WormBase Tree Display for Gene: WBGene00019327

WBGene00019327 SMap: S_parent: Sequence: K02F3
  Identity: Version: 2
    Name: CGC_name: zip-2 Person_evidence: WBPerson1997
            WBPerson460
      Sequence_name: K02F3.4
      Molecular_name (5)
      Other_name: CELE_K02F3.4 Accession_evidence: NDB BX284603
      Public_name: zip-2
    DB_info: Database: AceView gene 3B453
        WormQTL gene WBGene00019327
        WormFlux gene WBGene00019327
        NDB locus_tag CELE_K02F3.4
        Panther gene CAEEL|WormBase=WBGene00019327|UniProtKB=Q21148
          family PTHR23334
        NCBI gene 175240
        RefSeq protein NM_001384015.2
        SwissProt UniProtAcc Q21148
        TREEFAM TREEFAM_ID TF317134
        UniProt_GCRP UniProtAcc Q21148
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:01 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 18 Jul 2005 13:34:00 WBPerson2970 Name_change: CGC_name: zip-2
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: zip
    Allele (51)
    Strain: WBStrain00037649
    RNASeq_FPKM (74)
    GO_annotation (25)
    Ortholog (23)
    Paralog: WBGene00016754 Caenorhabditis elegans From_analysis: Panther
      WBGene00016997 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00017755 Caenorhabditis elegans From_analysis: Panther
      WBGene00021552 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: zip-2 encodes a bZIP transcription factor; ZIP-2 activity is required for regulating one branch of the immune response pathway that responds to infection by virulent strains of the bacterial pathogen Pseudomonas aeruginosa; specifically, ZIP-2 is required for inducing expression of a subset of infection response genes, including irg-1 and irg-2, and for full resistance to P. aeruginosa infection. Paper_evidence: WBPaper00027309
            WBPaper00035891
          Curator_confirmed: WBPerson1843
          Date_last_updated: 08 Feb 2010 00:00:00
      Automated_description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in defense response to bacterium and positive regulation of macromolecule biosynthetic process. Predicted to be located in nucleus. Expressed in pharynx. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Modifies_disease: DOID:14330
  Modifies_disease_in_annotation: WBDOannot00000499
  Molecular_info: Corresponding_CDS: K02F3.4
    Corresponding_transcript: K02F3.4.1
      K02F3.4.2
      K02F3.4.3
    Other_sequence (25)
    Associated_feature (16)
    Gene_product_binds (249)
    Transcription_factor: WBTranscriptionFactor000223
  Experimental_info (9)
  Map_info: Map: III Position: -25.7689
    Positive: Positive_clone: K02F3 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference (32)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
    [200811 gw3] Modified Map position as it was a reverse physical that could not be fixed by automated methods. (-25.7711)
  Method: Gene