WormBase Tree Display for Gene: WBGene00017571
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WBGene00017571 | SMap | S_parent | Sequence | F18E9 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | jmjd | ||||||
Allele (94) | |||||||
Strain | WBStrain00036167 | ||||||
WBStrain00036185 | |||||||
WBStrain00040876 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (17) | |||||||
Ortholog (34) | |||||||
Paralog | WBGene00007813 | Caenorhabditis elegans | From_analysis | TreeFam | |||
Inparanoid_8 | |||||||
WormBase-Compara | |||||||
WBGene00009089 | Caenorhabditis elegans | From_analysis | TreeFam | ||||
Inparanoid_8 | |||||||
Panther | |||||||
WormBase-Compara | |||||||
WBGene00017046 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
Structured_description | Concise_description | jmjd-3.1 encodes, by alternative splicing, two isoforms of a histone H3 trimethyllysine-27 (H3K27me3) demethylase that is required for normal gonad migration and organization; JMJD-3.1 demethylates H3K27me3 in vitro; JMJD-3.1 contains an N-terminal TonB domain and a C-terminal JmjC domain, and is homologous to human JMJD3, UTX (OMIM:300128), and UTY (OMIM:400009); null jmjd-3.1(gk384) and jmjd-3.1(gk387) mutants have aberrant gonad migration and disordered diakinesis-phase oocytes, phenotypes enhanced at 25 deg. C.; JMJD-3.1 is expected to antagonize transcriptional repression by polycomb repressor complexes, which mark stem cells (and presumably germline) by H3K27me3-mediated repression of somatic genes. | Paper_evidence | WBPaper00030964 | |||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson567 | |||||||
Date_last_updated | 03 Aug 2011 00:00:00 | ||||||
Automated_description | Enables histone H3K27me2/H3K27me3 demethylase activity. Involved in transdifferentiation. Located in nucleus. Expressed in PDA and Y cell. | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | F18E9.5a | |||||
F18E9.5b | |||||||
Corresponding_transcript | F18E9.5a.1 | ||||||
F18E9.5a.2 | |||||||
F18E9.5a.3 | |||||||
F18E9.5b.1 | |||||||
Associated_feature | WBsf655200 | ||||||
WBsf663046 | |||||||
WBsf716866 | |||||||
WBsf716867 | |||||||
WBsf717349 | |||||||
WBsf1006198 | |||||||
WBsf1006199 | |||||||
WBsf1023440 | |||||||
WBsf236063 | |||||||
WBsf236064 | |||||||
Experimental_info | RNAi_result | WBRNAi00103685 | Inferred_automatically | RNAi_primary | |||
WBRNAi00066130 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00044959 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00089510 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00091497 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00001913 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00013518 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00089509 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Expr11956 | ||||||
Expr1012855 | |||||||
Expr1037547 | |||||||
Expr1148928 | |||||||
Expr2012888 | |||||||
Expr2031122 | |||||||
Drives_construct | WBCnstr00019767 | ||||||
WBCnstr00020760 | |||||||
WBCnstr00020762 | |||||||
WBCnstr00037997 | |||||||
Construct_product | WBCnstr00019767 | ||||||
WBCnstr00020760 | |||||||
WBCnstr00020762 | |||||||
WBCnstr00037997 | |||||||
Regulate_expr_cluster | WBPaper00049545:jmjd-3.1(+)_downregulated | ||||||
WBPaper00049545:jmjd-3.1(+)_upregulated | |||||||
Microarray_results (26) | |||||||
Expression_cluster (184) | |||||||
Interaction (21) | |||||||
Map_info | Map | X | Position | 0.120563 | Error | 0.008795 | |
Positive | Positive_clone | F18E9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Mapping_data | Multi_point | 5117 | |||||
5495 | |||||||
5569 | |||||||
Pseudo_map_position | |||||||
Reference (16) | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |