WormBase Tree Display for Gene: WBGene00017132

WBGene00017132 SMap: S_parent: Sequence: F07F6
  Identity: Version: 7
    Name: CGC_name: tofu-6
      Sequence_name: EEED8.1
      Molecular_name: EEED8.1
        EEED8.1.1
        CE26746
      Other_name: mel-2 Person_evidence: WBPerson314
        mel-47 Person_evidence: WBPerson629
            WBPerson314
        CELE_EEED8.1 Accession_evidence: NDB BX284602
      Public_name: tofu-6
    DB_info: Database: AceView gene 2F713
        WormQTL gene WBGene00017132
        NDB locus_tag CELE_EEED8.1
        NCBI gene 24104386
        RefSeq protein NM_001306578.5
        SwissProt UniProtAcc Q09293
        UniProt_GCRP UniProtAcc Q09293
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:58 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 01 Apr 2005 11:05:24 WBPerson2970 Name_change: CGC_name: tudr-1
        3 16 Oct 2006 16:56:31 WBPerson2970 Name_change: CGC_name: mel-47
                Other_name: tudr-1
        4 28 Mar 2014 15:50:22 WBPerson2970 Name_change: CGC_name: tofu-6
                Other_name: mel-47
        5 02 Sep 2014 12:40:48 WBPerson2970 Name_change: CGC_name: mel-47
                Other_name: tofu-6
        6 25 Mar 2015 15:33:40 WBPerson2970 Event: Acquires_merge: WBGene00003188
              Name_change: CGC_name: tofu-6
                Other_name: mel-2
        7 25 Mar 2015 15:34:24 WBPerson2970 Name_change: Other_name: mel-47
      Acquires_merge: WBGene00003188
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: tofu
    Reference_allele: WBVar00275444
      WBVar00088001
    Allele (31)
    Legacy_information: [C.elegansII] it20 : strict maternal effect embryonic lethal. OA1: it22. [Kemphues et al. 1988]
    Strain: WBStrain00023566
      WBStrain00031149
    RNASeq_FPKM (74)
    GO_annotation (33)
    Ortholog (23)
    Structured_description: Automated_description: Predicted to enable RNA binding activity. Involved in several processes, including embryonic cleavage; mitotic sister chromatid separation; and nucleic acid metabolic process. Located in nucleus and perinuclear region of cytoplasm. Expressed in germ line. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: EEED8.1
    Corresponding_transcript: EEED8.1.1
    Other_sequence: CRC09352_1
      CJC06104_1
      CR00454
      CBC05784_1
    Associated_feature: WBsf644193
      WBsf644194
      WBsf221278
  Experimental_info: RNAi_result: WBRNAi00113939 Inferred_automatically: RNAi_primary
      WBRNAi00043689 Inferred_automatically: RNAi_primary
      WBRNAi00022694 Inferred_automatically: RNAi_primary
      WBRNAi00103067 Inferred_automatically: RNAi_primary
      WBRNAi00033559 Inferred_automatically: RNAi_primary
      WBRNAi00008592 Inferred_automatically: RNAi_primary
      WBRNAi00113938 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr8287
      Expr14432
      Expr16061
      Expr1026068
      Expr1037359
      Expr1147673
      Expr2017448
      Expr2035587
    Drives_construct: WBCnstr00016926
      WBCnstr00037834
      WBCnstr00040803
      WBCnstr00042743
    Construct_product: WBCnstr00016926
      WBCnstr00037834
      WBCnstr00040803
      WBCnstr00042743
    Regulate_expr_cluster: WBPaper00056900:TOFU-6_interacting
    Microarray_results (20)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00037682:sma-2_sma-4_downregulated
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:germline-precursors_blastula-embryo_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00038289:oocyte_protein
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00040412:germline-regulated_daf-12_target
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044760:germline_specific
      WBPaper00044786:emr-1(RNAi);lem-2(tm1582)_downregulated
      WBPaper00045050:csr-1(hypomorph)_downregulated
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00046509:lin-35(n745)_upregulated
      WBPaper00046795:starvation_downregulated
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048988:neuron_expressed
      WBPaper00049498:npr-1(ur89)_regulated_6
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049942:hsf-1(RNAi)_upregulated
      WBPaper00050015:ifg-1(RNAi)_downregulated
      WBPaper00050193:cec-4(ok3124)_downregulated_L1
      WBPaper00050193:met-2(n4256)set-25(n5021)_downregulated_L1
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050686:glp-1(e2141)_downregulated
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:NMDA-neuron_enriched
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051461:pig-1(gm344)_upregulated
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00053713:Starvation-induced_postdauer_vs_control_downregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053814:25C_downregulated_OP50
      WBPaper00053814:25C_downregulated_PY79
      WBPaper00055103:thoc-5(wy822)_downregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00055862:antimycin_damt-1(gk961032)_regulated
      WBPaper00055971:nhl-2(ok818)_25C_upregulated
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056275:P.aeruginosa_downregulated_atf-7(qd22qd130)_dependent
      WBPaper00056275:P.aeruginosa_downregulated_pmk-1(km25)_dependent
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_upregulated_N2
      WBPaper00056826:hmc_biased
      WBPaper00056900:ERH-2_interacting
      WBPaper00056900:PID-3_interacting
      WBPaper00056900:TOFU-6_interacting
      WBPaper00056900:TOST-1_interacting
      WBPaper00057041:spc-1(cas971)_upregulated
      WBPaper00057154:HeatShock_downregulated_mRNA
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058598:mex-3(eu149)_downregulated
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00059328:mrps-5(RNAi)_downregulated_mRNA
      WBPaper00059566:wdr-23(mac32)_downregulated
      WBPaper00059609:malt-1_ilc-17.1_nfki-1_downregulated
      WBPaper00059664:srbc-48(ac23)_downregulated
      WBPaper00060445:ikb-1(nr2027)_upregulated_L4
      WBPaper00060445:nfki-1(cer1)_upregulated_L4
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060661:sensory-neuron_depleted
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00061007:HB101_downregulated
      WBPaper00061007:S.aquatilis_downregulated
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061203:spr-1(ok2144)_downregulated
      WBPaper00061274:hypergravity_10xg_upregulated
      WBPaper00061274:hypergravity_15xg_upregulated
      WBPaper00061340:Ciliated_amphid_neuron
      WBPaper00061340:Ciliated_non_amphid_neuron
      WBPaper00061340:I2_grandparent
      WBPaper00061340:Neuroblast_ASE_ASJ_AUA
      WBPaper00061340:Neuroblast_IL1_IL2
      WBPaper00061340:OLQ_grandparent
      WBPaper00061340:PLM_ALN_great_grandparent
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061466:nath-10(icb102)_upregulated
      WBPaper00061699:daf-18(ok480)_upregulated
      WBPaper00061818:ELKS-1_interacting
      WBPaper00062056:efl-1(se1)_upregulated
      WBPaper00062056:lin-35(n745)_upregulated
      WBPaper00062056:lin-36(we31)_upregulated
      WBPaper00062056:lin-36(we36)_upregulated
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062293:isp-1(qm150)_downregulated
      WBPaper00062325:etr-1(lq61)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062456:doxycycline_downregulated_CB4856_protein
      WBPaper00062456:doxycycline_downregulated_N2_protein
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00064071:NHR-49_interacting
      WBPaper00064080:let-7_miRNA_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
      WBPaper00064229:B.thuringiensis-Cry5Ba_downregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00065096:25C_vs_20C_upregulated
      WBPaper00065096:Day10_vs_Day1_upregulated
      WBPaper00065373:Cisplatin_upregulated_WT
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065373:sek-1(km4)_upregulated_Ref
      WBPaper00065841:3_0
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066110:tetraploid_vs_diploid_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_2
      WBPaper00025032:cluster_40
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00035227:heat_shock_regulated
      WBPaper00035479:daf-16(RNAi)_upregulated
      WBPaper00036123:Fluoranthene_regulated
      WBPaper00036130:mir-243_down_regulated
      WBPaper00036286:Pattern_B
      WBPaper00039866:ClassComp_daf-19_upregulated
      WBPaper00040426:CYD-1_CDK-4_upregulated
      WBPaper00040426:CYE-1_CDK-2AF_upregulated
      WBPaper00040963:TA300_down
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041906:I-3690_vs_OP50_3d
      WBPaper00041939:control_vs_EtBr-exposed_48h
      WBPaper00041939:control_vs_EtBr-exposed_51h
      WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
      WBPaper00041939:EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00053550:daf-19(m86)_upregulated_3-fold-embryo
      WBPaper00056330:mrps-5(RNAi)_downregulated
      [cgc5767]:cluster_3
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(186_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_ME
      [cgc6390]:Cluster_E
      [cgc6390]:oogenesis-enriched
    Interaction (472)
  Map_info: Map: II Position: -1.63708 Error: 0.021258
    Positive: Positive_clone: EEED8 Inferred_automatically: From sequence, transcript, pseudogene data
    Mapping_data: Multi_point: 5279
        4538
      Pos_neg_data: 4469
    Pseudo_map_position
  Reference (11)
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene