WormBase Tree Display for Gene: WBGene00017571
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| WBGene00017571 | SMap | S_parent | Sequence | F18E9 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | jmjd-3.1 | Person_evidence | WBPerson1422 | |||||
| Sequence_name | F18E9.5 | ||||||||
| Molecular_name | F18E9.5a | ||||||||
| F18E9.5a.1 | |||||||||
| CE30957 | |||||||||
| F18E9.5b | |||||||||
| CE30958 | |||||||||
| F18E9.5a.2 | |||||||||
| F18E9.5a.3 | |||||||||
| F18E9.5b.1 | |||||||||
| Other_name | tag-279 | ||||||||
| CELE_F18E9.5 | Accession_evidence | NDB | BX284606 | ||||||
| Public_name | jmjd-3.1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:59 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 30 Sep 2011 16:40:15 | WBPerson2970 | Name_change | CGC_name | jmjd-3.1 | ||||
| 3 | 08 Aug 2016 09:53:25 | WBPerson2970 | Name_change | Other_name | tag-279 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | jmjd | ||||||||
| Allele (94) | |||||||||
| Strain | WBStrain00036167 | ||||||||
| WBStrain00036185 | |||||||||
| WBStrain00040876 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (17) | |||||||||
| Ortholog (34) | |||||||||
| Paralog | WBGene00007813 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
| Inparanoid_8 | |||||||||
| WormBase-Compara | |||||||||
| WBGene00009089 | Caenorhabditis elegans | From_analysis | TreeFam | ||||||
| Inparanoid_8 | |||||||||
| Panther | |||||||||
| WormBase-Compara | |||||||||
| WBGene00017046 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | jmjd-3.1 encodes, by alternative splicing, two isoforms of a histone H3 trimethyllysine-27 (H3K27me3) demethylase that is required for normal gonad migration and organization; JMJD-3.1 demethylates H3K27me3 in vitro; JMJD-3.1 contains an N-terminal TonB domain and a C-terminal JmjC domain, and is homologous to human JMJD3, UTX (OMIM:300128), and UTY (OMIM:400009); null jmjd-3.1(gk384) and jmjd-3.1(gk387) mutants have aberrant gonad migration and disordered diakinesis-phase oocytes, phenotypes enhanced at 25 deg. C.; JMJD-3.1 is expected to antagonize transcriptional repression by polycomb repressor complexes, which mark stem cells (and presumably germline) by H3K27me3-mediated repression of somatic genes. | Paper_evidence | WBPaper00030964 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 03 Aug 2011 00:00:00 | ||||||||
| Automated_description | Enables histone H3K27me2/H3K27me3 demethylase activity. Involved in transdifferentiation. Located in nucleus. Expressed in PDA and Y cell. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F18E9.5a | |||||||
| F18E9.5b | |||||||||
| Corresponding_transcript | F18E9.5a.1 | ||||||||
| F18E9.5a.2 | |||||||||
| F18E9.5a.3 | |||||||||
| F18E9.5b.1 | |||||||||
| Associated_feature | WBsf655200 | ||||||||
| WBsf663046 | |||||||||
| WBsf716866 | |||||||||
| WBsf716867 | |||||||||
| WBsf717349 | |||||||||
| WBsf1006198 | |||||||||
| WBsf1006199 | |||||||||
| WBsf1023440 | |||||||||
| WBsf236063 | |||||||||
| WBsf236064 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00103685 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00066130 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00044959 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00089510 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00091497 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00001913 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00013518 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00089509 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr11956 | ||||||||
| Expr1012855 | |||||||||
| Expr1037547 | |||||||||
| Expr1148928 | |||||||||
| Expr2012888 | |||||||||
| Expr2031122 | |||||||||
| Drives_construct | WBCnstr00019767 | ||||||||
| WBCnstr00020760 | |||||||||
| WBCnstr00020762 | |||||||||
| WBCnstr00037997 | |||||||||
| Construct_product | WBCnstr00019767 | ||||||||
| WBCnstr00020760 | |||||||||
| WBCnstr00020762 | |||||||||
| WBCnstr00037997 | |||||||||
| Regulate_expr_cluster | WBPaper00049545:jmjd-3.1(+)_downregulated | ||||||||
| WBPaper00049545:jmjd-3.1(+)_upregulated | |||||||||
| Microarray_results (26) | |||||||||
| Expression_cluster (184) | |||||||||
| Interaction (21) | |||||||||
| Map_info | Map | X | Position | 0.120563 | Error | 0.008795 | |||
| Positive | Positive_clone | F18E9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5117 | |||||||
| 5495 | |||||||||
| 5569 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (16) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
