WormBase Tree Display for Gene: WBGene00020169

WBGene00020169 SMap: S_parent: Sequence: T02G5
  Identity: Version: 2
    Name: CGC_name: mmaa-1 Paper_evidence: WBPaper00027754
      Sequence_name: T02G5.13
      Molecular_name: T02G5.13a
        T02G5.13a.1
        CE31822
        T02G5.13b
        CE04865
        T02G5.13b.1
        T02G5.13b.2
      Other_name: CELE_T02G5.13 Accession_evidence: NDB BX284602
      Public_name: mmaa-1
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:02 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 02 Aug 2006 11:39:27 WBPerson2970 Name_change: CGC_name: mmaa-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: mmaa
    Allele (19)
    Strain: WBStrain00032611
      WBStrain00036947
    RNASeq_FPKM (74)
    GO_annotation: 00074214
      00074215
      00074216
      00074217
      00074218
      00074219
      00074220
      00074221
      00124872
      00124873
    Contained_in_operon: CEOP2288
    Ortholog (31)
    Paralog: WBGene00014202 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable GTPase activity. Predicted to be located in cytoplasm. Used to study methylmalonic acidemia. Human ortholog(s) of this gene implicated in methylmalonic acidemia cblA type. Is an ortholog of human MMAA (metabolism of cobalamin associated A). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Experimental_model: DOID:14749 Homo sapiens Paper_evidence: WBPaper00027754
          Curator_confirmed: WBPerson324
          Date_last_updated: 19 Apr 2013 00:00:00
    Potential_model: DOID:0060742 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:18871)
  Models_disease_in_annotation: WBDOannot00000160
  Molecular_info: Corresponding_CDS: T02G5.13a
      T02G5.13b
    Corresponding_CDS_history: T02G5.13:wp84
      T02G5.13:wp127
    Corresponding_transcript: T02G5.13a.1
      T02G5.13b.1
      T02G5.13b.2
    Other_sequence (46)
    Associated_feature: WBsf223291
      WBsf223292
  Experimental_info: RNAi_result: WBRNAi00035066 Inferred_automatically: RNAi_primary
      WBRNAi00018029 Inferred_automatically: RNAi_primary
      WBRNAi00026166 Inferred_automatically: RNAi_primary
      WBRNAi00052224 Inferred_automatically: RNAi_primary
      WBRNAi00018033 Inferred_automatically: RNAi_primary
      WBRNAi00026165 Inferred_automatically: RNAi_primary
      WBRNAi00078224 Inferred_automatically: RNAi_primary
      WBRNAi00027452 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1017099
      Expr1038772
      Expr1155855
      Expr2013624
      Expr2031858
    Drives_construct: WBCnstr00025327
    Construct_product: WBCnstr00025327
    Microarray_results (27)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00035073:mitochondria_protein
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00044426:rotenone_24h_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_downregulated_Day5
      WBPaper00044746:aging_downregulated_HeatShock
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00048785:heat-shock_downregulated
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050370:dpy-21(e428)_L3_downregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00050990:seam_expressed
      WBPaper00051039:ash-2(RNAi)_regulated_intestine
      WBPaper00051039:germline_enriched
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053295:lin-22(icb38)_downregulated
      WBPaper00053295:lin-22(ot267)_downregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053308:SMG-2_associated_NMD(-)_unaltered_ClassII
      WBPaper00053792:Ochrobactrum_downregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053814:15C_downregulated_OP50
      WBPaper00055354:Metformin_downregulated
      WBPaper00055354:Psora-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00058725:sftb-1(cer6)_downregulated
      WBPaper00058725:sftb-1(cer39)_downregulated
      WBPaper00058948:PA14_upregulated
      WBPaper00059328:mrps-5(RNAi)_upregulated_mRNA
      WBPaper00059605:MUT-16_interacting
      WBPaper00059816:crh-1(n3315)_downrgulated
      WBPaper00059895:wounding_downregulated
      WBPaper00059987:Wounding_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061479:HDA-1_interacting_protein
      WBPaper00061527:D1007.4-F33G12.2
      WBPaper00061800:miR-85(n4117)_upregulated_20C
      WBPaper00062293:isp-1(qm150)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062554:MAGU-2_interacting
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064107:lin-35(n745)_downregulated
      WBPaper00064539:nhr-114(gk849)_downregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00066062:xrep-4(lax137)_upregulated
      cgc4386_cluster_1_5
      cgc4489_group_2
      cgc4489_group_4
      WBPaper00005124:progesterone_10-7M_regulated
      WBPaper00025032:cluster_1
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00031003:hlh_1_enriched
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00031252:AIN-2_IP_enriched
      WBPaper00031832:slr-2_regulated
      WBPaper00032165:differentially_expressed_with_age_medoid_5
      WBPaper00034739:N2lessDR1350
      WBPaper00035084:embryo_enriched_AIN-2_IP
      WBPaper00035084:L1_enriched_AIN-2_IP
      WBPaper00035084:L2_enriched_AIN-2_IP
      WBPaper00035084:L3_enriched_AIN-2_IP
      WBPaper00035560:ahr-1_downregulated
      WBPaper00035905:FBF-1_Associated
      WBPaper00036286:Pattern_G
      WBPaper00037113:Diazinon_16C_regulated
      WBPaper00037147:heatshock_upregulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040858:eQTL_regulated_old
      WBPaper00040858:eQTL_regulated_reproductive
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_S.marcescens_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00045263:isp-1(qm150)_upregulated
      WBPaper00045263:nuo-6(qm200)_upregulated
      WBPaper00048989:N2_rapamycin_downregulated
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00055435:AuNPs_downregulated
      WBPaper00055435:MUA-AuNP-0.5_downregulated
      WBPaper00055435:MUA-AuNP-3_downregulated
      [cgc5767]:cluster_1
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_MD_pd(53_min)
      [cgc5767]:expression_class_SM
      [cgc5767]:expression_class_SMD
      [cgc6390]:herm_sex-enriched
    Interaction (38)
  Map_info: Map: II Position: 0.493742 Error: 0.000225
    Positive: Positive_clone: T02G5 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00027754
    WBPaper00038491
    WBPaper00041771
    WBPaper00045654
    WBPaper00049828
    WBPaper00049923
    WBPaper00055090
    WBPaper00061547
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene