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WormBase Tree Display for Gene: WBGene00009089

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Name Class

WBGene00009089SMapS_parentSequenceF23D12
IdentityVersion2
NameCGC_namejmjd-3.2Person_evidenceWBPerson1422
Sequence_nameF23D12.5
Molecular_nameF23D12.5
F23D12.5.1
CE15893
Other_nameCELE_F23D12.5Accession_evidenceNDBBX284606
Public_namejmjd-3.2
DB_infoDatabaseAceViewgeneXP71
WormQTLgeneWBGene00009089
WormFluxgeneWBGene00009089
NDBlocus_tagCELE_F23D12.5
PanthergeneCAEEL|WormBase=WBGene00009089|UniProtKB=Q19760
familyPTHR14017
NCBIgene181543
RefSeqproteinNM_078004.6
TREEFAMTREEFAM_IDTF317405
TrEMBLUniProtAccQ19760
UniProt_GCRPUniProtAccQ19760
SpeciesCaenorhabditis elegans
HistoryVersion_change126 May 2004 16:54:49WBPerson1971EventImportedInitial conversion from CDS class of WS125
230 Sep 2011 16:40:15WBPerson2970Name_changeCGC_namejmjd-3.2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classjmjd
Allele (118)
RNASeq_FPKM (74)
GO_annotation00065772
00065773
00065774
00065775
00065776
00065777
00065778
00065779
Ortholog (29)
ParalogWBGene00007813Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
WormBase-Compara
WBGene00017046Caenorhabditis elegansFrom_analysisTreeFam
WormBase-Compara
WBGene00017571Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionF23D12.5 encodes a putative histone H3 di/trimethyllysine-27 (H3K27me2/me3) demethylase; F23D12.5 contains a C-terminal JmjC domain, and is homologous to human JMJD3, UTX (OMIM:300128), and UTY (OMIM:400009); F23D12.5 is expected to antagonize transcriptional repression by polycomb repressor complexes, which mark stem cells (and presumably germline) by H3K27me3-mediated repression of somatic genes; however, F23D12.5 has no obvious function in mass RNAi assays.Paper_evidenceWBPaper00030964
Curator_confirmedWBPerson567
Date_last_updated01 Oct 2007 00:00:00
Automated_descriptionPredicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; chromatin DNA binding activity; and histone H3K27me2/H3K27me3 demethylase activity. Predicted to be involved in regulation of gene expression. Predicted to be located in nucleus. Predicted to be part of MLL3/4 complex.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF23D12.5
Corresponding_transcriptF23D12.5.1
Other_sequenceCRC12491_1
CRC05706_1
CR04641
CR05874
CRC07734_1
CR04240
Associated_featureWBsf1007909
WBsf236674
Experimental_infoRNAi_resultWBRNAi00103686Inferred_automaticallyRNAi_primary
WBRNAi00031321Inferred_automaticallyRNAi_primary
WBRNAi00013815Inferred_automaticallyRNAi_primary
WBRNAi00091503Inferred_automaticallyRNAi_primary
WBRNAi00045412Inferred_automaticallyRNAi_primary
Expr_patternExpr1024582
Expr1033960
Expr1149336
Expr2012889
Expr2031123
Drives_constructWBCnstr00032473
Construct_productWBCnstr00032473
Microarray_results (18)
Expression_cluster (166)
Interaction (241)
Map_infoMapXPosition16.7056
PositivePositive_cloneF23D12Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (8)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene