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WormBase Tree Display for Gene: WBGene00017054

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Name Class

WBGene00017054SMapS_parentSequenceD2024
IdentityVersion2
NameCGC_namegstk-2Person_evidenceWBPerson1763
Sequence_nameD2024.7
Molecular_nameD2024.7
D2024.7.1
CE04296
Other_nameCELE_D2024.7Accession_evidenceNDBBX284604
Public_namegstk-2
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:58WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
227 Feb 2008 14:43:32WBPerson2970Name_changeCGC_namegstk-2
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgstk
Allele (31)
RNASeq_FPKM (74)
GO_annotation (15)
Ortholog (37)
ParalogWBGene00014251Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00020314Caenorhabditis elegansFrom_analysisPanther
Structured_descriptionConcise_descriptiongstk-2 encodes one of two C. elegans kappa class glutathione transferases; while gstk-2(RNAi) animals exhibit no obvious developmental or morphological abnormalities, animals doubly mutant for gstk-2 and gstk-1 exhibit decreased respiration and a lower concentration of the monounsaturated fatty acid cis-vaccenic acid; GSTK-2 is expressed primarily in the pharynx, muscles, and epidermis and localizes to mitochondria.Paper_evidenceWBPaper00035091
Curator_confirmedWBPerson1843
Date_last_updated14 Aug 2009 00:00:00
Automated_descriptionPredicted to enable glutathione peroxidase activity and glutathione transferase activity. Predicted to be involved in glutathione metabolic process. Located in mitochondrion. Expressed in body wall musculature; intestine; and pharynx. Is an ortholog of human GSTK1 (glutathione S-transferase kappa 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSD2024.7
Corresponding_transcriptD2024.7.1
Other_sequenceCBC12524_1
Associated_featureWBsf996915
WBsf996916
WBsf230235
WBsf230236
WBsf230237
Experimental_infoRNAi_result (11)
Expr_patternExpr8776
Expr1021154
Expr1037327
Expr1147459
Expr2012335
Expr2030572
Drives_constructWBCnstr00013514
WBCnstr00027605
Construct_productWBCnstr00013514
WBCnstr00027605
Microarray_results (21)
Expression_clusterWBPaper00031040:Cluster_5
WBPaper00031040:TGF-beta_adult_upregulated
WBPaper00032031:DConiospora_downregulated_cDNA_24h
WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
WBPaper00037950:all-neurons_L1-larva_expressed
WBPaper00037950:AVA-neuron_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L1-larva_expressed
WBPaper00037950:bodywall-muscle_L2-larva_expressed
WBPaper00037950:coelomocytes_embryo_enriched
WBPaper00037950:coelomocytes_L1-larva_expressed
WBPaper00037950:coelomocytes_L2-larva_expressed
WBPaper00037950:dopaminergic-neurons_L1-larva_expressed
WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
WBPaper00037950:dopaminergic-neurons_larva_enriched
WBPaper00037950:excretory-cell_L2-larva_expressed
WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
WBPaper00037950:hypodermis_L1-larva_expressed
WBPaper00037950:hypodermis_L3-L4-larva_expressed
WBPaper00037950:intestine_L1-larva_expressed
WBPaper00037950:intestine_L2-larva_expressed
WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
WBPaper00038438:Harposporium_24hr_downregulated_RNAseq
WBPaper00040221:DAF-12_target_ALF4
WBPaper00042561:smgl-1(RNAi)_downregulated
WBPaper00044426:rotenone_24h_upregulated
WBPaper00044736:flat_dev_expression
WBPaper00045314:S.aureus-induced_N2
WBPaper00045390:tunicamycin_downregulated
WBPaper00045390:ubc-9(RNAi)_downregulated
WBPaper00045417:128Q-huntingtin_upreglated
WBPaper00045774:clk-1_downregulated
WBPaper00046497:B.thuringiensis_0.1mix_upregulated_6h
WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
WBPaper00046497:B.thuringiensis_0.5mix_upregulated_6h
WBPaper00046497:B.thuringiensis_0.5mix_upregulated_12h
WBPaper00048923:Aging_regulated
WBPaper00049545:cco-1(RNAi)_downregulated
WBPaper00049545:jmjd-3.1(+)_downregulated
WBPaper00049942:hsf-1(RNAi)_downregulated
WBPaper00050468:hlh-30-dependent_Cry5B_regulated
WBPaper00050488:adult_vs_dauer_regulated_N2_20C
WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C
WBPaper00050801:DAF-16_dauer_regulome
WBPaper00050990:GABAergic-neuron_expressed
WBPaper00050990:intestine_expressed
WBPaper00051558:aging_regulated
WBPaper00052884:emb-4(hc60)_upregulated
WBPaper00053184:sma-2(rax5)_upregulated
WBPaper00053184:sma-4(rax3)_upregulated
WBPaper00053302:stavudine_24h_regulated
WBPaper00053302:zidovudine_72h_regulated
WBPaper00053388:dauer_regulated_Cluster4
WBPaper00053599:female_vs_male_downregulated
WBPaper00053810:daf-2(e1370)_upregulated
WBPaper00053810:nuo-6(qm200)_upregulated
WBPaper00055354:eat-2(ad1116)_downregulated
WBPaper00055354:Psora-Allantoin_downregulated
WBPaper00055354:Rapamycin-Allantoin_downregulated
WBPaper00055354:Rapamycin-Rifampicin-Psora_upregulated
WBPaper00055354:Rapamycin-Rifampicin_upregulated
WBPaper00055648:sperm_expressed
WBPaper00056090:E.faecalis_upregulated_hpx-2(dg047)
WBPaper00056090:E.faecalis_upregulated_N2
WBPaper00056139:soil-microbiota_downregulated
WBPaper00056161:male_enriched_siRNA
WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
WBPaper00056471:S.aureus-4h_downregulated_N2
WBPaper00056826:hmc_biased
WBPaper00056997:nmad-1(ok3133)_upregulated_germline_25C
WBPaper00057041:unc-70(cas983)_downregulated
WBPaper00057143:ztf-11(RNAi)_upregulated
WBPaper00057288:iff-1(RNAi)_upregulated_transcript
WBPaper00058711:wdr-5(ok1417)_downregulated
WBPaper00058948:PA14_downregulated
WBPaper00059567:olrn-1(ums9)_regulated
WBPaper00059987:Wounding_upregulated
WBPaper00060100:SiNP_downregulated_mRNA
WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
WBPaper00060526:plp-1(ok2155)_downregulated
WBPaper00060811:L1_vs_adult_upregulated_neural
WBPaper00061081:E.faecalis_upregulated_N2
WBPaper00061340:BWM_anterior
WBPaper00061527:acy-2-F35C5.11
WBPaper00061699:daf-18(ok480)_downregulated
WBPaper00061753:csr-1(tor159)_upregulated_25C
WBPaper00062159:hda-2(ok1479)_upregulated
WBPaper00062193:skn-1(RNAi)_upregulated
WBPaper00062325:muscle_enriched_coding-RNA
WBPaper00062345:bortezomib_4h_downregulated_N2
WBPaper00062590:Aging_downregulated_hypodermis
WBPaper00062590:Aging_downregulated_neuron
WBPaper00064005:starvation_upregulated_aptf-1(gk794)_mRNA
WBPaper00064005:starvation_upregulated_N2_mRNA
WBPaper00064071:NHR-49_interacting
WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
WBPaper00064088:Day-1-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064088:Day-3-adult_vs_L4_upregulated_fem-3(q20)
WBPaper00064130:Beta-Amyloid_upregulated_protein
WBPaper00065096:Day10_vs_Day1_downregulated
WBPaper00065373:sek-1(km4)_downregulated_cisplatin
WBPaper00065373:sek-1(km4)_upregulated_Ref
cgc4489_group_17
WBPaper00026929:Resveratrol_regulated_daf-16
WBPaper00026929:sir-2.1_overexpression_regulated
WBPaper00030839:Embryo_Pan_Neuronal
WBPaper00030985:Enterococcus_faecalis_downregulated
WBPaper00031003:0hr_muscle_enriched
WBPaper00031003:24hr_muscle_enriched
WBPaper00031003:hlh_1_enriched
WBPaper00031003:total_muscle_enriched
WBPaper00032948:StarveUp1
WBPaper00035227:heat_shock_regulated
WBPaper00036286:Pattern_F
WBPaper00038172:tax-6null_up_regulated
WBPaper00040184:hcf-1up_sir-2.1up_daf-2up
WBPaper00040426:CYD-1_CDK-4_upregulated
WBPaper00040963:Q100_up
WBPaper00040963:Q200_up
WBPaper00041606:CE_S.marcescens_regulated
WBPaper00041939:control_vs_EtBr-exposed_48h
WBPaper00041939:control_vs_UVC-EtBr-exposed_48h
WBPaper00041939:EtBr-exposed_vs_UVC-exposed_48h
WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_3h
WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_48h
WBPaper00042234:xpa-1_upregulated
WBPaper00042274:tbx-2(bx59)_upregulated
WBPaper00044535:male_upregulated
WBPaper00045960:L4-lethargus_upregulated
WBPaper00047070:N2_starvation_upregulated
WBPaper00053236:Starvation_regulated_N2
InteractionWBInteraction000151486
WBInteraction000215297
WBInteraction000371371
WBInteraction000387413
WBInteraction000524867
WBInteraction000524868
Map_infoMapIVPosition3.31178Error0.000439
PositivePositive_cloneD2024Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00035091
WBPaper00038491
WBPaper00055090
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene