WormBase Tree Display for Gene: WBGene00017132

WBGene00017132 SMap: S_parent: Sequence: F07F6
  Identity: Version: 7
    Name: CGC_name: tofu-6
      Sequence_name: EEED8.1
      Molecular_name: EEED8.1
        EEED8.1.1
        CE26746
      Other_name: mel-2 Person_evidence: WBPerson314
        mel-47 Person_evidence: WBPerson629
            WBPerson314
        CELE_EEED8.1 Accession_evidence: NDB BX284602
      Public_name: tofu-6
    DB_info: Database: AceView gene 2F713
        WormQTL gene WBGene00017132
        NDB locus_tag CELE_EEED8.1
        NCBI gene 24104386
        RefSeq protein NM_001306578.5
        SwissProt UniProtAcc Q09293
        UniProt_GCRP UniProtAcc Q09293
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:58 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 01 Apr 2005 11:05:24 WBPerson2970 Name_change: CGC_name: tudr-1
        3 16 Oct 2006 16:56:31 WBPerson2970 Name_change: CGC_name: mel-47
                Other_name: tudr-1
        4 28 Mar 2014 15:50:22 WBPerson2970 Name_change: CGC_name: tofu-6
                Other_name: mel-47
        5 02 Sep 2014 12:40:48 WBPerson2970 Name_change: CGC_name: mel-47
                Other_name: tofu-6
        6 25 Mar 2015 15:33:40 WBPerson2970 Event: Acquires_merge: WBGene00003188
              Name_change: CGC_name: tofu-6
                Other_name: mel-2
        7 25 Mar 2015 15:34:24 WBPerson2970 Name_change: Other_name: mel-47
      Acquires_merge: WBGene00003188
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: tofu
    Reference_allele: WBVar00275444
      WBVar00088001
    Allele (31)
    Legacy_information: [C.elegansII] it20 : strict maternal effect embryonic lethal. OA1: it22. [Kemphues et al. 1988]
    Strain: WBStrain00023566
      WBStrain00031149
    RNASeq_FPKM (74)
    GO_annotation (33)
    Ortholog (23)
    Structured_description: Automated_description: Predicted to enable RNA binding activity. Involved in several processes, including embryonic cleavage; mitotic sister chromatid separation; and nucleic acid metabolic process. Located in nucleus and perinuclear region of cytoplasm. Expressed in germ line. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: EEED8.1
    Corresponding_transcript: EEED8.1.1
    Other_sequence: CRC09352_1
      CJC06104_1
      CR00454
      CBC05784_1
    Associated_feature: WBsf644193
      WBsf644194
      WBsf221278
  Experimental_info: RNAi_result: WBRNAi00113939 Inferred_automatically: RNAi_primary
      WBRNAi00043689 Inferred_automatically: RNAi_primary
      WBRNAi00022694 Inferred_automatically: RNAi_primary
      WBRNAi00103067 Inferred_automatically: RNAi_primary
      WBRNAi00033559 Inferred_automatically: RNAi_primary
      WBRNAi00008592 Inferred_automatically: RNAi_primary
      WBRNAi00113938 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr8287
      Expr14432
      Expr16061
      Expr1026068
      Expr1037359
      Expr1147673
      Expr2017448
      Expr2035587
    Drives_construct: WBCnstr00016926
      WBCnstr00037834
      WBCnstr00040803
      WBCnstr00042743
    Construct_product: WBCnstr00016926
      WBCnstr00037834
      WBCnstr00040803
      WBCnstr00042743
    Regulate_expr_cluster: WBPaper00056900:TOFU-6_interacting
    Microarray_results (20)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00037682:sma-2_sma-4_downregulated
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00038289:oocyte_protein
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00040412:germline-regulated_daf-12_target
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044760:germline_specific
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
      WBPaper00045050:csr-1(hypomorph)_downregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00046509:lin-35(n745)_upregulated
      WBPaper00046795:starvation_downregulated
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050015:ifg-1(RNAi)_downregulated
      WBPaper00050193:cec-4(ok3124)_downregulated_L1
      WBPaper00050193:met-2(n4256)set-25(n5021)_downregulated_L1
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050686:glp-1(e2141)_downregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:NMDA-neuron_enriched
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051461:pig-1(gm344)_upregulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_downregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053814:25C_downregulated_OP50
      WBPaper00053814:25C_downregulated_PY79
      WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056275:P.aeruginosa_downregulated_atf-7(qd22qd130)_dependent
      WBPaper00056275:P.aeruginosa_downregulated_pmk-1(km25)_dependent
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056826:hmc_biased
      WBPaper00056900:ERH-2_interacting
      WBPaper00056900:PID-3_interacting
      WBPaper00056900:TOFU-6_interacting
      WBPaper00056900:TOST-1_interacting
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057154:HeatShock_downregulated_mRNA
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058598:mex-3(eu149)_downregulated
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059566:wdr-23(mac32)_downregulated
      WBPaper00059609:malt-1_ilc-17.1_nfki-1_downregulated
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00061007:HB101_downregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061203:spr-1(ok2144)_downregulated
      WBPaper00061274:hypergravity_10xg_upregulated
      WBPaper00061274:hypergravity_15xg_upregulated
      WBPaper00061340:Ciliated_amphid_neuron
      WBPaper00061340:Ciliated_non_amphid_neuron
      WBPaper00061340:I2_grandparent
      WBPaper00061340:Neuroblast_ASE_ASJ_AUA
      WBPaper00061340:Neuroblast_IL1_IL2
      WBPaper00061340:OLQ_grandparent
      WBPaper00061340:PLM_ALN_great_grandparent
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061466:nath-10(icb102)_upregulated
      WBPaper00061699:daf-18(ok480)_upregulated
      WBPaper00061818:ELKS-1_interacting
      WBPaper00062056:efl-1(se1)_upregulated
      WBPaper00062056:lin-35(n745)_upregulated
      WBPaper00062056:lin-36(we31)_upregulated
      WBPaper00062056:lin-36(we36)_upregulated
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062293:isp-1(qm150)_downregulated
      WBPaper00062325:etr-1(lq61)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062456:doxycycline_downregulated_CB4856_protein
      WBPaper00062456:doxycycline_downregulated_N2_protein
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00064071:NHR-49_interacting
      WBPaper00064080:let-7_miRNA_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00065841:3_0
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_2
      WBPaper00025032:cluster_40
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00035227:heat_shock_regulated
      WBPaper00035479:daf-16(RNAi)_upregulated
      WBPaper00036123:Fluoranthene_regulated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_B
      WBPaper00039866:ClassComp_daf-19_upregulated
      WBPaper00040426:CYD-1_CDK-4_upregulated
      WBPaper00040426:CYE-1_CDK-2AF_upregulated
      WBPaper00040963:TA300_down
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041906:I-3690_vs_OP50_3d
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053550:daf-19(m86)_upregulated_3-fold-embryo
      WBPaper00056330:mrps-5(RNAi)_downregulated
      [cgc5767]:cluster_3
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(186_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_ME
      [cgc6390]:Cluster_E
      [cgc6390]:oogenesis-enriched
    Interaction: WBInteraction000160423
      WBInteraction000180024
      WBInteraction000181774
      WBInteraction000184088
      WBInteraction000186183
      WBInteraction000187059
      WBInteraction000187898
      WBInteraction000190909
      WBInteraction000193129
      WBInteraction000194373
      WBInteraction000205077
      WBInteraction000205455
      WBInteraction000205532
      WBInteraction000206209
      WBInteraction000207534
      WBInteraction000209826
      WBInteraction000210611
      WBInteraction000210982
      WBInteraction000215316
      WBInteraction000218626
      WBInteraction000220983
      WBInteraction000222996
      WBInteraction000223973
      WBInteraction000224232
      WBInteraction000228939
      WBInteraction000229939
      WBInteraction000230280
      WBInteraction000230798
      WBInteraction000232743
      WBInteraction000233547
      WBInteraction000234849
      WBInteraction000237272
      WBInteraction000239356
      WBInteraction000243178
      WBInteraction000248554
      WBInteraction000249489
      WBInteraction000251874
      WBInteraction000252194
      WBInteraction000253899
      WBInteraction000254816
      WBInteraction000256912
      WBInteraction000258167
      WBInteraction000261770
      WBInteraction000261989
      WBInteraction000263613
      WBInteraction000264188
      WBInteraction000267322
      WBInteraction000268315
      WBInteraction000269190
      WBInteraction000269329
      WBInteraction000270336
      WBInteraction000270923
      WBInteraction000276325
      WBInteraction000276665
      WBInteraction000276835
      WBInteraction000277479
      WBInteraction000278996
      WBInteraction000283957
      WBInteraction000285597
      WBInteraction000287682
      WBInteraction000292198
      WBInteraction000294488
      WBInteraction000297875
      WBInteraction000300763
      WBInteraction000304384
      WBInteraction000304576
      WBInteraction000308691
      WBInteraction000308797
      WBInteraction000310896
      WBInteraction000313125
      WBInteraction000318661
      WBInteraction000321529
      WBInteraction000325260
      WBInteraction000325912
      WBInteraction000326903
      WBInteraction000332061
      WBInteraction000334533
      WBInteraction000336268
      WBInteraction000338274
      WBInteraction000338674
      WBInteraction000338727
      WBInteraction000338915
      WBInteraction000339099
      WBInteraction000339284
      WBInteraction000340448
      WBInteraction000342481
      WBInteraction000343902
      WBInteraction000345269
      WBInteraction000346994
      WBInteraction000347152
      WBInteraction000347480
      WBInteraction000348266
      WBInteraction000349759
      WBInteraction000350516
      WBInteraction000350876
      WBInteraction000350929
      WBInteraction000354281
      WBInteraction000357573
      WBInteraction000357705
      WBInteraction000357920
      WBInteraction000358703
      WBInteraction000360386
      WBInteraction000361509
      WBInteraction000361868
      WBInteraction000361900
      WBInteraction000362413
      WBInteraction000362504
      WBInteraction000362605
      WBInteraction000362802
      WBInteraction000363623
      WBInteraction000364630
      WBInteraction000366109
      WBInteraction000368912
      WBInteraction000371301
      WBInteraction000372027
      WBInteraction000372192
      WBInteraction000373516
      WBInteraction000373738
      WBInteraction000373851
      WBInteraction000380432
      WBInteraction000381054
      WBInteraction000383179
      WBInteraction000383772
      WBInteraction000387580
      WBInteraction000391083
      WBInteraction000391269
      WBInteraction000393366
      WBInteraction000397086
      WBInteraction000398658
      WBInteraction000398874
      WBInteraction000400688
      WBInteraction000401468
      WBInteraction000402469
      WBInteraction000411050
      WBInteraction000412078
      WBInteraction000412300
      WBInteraction000414259
      WBInteraction000416714
      WBInteraction000418323
      WBInteraction000419391
      WBInteraction000420223
      WBInteraction000422474
      WBInteraction000424780
      WBInteraction000425170
      WBInteraction000425924
      WBInteraction000428182
      WBInteraction000428360
      WBInteraction000428401
      WBInteraction000430405
      WBInteraction000430854
      WBInteraction000432517
      WBInteraction000437887
      WBInteraction000437903
      WBInteraction000438056
      WBInteraction000438252
      WBInteraction000438303
      WBInteraction000439850
      WBInteraction000439899
      WBInteraction000440141
      WBInteraction000440355
      WBInteraction000440366
      WBInteraction000443838
      WBInteraction000448839
      WBInteraction000450184
      WBInteraction000452421
      WBInteraction000453483
      WBInteraction000456683
      WBInteraction000457817
      WBInteraction000458396
      WBInteraction000458631
      WBInteraction000461173
      WBInteraction000461291
      WBInteraction000461980
      WBInteraction000462446
      WBInteraction000462500
      WBInteraction000502737
      WBInteraction000523112
      WBInteraction000525290
      WBInteraction000547260
      WBInteraction000547660
      WBInteraction000547661
      WBInteraction000549063
      WBInteraction000560067
      WBInteraction000561014
      WBInteraction000561019
      WBInteraction000561020
      WBInteraction000561025
      WBInteraction000561040
      WBInteraction000561049
      WBInteraction000561058
      WBInteraction000561059
      WBInteraction000561060
      WBInteraction000561061
      WBInteraction000561062
      WBInteraction000561063
      WBInteraction000561064
      WBInteraction000561065
      WBInteraction000561066
      WBInteraction000561077
      WBInteraction000561589
      WBInteraction000561590
      WBInteraction000561594
      WBInteraction000561663
      WBInteraction000561664
      WBInteraction000561665
      WBInteraction000561666
      WBInteraction000561667
      WBInteraction000561668
      WBInteraction000561669
      WBInteraction000561670
      WBInteraction000561671
      WBInteraction000561672
      WBInteraction000561673
      WBInteraction000561674
      WBInteraction000561675
      WBInteraction000561676
      WBInteraction000561677
      WBInteraction000561678
      WBInteraction000561679
      WBInteraction000561680
      WBInteraction000561681
      WBInteraction000561682
      WBInteraction000561683
      WBInteraction000561684
      WBInteraction000561685
      WBInteraction000561686
      WBInteraction000561687
      WBInteraction000561688
      WBInteraction000561689
      WBInteraction000561690
      WBInteraction000561691
      WBInteraction000561692
      WBInteraction000561693
      WBInteraction000561694
      WBInteraction000561695
      WBInteraction000561696
      WBInteraction000561697
      WBInteraction000561698
      WBInteraction000561699
      WBInteraction000561700
      WBInteraction000561701
      WBInteraction000561702
      WBInteraction000561703
      WBInteraction000561704
      WBInteraction000561705
      WBInteraction000561706
      WBInteraction000561707
      WBInteraction000561708
      WBInteraction000561709
      WBInteraction000561710
      WBInteraction000561711
      WBInteraction000561712
      WBInteraction000561713
      WBInteraction000561714
      WBInteraction000561715
      WBInteraction000561716
      WBInteraction000561717
      WBInteraction000561718
      WBInteraction000561719
      WBInteraction000561720
      WBInteraction000561721
      WBInteraction000561722
      WBInteraction000561723
      WBInteraction000561724
      WBInteraction000561725
      WBInteraction000561726
      WBInteraction000561727
      WBInteraction000561728
      WBInteraction000561729
      WBInteraction000561730
      WBInteraction000561731
      WBInteraction000561732
      WBInteraction000561733
      WBInteraction000561734
      WBInteraction000561735
      WBInteraction000561736
      WBInteraction000561737
      WBInteraction000561738
      WBInteraction000561739
      WBInteraction000561740
      WBInteraction000561741
      WBInteraction000561742
      WBInteraction000561743
      WBInteraction000561744
      WBInteraction000561745
      WBInteraction000561746
      WBInteraction000561747
      WBInteraction000561748
      WBInteraction000561749
      WBInteraction000561750
      WBInteraction000561751
      WBInteraction000561752
      WBInteraction000561753
      WBInteraction000561754
      WBInteraction000561755
      WBInteraction000561756
      WBInteraction000561757
      WBInteraction000561758
      WBInteraction000561759
      WBInteraction000561760
      WBInteraction000561761
      WBInteraction000561762
      WBInteraction000561763
      WBInteraction000561764
      WBInteraction000561765
      WBInteraction000561766
      WBInteraction000561767
      WBInteraction000561768
      WBInteraction000561769
      WBInteraction000561770
      WBInteraction000561771
      WBInteraction000561772
      WBInteraction000561773
      WBInteraction000561774
      WBInteraction000561775
      WBInteraction000561776
      WBInteraction000561777
      WBInteraction000561778
      WBInteraction000561779
      WBInteraction000561780
      WBInteraction000561781
      WBInteraction000561782
      WBInteraction000561783
      WBInteraction000561784
      WBInteraction000561785
      WBInteraction000561786
      WBInteraction000561787
      WBInteraction000561788
      WBInteraction000561789
      WBInteraction000561790
      WBInteraction000561791
      WBInteraction000561792
      WBInteraction000561793
      WBInteraction000561794
      WBInteraction000561795
      WBInteraction000561796
      WBInteraction000561797
      WBInteraction000561798
      WBInteraction000561799
      WBInteraction000561800
      WBInteraction000561801
      WBInteraction000561802
      WBInteraction000561803
      WBInteraction000561804
      WBInteraction000561805
      WBInteraction000561806
      WBInteraction000561807
      WBInteraction000561808
      WBInteraction000561809
      WBInteraction000561810
      WBInteraction000561811
      WBInteraction000561812
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  Map_info: Map: II Position: -1.63708 Error: 0.021258
    Positive: Positive_clone: EEED8 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5279
        4538
      Pos_neg_data: 4469
    Pseudo_map_position
  Reference (11)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene