WormBase Tree Display for Gene: WBGene00018643

WBGene00018643 SMap: S_parent: Sequence: F49F1
  Identity: Version: 2
    Name: CGC_name: drd-50 Person_evidence: WBPerson10050
      Sequence_name: F49F1.1
      Molecular_name: F49F1.1
        F49F1.1.1
        CE17084
      Other_name: CELE_F49F1.1 Accession_evidence: NDB BX284604
      Public_name: drd-50
    DB_info: Database: AceView gene 4E883
        WormQTL gene WBGene00018643
        WormFlux gene WBGene00018643
        NDB locus_tag CELE_F49F1.1
        Panther gene CAEEL|WormBase=WBGene00018643|UniProtKB=Q9GZE5
          family PTHR21724
        NCBI gene 177176
        RefSeq protein NM_068084.5
        TREEFAM TREEFAM_ID TF317956
        TrEMBL UniProtAcc Q9GZE5
        UniProt_GCRP UniProtAcc Q9GZE5
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:00 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 29 Apr 2015 12:07:40 WBPerson2970 Name_change: CGC_name: drd-50
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: drd
    Allele (50)
    RNASeq_FPKM (74)
    GO_annotation: 00093042
      00093043
      00093044
    Ortholog (32)
    Paralog (63)
    Structured_description: Automated_description: Involved in defense response to Gram-positive bacterium and innate immune response. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F49F1.1
    Corresponding_transcript: F49F1.1.1
    Other_sequence: NBC01774_1
      NB08687
    Associated_feature: WBsf645906
      WBsf996181
      WBsf228156
      WBsf228157
  Experimental_info: RNAi_result: WBRNAi00078259 Inferred_automatically: RNAi_primary
      WBRNAi00015337 Inferred_automatically: RNAi_primary
      WBRNAi00047876 Inferred_automatically: RNAi_primary
      WBRNAi00032555 Inferred_automatically: RNAi_primary
      WBRNAi00001965 Inferred_automatically: RNAi_primary
      WBRNAi00095432 Inferred_automatically: RNAi_primary
      WBRNAi00095424 Inferred_automatically: RNAi_primary
      WBRNAi00095411 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1022463
      Expr1151705
      Expr2011085
      Expr2029321
    Drives_construct: WBCnstr00026364
    Construct_product: WBCnstr00026364
    Microarray_results (19)
    Expression_cluster: WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:bodywall-muscle_L1-larva_expressed
      WBPaper00037950:CEP-sheath-cells_adult_enriched
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:intestine_larva_enriched
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_RNAseq
      WBPaper00038438:P.lumniescens_24hr_upregulated_TilingArray
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040285:H2S_12hr_upregulated
      WBPaper00042194:nhr-114(RNAi)_downregulated
      WBPaper00042477:rsr-2(RNAi)_upregulated_TilingArray
      WBPaper00042561:smg-2(RNAi)_upregulated
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00042561:smgl-2(RNAi)_downregulated
      WBPaper00044005:DAF-16_downregulated
      WBPaper00044030:nhr-8(hd117)_upregulated
      WBPaper00044557:DietaryRestriction_downregulated
      WBPaper00044736:oscillating_dev_expression
      WBPaper00045303:ZK1236.1(tm4178)_upregulated
      WBPaper00045316:prg-1_upregulated_L4
      WBPaper00045390:tunicamycin_upregulated
      WBPaper00045390:ubc-9(RNAi)_upregulated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045618:fbf-1_downregulated
      WBPaper00045934:wrn-1(gk99)_upregulated
      WBPaper00046337:monosomal_N2_vs_daf-2_upregulated
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_upregulated
      WBPaper00046496:Rifampicin_downregulated
      WBPaper00047131:daf-2(e1370)_downregulated_hel-1(gk148684)-background
      WBPaper00047131:daf-2(e1370)_downregulated_N2-background
      WBPaper00048988:neuron_expressed
      WBPaper00049018:ham-3(RNAi)_downregulated
      WBPaper00049334:CE_intestine_enriched
      WBPaper00049368:daf-2(e1370)_downregulated
      WBPaper00049377:MWCNT_upregulated
      WBPaper00049484:elt-2(RNAi)_downregulated_L4
      WBPaper00049498:npr-1(ur89)_regulated_5
      WBPaper00049635:dop-1(vs100)_upregulated
      WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
      WBPaper00049920:hyl-2(tm2031)_upregulated
      WBPaper00049942:HeatShock_upregulated_hsf-1(+)
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050121:mir-60(n4947)_downregulated
      WBPaper00050163:chd-3(eh4);let-418(RNAi)_downregulated_24-cell-embryo
      WBPaper00050193:cec-4(ok3124)_upregulated_L1
      WBPaper00050234:lin-28(RNAi)_downregulated
      WBPaper00050370:dpy-21(e428)_L3_upregulated
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_adult_25C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050990:body-muscle_enriched
      WBPaper00050990:body-muscle_expressed
      WBPaper00051039:intestine_enriched
      WBPaper00051137:Orsay-virus_upregulated_rde-1(ne219)
      WBPaper00051388:Glucose-diet_downregulated
      WBPaper00053020:sta-1(ok587)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053302:alovudine_24h_regulated
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053302:zidovudine_24h_regulated
      WBPaper00053318:Aging_upregulated_mRNA_N2
      WBPaper00053318:mir-71(n4115)_upregulated_mRNA
      WBPaper00053402:cco-1(RNAi)_upregulated
      WBPaper00053402:his-3(RNAi)_upregulated
      WBPaper00053771:up_at_24h-NaCl
      WBPaper00053771:up_at_dpy-7(e88)
      WBPaper00053810:clk-1(qm30)_upregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:isp-1(qm150)_upregulated
      WBPaper00053810:nuo-6(qm200)_upregulated
      WBPaper00053814:25C_upregulated_OP50
      WBPaper00053814:25C_upregulated_PY79
      WBPaper00053888:drh-3(rrr2)_upregulated
      WBPaper00054493:hpl-2(tm1489)_downregulated
      WBPaper00054872:egl-9(sa307)_upregulated
      WBPaper00055013:hmg-3(bar24)_upregulated
      WBPaper00055013:spt-16(RNAi)_upregulated
      WBPaper00055060:flr-1(RNAi)_downregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Rapamycin-Psora_upregulated
      WBPaper00055354:Rapamycin-Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rapamycin-Rifampicin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin_downregulated
      WBPaper00055386:daf-2(e1370)_downregulated
      WBPaper00055827:daf-2(e1370)_downregulated
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055941:atfs-1(et15)_upregulated
      WBPaper00055941:nuo-6(qm200)_upregulated
      WBPaper00055944:C.butyricum_vs_OP50_downregulated
      WBPaper00055971:nhl-2(ok818)_20C_upregulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056073:NHR-86_interacting_promoter
      WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_upregulated_N2
      WBPaper00056139:gut-microbiota_upregulated
      WBPaper00056167:ifo-1(kc2)_downregulated
      WBPaper00056218:daf-16(mu86)_downregulated_Day7
      WBPaper00056275:P.aeruginosa_upregulated
      WBPaper00056275:P.aeruginosa_upregulated_atf-7(qd22qd130)_dependent
      WBPaper00056275:P.aeruginosa_upregulated_pmk-1(km25)_dependent
      WBPaper00056443:DietaryRestriction_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_upregulated
      WBPaper00056550:ceh-60(ok1485)_upregulated_AdultDay4
      WBPaper00056586:kri-1(ok1251)_upregulated
      WBPaper00056868:P.aeruginosa_upregulated_smallRNA
      WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
      WBPaper00057006:DietaryRestriction_downregulated
      WBPaper00057068:Cadmium_upregulated
      WBPaper00057068:ints-4(RNAi)_upregulated
      WBPaper00057068:ints-4(RNAi)_upregulated_Cadmium
      WBPaper00057196:raga-1(ok386)_upregulated)
      WBPaper00057347:nhr-14(tm1473)_upreglated
      WBPaper00058665:amino-functionized-graphene-oxide_upregulated_mRNA
      WBPaper00058665:graphene-oxide_upregulated_mRNA
      WBPaper00058948:npr-8(ok1439)_downregulated_PA14
      WBPaper00058948:PA14_downregulated
      WBPaper00058955:heatshock_upregulated_CE
      WBPaper00059117:B.subtilis_upregulated
      WBPaper00059191:hsp-16.2p-LIN-29_downregulated
      WBPaper00059253:sucrose_downregulated
      WBPaper00059253:sucrose_stearic-acid_downregulated
      WBPaper00059334:sacy-1(depletion)_regulated
      WBPaper00059421:daf-1(m40);daf-3(mgDf90)_upregulated
      WBPaper00059421:daf-1(m40)_upregulated
      WBPaper00059421:daf-3(mgDf90)_upregulated
      WBPaper00059426:Ag-nanoparticles_upregulated
      WBPaper00059426:SiO2-nanoparticles_downregulated
      WBPaper00059477:lin-32(RNAi)_regulated
      WBPaper00059604:fluvastatin_downregulated_dlk-1(km12)
      WBPaper00059604:fluvastatin_downregulated_N2
      WBPaper00059605:mut-16(pk710)_upregulated
      WBPaper00059735:glucose_downregulated_N2
      WBPaper00059754:P.aeruginosa_PA14_upregulated
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059824:rnp-6(dh1127)_regulated_S.aureus
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00059987:Wounding_upregulated
      WBPaper00060273:isp-1(qm150)_downregulated
      WBPaper00060273:vrk-1(RNAi)_upregulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060764:swsn-1(os22ts)_upregulated
      WBPaper00061081:E.faecalis_upregulated_skpo-1(ok1640)
      WBPaper00061081:skpo-1(ok1640)_upregulated_OG1RF
      WBPaper00061319:pnp-1(jy90)_upregulated
      WBPaper00061319:pnp-1(jy121)_upregulated
      WBPaper00061340:Arcade_cell_anterior_and_posterior
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061390:daf-22(ok693)_ascarosides_downregulated
      WBPaper00061478:pie-1(ne4433)_upregulated
      WBPaper00061527:C17H12.6-swt-6
      WBPaper00061530:nhr-49(e2144)_upregulated
      WBPaper00061590:CGP37157_upregulated
      WBPaper00061636:atracurium_downregulated
      WBPaper00061753:csr-1(tor159)_downregulated_25C
      WBPaper00061952:daf-18(nr2037)_upregulated
      WBPaper00062078:NMR-HspB1_regulated
      WBPaper00062146:MOG-7-degron_2h_regulated
      WBPaper00062156:jmjd-1.2(zr1010)_downregulated
      WBPaper00062156:jmjd-5(zr1234)_updownregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062193:daf-16(RNAi)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062440:crh-1(n3315)_upregulated
      WBPaper00062446:nhr-8(hd117)_upregulated
      WBPaper00062590:Aging_upregulated_intestine
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064107:lin-35(n745)_upregulated
      WBPaper00064130:Beta-Amyloid_24h_upregulated_mRNA
      WBPaper00064382:auxin_upregulated
      WBPaper00064403:Heat-killed-E.Coli_upregulated
      WBPaper00064539:nhr-114(gk849)_upregulated
      WBPaper00064632:daf-2(e1370)_downregulated_intestine
      WBPaper00064721:fasn-1(g14)_downregulated_starved
      WBPaper00064727:daf-2(e1370)_downregulated
      WBPaper00064728:cpl-1(W32AY35A)_upregulated
      WBPaper00064769:him-17(me24)_upregulated
      WBPaper00064871:hypoxia_upregulated_F3
      WBPaper00065005:sams-3(RNAi)_upregulated
      WBPaper00065005:sams-4(RNAi)_upregulated
      WBPaper00065029:cadmium_upregulated
      WBPaper00065086:N2_N.parisii_regulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065158:25C_vs_15C_upregulated_AFD
      WBPaper00065158:25C_vs_15C_upregulated_WholeAnimal
      WBPaper00065749:endu-2(tm4977)_upregulated
      WBPaper00065749:Heat-Shock_downregulated_endu-2(tm4977)
      WBPaper00065823:pmk-1(km25)_downregulated
      WBPaper00065835:Day5_vs_Day1_upregulated
      WBPaper00065835:Day11_vs_Day1_upregulated
      WBPaper00065835:mtH2S-AP39-D0-treatment_upregulated_Day11
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:mml-1(RNAi)-neuron_upregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066204:CdCl2_upregulated_mRNA
      WBPaper00066232:ash-2(RNAi)_downregulated_WT
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      cgc4489_group_11
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:Resveratrol_regulated_daf-16
      WBPaper00028482:PA14_upregulated
      WBPaper00029437:rde-4_upregulated
      WBPaper00031060:2-deoxy-D-glucose_upregulated
      WBPaper00031532:Larva_Pan_Neuronal_Depleted
      WBPaper00032062:age_regulated_genes
      WBPaper00035905:FBF-1_Associated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_D
      WBPaper00037113:Chlorpyrifos_Diazinon_16C_regulated
      WBPaper00037147:heatshock_downregulated
      WBPaper00037704:ABZ_up_regulated
      WBPaper00038462:aging_downregulated
      WBPaper00040210:Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00041002:HQ_3d_2.0mM_Down
      WBPaper00041211:RPW-24_Up
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00042128:gei-8(ok1671)_upregulated
      WBPaper00042274:tbx-2(bx59)_upregulated
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00044091:Bpseudomallei_induced_8h
      WBPaper00044091:Bpseudomallei_induced_12h
      WBPaper00045401:N.parisii_34h_upregulated_N2
      WBPaper00046083:pmk-1(km25)_OP50_downregulated
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_upregulated
      WBPaper00047070:N2_UV_upregulated
      WBPaper00047070:xpa-1_UV_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_upregulated
      WBPaper00057098:SiO2-nanoparticles_downregulated
      [cgc5976]:class_2
    Interaction: WBInteraction000236426
      WBInteraction000292066
      WBInteraction000317892
      WBInteraction000402983
      WBInteraction000455812
      WBInteraction000457799
  Map_info: Map: IV Position: -0.675337
    Positive: Positive_clone: F49F1 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00027722
    WBPaper00028482
    WBPaper00032370
    WBPaper00044557
    WBPaper00058665
    WBPaper00062322
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene