WormBase Tree Display for Gene: WBGene00017440

WBGene00017440 SMap: S_parent: Sequence: F13H8
  Identity: Version: 2
    Name: CGC_name: upb-1 Paper_evidence: WBPaper00037116
      Sequence_name: F13H8.7
      Molecular_name: F13H8.7
        F13H8.7.1
        CE02641
      Other_name: CELE_F13H8.7 Accession_evidence: NDB BX284602
      Public_name: upb-1
    DB_info: Database: AceView gene 2G578
        WormQTL gene WBGene00017440
        WormFlux gene WBGene00017440
        NDB locus_tag CELE_F13H8.7
        Panther gene CAEEL|WormBase=WBGene00017440|UniProtKB=Q19437
          family PTHR43674
        NCBI gene 174040
        RefSeq protein NM_062860.5
        TREEFAM TREEFAM_ID TF313402
        TrEMBL UniProtAcc Q19437
        UniProt_GCRP UniProtAcc Q19437
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:58 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 14 Sep 2010 16:06:52 WBPerson2970 Name_change: CGC_name: upb-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: upb
    Allele (23)
    RNASeq_FPKM (74)
    GO_annotation (11)
    Ortholog (42)
    Paralog: WBGene00003594 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00014206 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Concise_description: upb-1 encodes the C. elegans ortholog of 3-ureidopropionase; UPB-1 exhibits enzymatic activity in vitro, catalyzing the catabolism of 3-ureidopropionate and 2-methyl-3-ureidopropionate; a UPB-1::GFP fusion is expressed throughout larval development and in adults; UPB-1::GFP localizes to the dense body of striated body wall muscles, suggesting that UPB-1 may play a role in synthesis of carnosin-like dipeptides. Paper_evidence: WBPaper00037116
          Curator_confirmed: WBPerson1843
          Date_last_updated: 19 Jan 2011 00:00:00
      Automated_description: Enables beta-ureidopropionase activity. Involved in beta-alanine biosynthetic process via 3-ureidopropionate; thymine catabolic process; and uracil catabolic process. Located in striated muscle dense body. Expressed in body wall musculature. Is an ortholog of human UPB1 (beta-ureidopropionase 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: F13H8.7
    Corresponding_transcript: F13H8.7.1
    Other_sequence (107)
    Associated_feature: WBsf650126
      WBsf223145
  Experimental_info: RNAi_result: WBRNAi00044563 Inferred_automatically: RNAi_primary
      WBRNAi00110189 Inferred_automatically: RNAi_primary
      WBRNAi00110190 Inferred_automatically: RNAi_primary
      WBRNAi00013253 Inferred_automatically: RNAi_primary
      WBRNAi00033373 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr9128
      Expr13615
      Expr1020371
      Expr1037503
      Expr1148520
      Expr2017927
      Expr2036063
    Drives_construct: WBCnstr00013735
      WBCnstr00027298
      WBCnstr00039724
    Construct_product: WBCnstr00013735
      WBCnstr00027298
      WBCnstr00039724
    Microarray_results (21)
    Expression_cluster (189)
    Interaction (35)
  Map_info: Map: II Position: -0.389204 Error: 0.000694
    Positive: Positive_clone: F13H8 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00037116
    WBPaper00038491
    WBPaper00041771
    WBPaper00055090
    WBPaper00065140
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene