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WormBase Tree Display for Gene: WBGene00009089

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Name Class

WBGene00009089SMapS_parentSequenceF23D12
IdentityVersion2
NameCGC_namejmjd-3.2Person_evidenceWBPerson1422
Sequence_nameF23D12.5
Molecular_nameF23D12.5
F23D12.5.1
CE15893
Other_nameCELE_F23D12.5Accession_evidenceNDBBX284606
Public_namejmjd-3.2
DB_infoDatabaseAceViewgeneXP71
WormQTLgeneWBGene00009089
WormFluxgeneWBGene00009089
NDBlocus_tagCELE_F23D12.5
PanthergeneCAEEL|WormBase=WBGene00009089|UniProtKB=Q19760
familyPTHR14017
NCBIgene181543
RefSeqproteinNM_078004.6
TREEFAMTREEFAM_IDTF317405
TrEMBLUniProtAccQ19760
UniProt_GCRPUniProtAccQ19760
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:49WBPerson1971EventImportedInitial conversion from CDS class of WS125
230 Sep 2011 16:40:15WBPerson2970Name_changeCGC_namejmjd-3.2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classjmjd
Allele (118)
RNASeq_FPKM (74)
GO_annotation00065772
00065773
00065774
00065775
00065776
00065777
00065778
00065779
Ortholog (29)
ParalogWBGene00007813Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
WormBase-Compara
WBGene00017046Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
WBGene00017571Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionF23D12.5 encodes a putative histone H3 di/trimethyllysine-27 (H3K27me2/me3) demethylase; F23D12.5 contains a C-terminal JmjC domain, and is homologous to human JMJD3, UTX (OMIM:300128), and UTY (OMIM:400009); F23D12.5 is expected to antagonize transcriptional repression by polycomb repressor complexes, which mark stem cells (and presumably germline) by H3K27me3-mediated repression of somatic genes; however, F23D12.5 has no obvious function in mass RNAi assays.Paper_evidenceWBPaper00030964
Curator_confirmedWBPerson567
Date_last_updated01 Oct 2007 00:00:00
Automated_descriptionPredicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; chromatin DNA binding activity; and histone H3K27me2/H3K27me3 demethylase activity. Predicted to be involved in regulation of gene expression. Predicted to be located in nucleus. Predicted to be part of MLL3/4 complex.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF23D12.5
Corresponding_transcriptF23D12.5.1
Other_sequenceCRC12491_1
CRC05706_1
CR04641
CR05874
CRC07734_1
CR04240
Associated_featureWBsf1007909
WBsf236674
Experimental_infoRNAi_resultWBRNAi00103686Inferred_automaticallyRNAi_primary
WBRNAi00031321Inferred_automaticallyRNAi_primary
WBRNAi00013815Inferred_automaticallyRNAi_primary
WBRNAi00091503Inferred_automaticallyRNAi_primary
WBRNAi00045412Inferred_automaticallyRNAi_primary
Expr_patternExpr1024582
Expr1033960
Expr1149336
Expr2012889
Expr2031123
Drives_constructWBCnstr00032473
Construct_productWBCnstr00032473
Microarray_results (18)
Expression_cluster (166)
Interaction (241)
Map_infoMapXPosition16.7056
PositivePositive_cloneF23D12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00030964
WBPaper00038372
WBPaper00038491
WBPaper00039978
WBPaper00047514
WBPaper00055090
WBPaper00061216
WBPaper00065308
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene