WormBase Tree Display for Gene: WBGene00020016

WBGene00020016 SMap: S_parent: Sequence: R11G11
  Identity: Version: 2
    Name: CGC_name: lipl-3 Person_evidence: WBPerson3759
            WBPerson7490
            WBPerson545
      Sequence_name: R11G11.14
      Molecular_name: R11G11.14
        R11G11.14.1
        CE28762
      Other_name: CELE_R11G11.14 Accession_evidence: NDB BX284605
      Public_name: lipl-3
    DB_info: Database (12)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:02 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 19 Jul 2010 13:43:13 WBPerson2970 Name_change: CGC_name: lipl-3
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: lipl
    Allele (186)
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog (64)
    Paralog: WBGene00008510 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00009773 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00010062 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00013050 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00019376 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
      WBGene00022642 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00021963 Caenorhabditis elegans From_analysis: TreeFam
            Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable hydrolase activity, acting on ester bonds. Involved in lipid catabolic process. Located in lysosome. Human ortholog(s) of this gene implicated in Wolman disease; autosomal recessive congenital ichthyosis 8; and cholesterol ester storage disease. Is an ortholog of several human genes including LIPA (lipase A, lysosomal acid type); LIPF (lipase F, gastric type); and LIPJ (lipase family member J). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080217 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6617)
      DOID:14502 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6617)
      DOID:14497 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:6617)
      DOID:0060717 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:23452)
  Molecular_info: Corresponding_CDS: R11G11.14
    Corresponding_transcript: R11G11.14.1
    Other_sequence (133)
    Associated_feature: WBsf233272
  Experimental_info: RNAi_result: WBRNAi00017769 Inferred_automatically: RNAi_primary
      WBRNAi00102886 Inferred_automatically: RNAi_primary
      WBRNAi00115885 Inferred_automatically: RNAi_primary
      WBRNAi00001388 Inferred_automatically: RNAi_primary
      WBRNAi00034869 Inferred_automatically: RNAi_primary
      WBRNAi00051811 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1019660
      Expr1155472
    Drives_construct: WBCnstr00017678
      WBCnstr00025429
    Construct_product: WBCnstr00025429
    Microarray_results (18)
    Expression_cluster (218)
    Interaction: WBInteraction000104178
      WBInteraction000104179
      WBInteraction000135291
      WBInteraction000213132
      WBInteraction000237955
      WBInteraction000245133
      WBInteraction000253478
      WBInteraction000253809
      WBInteraction000256077
      WBInteraction000265292
      WBInteraction000286458
      WBInteraction000291732
      WBInteraction000294268
      WBInteraction000304792
      WBInteraction000305210
      WBInteraction000317554
      WBInteraction000317591
      WBInteraction000317993
      WBInteraction000318517
      WBInteraction000322650
      WBInteraction000324255
      WBInteraction000329303
      WBInteraction000330431
      WBInteraction000332467
      WBInteraction000337865
      WBInteraction000342239
      WBInteraction000343506
      WBInteraction000345378
      WBInteraction000346070
      WBInteraction000347441
      WBInteraction000348610
      WBInteraction000349580
      WBInteraction000350168
      WBInteraction000352117
      WBInteraction000355454
      WBInteraction000357637
      WBInteraction000359335
      WBInteraction000366466
      WBInteraction000376765
      WBInteraction000378469
      WBInteraction000378470
      WBInteraction000381578
      WBInteraction000382933
      WBInteraction000386359
      WBInteraction000389994
      WBInteraction000391675
      WBInteraction000392222
      WBInteraction000392915
      WBInteraction000397118
      WBInteraction000399550
      WBInteraction000404237
      WBInteraction000404260
      WBInteraction000406608
      WBInteraction000410640
      WBInteraction000412048
      WBInteraction000413491
      WBInteraction000417669
      WBInteraction000421104
      WBInteraction000426518
      WBInteraction000433485
      WBInteraction000434715
      WBInteraction000435702
      WBInteraction000436662
      WBInteraction000440226
      WBInteraction000443473
      WBInteraction000444726
      WBInteraction000446903
      WBInteraction000449250
      WBInteraction000452060
      WBInteraction000452798
      WBInteraction000456349
      WBInteraction000457693
      WBInteraction000460989
      WBInteraction000465476
      WBInteraction000472873
      WBInteraction000473557
      WBInteraction000520068
      WBInteraction000520073
  Map_info: Map: V Position: -19.9825
    Positive: Positive_clone: R11G11 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (12)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene