WormBase Tree Display for Variation: WBVar00275444

WBVar00275444 Evidence: Paper_evidence: WBPaper00025639
  Name: Public_name: yt2
    Other_name: CE26746:p.Trp270Ter
      EEED8.1.1:c.810G>A
    HGVSg: CHROMOSOME_II:g.5422271G>A
  Sequence_details: SMap: S_parent: Sequence: F07F6
    Flanking_sequences: tgataatattcgcgaggttgttaaaaaatg ggacaaatggaaaattcgacgcttcacgcc
    Mapping_target: F07F6
    Type_of_mutation: Substitution: g a Paper_evidence: WBPaper00025639
    SeqStatus: Sequenced
  Variation_type: Allele
  Origin: Species: Caenorhabditis elegans
    Strain: WBStrain00031149
    Laboratory: QA
    Status: Live
  Affects: Gene: WBGene00017132
    Transcript: EEED8.1.1 VEP_consequence: stop_gained
        VEP_impact: HIGH
        HGVSc: EEED8.1.1:c.810G>A
        HGVSp: CE26746:p.Trp270Ter
        cDNA_position: 841
        CDS_position: 810
        Protein_position: 270
        Exon_number: 6/9
        Codon_change: tgG/tgA
        Amino_acid_change: W/*
    Interactor: WBInteraction000502737
      WBInteraction000525290
  Genetics: Interpolated_map_position: II -1.63601
    Mapping_data: In_multi_point: 5279
  Description: Phenotype: WBPhenotype:0000052 Paper_evidence: WBPaper00025639
          WBPaper00028911
        Curator_confirmed: WBPerson48
          WBPerson557
        Remark: mel-47(yt2) mutants arrest as disorganized embryos with 50 to 80 cells of variable size. Paper_evidence: WBPaper00028911
            Curator_confirmed: WBPerson557
        Penetrance: Complete: Paper_evidence: WBPaper00025639
              Curator_confirmed: WBPerson48
        Maternal
      WBPhenotype:0001114 Paper_evidence: WBPaper00028911
        Curator_confirmed: WBPerson557
        Remark: mel-47 is required maternally for the proper execution of the early cell cycles. Paper_evidence: WBPaper00028911
            Curator_confirmed: WBPerson557
  Reference: WBPaper00028911
    WBPaper00025639
  Method: Substitution_allele