WormBase Tree Display for Gene: WBGene00017571

WBGene00017571 SMap: S_parent: Sequence: F18E9
  Identity: Version: 3
    Name (5)
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:59 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 30 Sep 2011 16:40:15 WBPerson2970 Name_change: CGC_name: jmjd-3.1
        3 08 Aug 2016 09:53:25 WBPerson2970 Name_change: Other_name: tag-279
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: jmjd
    Allele: WBVar02159258
      WBVar01168532
      WBVar01168533
      WBVar01168534
      WBVar01168535
      WBVar01168536
      WBVar01168537
      WBVar01168538
      WBVar01168539
      WBVar01168540
      WBVar01168541
      WBVar01168542
      WBVar01168543
      WBVar01168544
      WBVar01168545
      WBVar02065219
      WBVar01168546
      WBVar01168547
      WBVar01168548
      WBVar01168549
      WBVar01168550
      WBVar00510940
      WBVar00510941
      WBVar00510942
      WBVar00510943
      WBVar00510944
      WBVar00510945
      WBVar00510946
      WBVar00510947
      WBVar00510948
      WBVar00510949
      WBVar00510950
      WBVar00510951
      WBVar00510952
      WBVar00510953
      WBVar00510954
      WBVar00510955
      WBVar01816240
      WBVar01816241
      WBVar01816242
      WBVar00054636
      WBVar01816243
      WBVar00054641
      WBVar01470202
      WBVar01470203
      WBVar00054651
      WBVar00054656
      WBVar00054661
      WBVar01499963
      WBVar01499781
      WBVar01491150
      WBVar01500168
      WBVar01500169
      WBVar01499265
      WBVar01499642
      WBVar01885637
      WBVar01885638
      WBVar01885639
      WBVar00145790
      WBVar02052600
      WBVar00145793
      WBVar01690184
      WBVar01168508
      WBVar01168509
      WBVar01168510
      WBVar01168511
      WBVar01168512
      WBVar01168513
      WBVar01168514
      WBVar01550722
      WBVar01168515
      WBVar01168516
      WBVar01168517
      WBVar01782402
      WBVar01168518
      WBVar01168519
      WBVar01168520
      WBVar01168521
      WBVar01168522
      WBVar01168523
      WBVar01168524
      WBVar01168525
      WBVar02141074
      WBVar01168526
      WBVar01168527
      WBVar02141075
      WBVar01168528
      WBVar02141076
      WBVar01498960
      WBVar01168529
      WBVar02141077
      WBVar01168530
      WBVar01500067
      WBVar01168531
    Strain: WBStrain00036167
      WBStrain00036185
      WBStrain00040876
    RNASeq_FPKM (74)
    GO_annotation (17)
    Ortholog (34)
    Paralog: WBGene00007813 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00009089 Caenorhabditis elegans From_analysis: TreeFam
            Inparanoid_8
            Panther
            WormBase-Compara
      WBGene00017046 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: jmjd-3.1 encodes, by alternative splicing, two isoforms of a histone H3 trimethyllysine-27 (H3K27me3) demethylase that is required for normal gonad migration and organization; JMJD-3.1 demethylates H3K27me3 in vitro; JMJD-3.1 contains an N-terminal TonB domain and a C-terminal JmjC domain, and is homologous to human JMJD3, UTX (OMIM:300128), and UTY (OMIM:400009); null jmjd-3.1(gk384) and jmjd-3.1(gk387) mutants have aberrant gonad migration and disordered diakinesis-phase oocytes, phenotypes enhanced at 25 deg. C.; JMJD-3.1 is expected to antagonize transcriptional repression by polycomb repressor complexes, which mark stem cells (and presumably germline) by H3K27me3-mediated repression of somatic genes. Paper_evidence: WBPaper00030964
          Curator_confirmed: WBPerson1843
            WBPerson567
          Date_last_updated: 03 Aug 2011 00:00:00
      Automated_description: Enables histone H3K27me2/H3K27me3 demethylase activity. Involved in transdifferentiation. Located in nucleus. Expressed in PDA and Y cell. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F18E9.5a
      F18E9.5b
    Corresponding_transcript: F18E9.5a.1
      F18E9.5a.2
      F18E9.5a.3
      F18E9.5b.1
    Associated_feature: WBsf655200
      WBsf663046
      WBsf716866
      WBsf716867
      WBsf717349
      WBsf1006198
      WBsf1006199
      WBsf1023440
      WBsf236063
      WBsf236064
  Experimental_info: RNAi_result: WBRNAi00103685 Inferred_automatically: RNAi_primary
      WBRNAi00066130 Inferred_automatically: RNAi_primary
      WBRNAi00044959 Inferred_automatically: RNAi_primary
      WBRNAi00089510 Inferred_automatically: RNAi_primary
      WBRNAi00091497 Inferred_automatically: RNAi_primary
      WBRNAi00001913 Inferred_automatically: RNAi_primary
      WBRNAi00013518 Inferred_automatically: RNAi_primary
      WBRNAi00089509 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr11956
      Expr1012855
      Expr1037547
      Expr1148928
      Expr2012888
      Expr2031122
    Drives_construct: WBCnstr00019767
      WBCnstr00020760
      WBCnstr00020762
      WBCnstr00037997
    Construct_product: WBCnstr00019767
      WBCnstr00020760
      WBCnstr00020762
      WBCnstr00037997
    Regulate_expr_cluster: WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
    Microarray_results (26)
    Expression_cluster (184)
    Interaction (21)
  Map_info: Map: X Position: 0.120563 Error: 0.008795
    Positive: Positive_clone: F18E9 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5117
        5495
        5569
    Pseudo_map_position
  Reference (16)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene