPaper00055971:nhl-2(ok818)_25C_downregulated
WBPaper00056034:pals-22(jy3)_upregulated
WBPaper00056161:male_enriched_siRNA
WBPaper00056275:P.aeruginosa_downregulated
WBPaper00056275:P.aeruginosa_downregulated_atf-7(qd22qd130)_dependent
WBPaper00056275:P.aeruginosa_downregulated_pmk-1(km25)_dependent
WBPaper00056443:sek-1(km4)_upregulated
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00058598:mex-1(or286)_upregulated
WBPaper00058598:mex-3(eu149)_upregulated
WBPaper00058598:spn-4(tm291)_upregulated
WBPaper00058725:sftb-1(cer6)_downregulated
WBPaper00058725:sftb-1(cer6)_upregulated
WBPaper00059566:wdr-23(mac32)_upregulated
WBPaper00059605:mut-16(pk710)_upregulated
WBPaper00059609:malt-1_ilc-17.1_nfki-1_downregulated
WBPaper00059664:srbc-48(ac23)_upregulated
WBPaper00059754:C.neoformans_H99_upregulated
WBPaper00059824:rnp-6(dh1127)_regulated_OP50
WBPaper00060084:cco-1(RNAi)_downregulated_lin-40(yth27)
WBPaper00060084:cco-1(RNAi)_downregulated_N2
WBPaper00060358:B.thuringiensis_non-pathogen_regulated_N2
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060445:nfki-1(cer1)_downregulated_L4
WBPaper00060459:bcat-1(RNAi)_upregulated
WBPaper00060526:plp-1(ok2155)_upregulated
WBPaper00060661:sensory-neuron_enriched
WBPaper00060683:hlh-11(ko1)_upregulated
WBPaper00060703:nas-38(ok3407)_upregulated
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00061007:S.aquatilis_upregulated
WBPaper00061040:eat-2(ad1116)_upregulated
WBPaper00061040:FW1256_upregulated
WBPaper00061340:BWM_anterior
WBPaper00061424:Diet_MYb120_upregulated
WBPaper00061479:hda-1(ne4752)_upregulated
WBPaper00061527:rgs-2_11061-pde-1
WBPaper00061527:srj-42-srw-113
WBPaper00061651:PQR_enriched
WBPaper00061651:PVN_enriched
WBPaper00061753:csr-1(tor159)_downregulated_25C
WBPaper00061902:camt-1(ok515)_regulated_URX-AQR-PQR
WBPaper00061995:mter-4(syb3662syb3403)_downregulated
WBPaper00062103:neuron_enriched
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062193:daf-16(RNAi)_upregulated
WBPaper00062193:skn-1(RNAi)_downregulated
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00062345:bortezomib_4h_downregulated_N2
WBPaper00062345:bortezomib_4h_downregulated_zip-1(jy13)
WBPaper00062440:crh-1(n3315)_upregulated
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
WBPaper00064156:lbp-3(overexpress)_upregulated
WBPaper00064494:postdauer_upregulated_AWA
WBPaper00064532:pals-25(icb98)_downregulated
WBPaper00064632:daf-2(e1370)_downregulated_intestine
WBPaper00064769:him-17(me24)_upregulated
WBPaper00064871:PA14_downregulated_AWA
WBPaper00064952:Day10_vs_L4_downregulated_25C
WBPaper00065096:25C_vs_20C_downregulated
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065120:body-muscle-transcriptome
WBPaper00065149:lin-52(n771)_downregulated
WBPaper00065258:anchor-cell_depleted
WBPaper00065331:100nM-ivermectin_upregulated
WBPaper00065373:Cisplatin_downregulated_WT
WBPaper00065373:sek-1(km4)_downregulated_cisplatin
WBPaper00065373:sek-1(km4)_downregulated_Ref
WBPaper00065581:hpk-1(pk1393)_upregulated
WBPaper00065623:72
WBPaper00065835:Day11_vs_Day1_downregulated
WBPaper00065841:23_0
WBPaper00065841:35_0
WBPaper00065841:36_2
WBPaper00065841:49_0
WBPaper00065841:51_0
WBPaper00065841:51_1
WBPaper00065841:97_0
WBPaper00065841:107_0
WBPaper00065841:111_0
WBPaper00065841:119_0
WBPaper00065841:125_0
WBPaper00065975:P-body_vs_WholeAnimal_depleted
WBPaper00065993:glp-1(e2141)_upregulated
WBPaper00066232:ash-2(RNAi)_downregulated_WT
cgc4386_cluster_5_6
cgc4489_group_15
WBPaper00026929:Resveratrol_regulated_daf-16
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00031003:0hr_muscle_enriched
WBPaper00031003:total_muscle_enriched
WBPaper00031252:AIN-1_IP_enriched
WBPaper00031832:slr-2_regulated
WBPaper00036286:Pattern_I
WBPaper00040184:hcf-1down_sir-2.1down_daf-2down
WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
WBPaper00041906:I-3690_vs_OP50_3d
WBPaper00041939:control_vs_EtBr-exposed_51h
WBPaper00045673:colistin_upregulated
WBPaper00047070:N2_UV_upregulated
WBPaper00048989:eat-2(ad465)_downregulated_in-DMSO
WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
WBPaper00048989:N2_rapamycin_upregulated
[cgc5376]:let-60(G12V)-regulated_genes
[cgc5767]:expression_class_M
[cgc5767]:expression_class_SM
[cgc6390]:male_sex-enriched
InteractionWBInteraction000112836
WBInteraction000112839
WBInteraction000112840
WBInteraction000162561
WBInteraction000167519
WBInteraction000170122
WBInteraction000293558
WBInteraction000469834
WBInteraction000472696
Map_infoMapIVPosition-23.571Error0.008513
PositivePositive_cloneY55F3CInferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038444
WBPaper00038491
WBPaper00055090
WBPaper00064898
WBPaper00065331
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene