WormBase Tree Display for Gene: WBGene00017016

WBGene00017016 SMap: S_parent: Sequence: D1014
  Identity: Version: 3
    Name: CGC_name: snap-1 Person_evidence: WBPerson451
      Sequence_name: D1014.3
      Molecular_name: D1014.3a
        D1014.3a.1
        CE38494
        D1014.3b
        CE53052
        D1014.3b.1
        D1014.3b.2
        D1014.3b.3
      Other_name: phi-29 Person_evidence: WBPerson2582
        CELE_D1014.3 Accession_evidence: NDB BX284605
      Public_name: snap-1
    DB_info: Database: AceView gene 5I613
        WormQTL gene WBGene00017016
        WormFlux gene WBGene00017016
        NDB locus_tag CELE_D1014.3
        Panther gene CAEEL|WormBase=WBGene00017016|UniProtKB=Q18921
          family PTHR13768
        NCBI gene 179193
        RefSeq protein NM_001392555.1
            NM_072698.7
        TrEMBL UniProtAcc A0A486WXT8
            Q18921
        UniProt_GCRP UniProtAcc Q18921
        OMIM gene 611270
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:58 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 17 Mar 2005 13:54:35 WBPerson2970 Name_change: Other_name: phi-29
        3 07 Sep 2006 08:05:50 WBPerson2970 Name_change: CGC_name: snap-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: snap
    Allele (39)
    RNASeq_FPKM (74)
    GO_annotation (12)
    Contained_in_operon: CEOP5180
    Ortholog (48)
    Paralog: WBGene00013345 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00044794 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable soluble NSF attachment protein activity and syntaxin binding activity. Involved in IRE1-mediated unfolded protein response. Predicted to be located in membrane. Predicted to be part of SNARE complex. Human ortholog(s) of this gene implicated in Alzheimer's disease; Down syndrome; and developmental and epileptic encephalopathy 107. Is an ortholog of human NAPA (NSF attachment protein alpha) and NAPB (NSF attachment protein beta). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0070393 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:15751)
      DOID:10652 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:15751)
      DOID:14250 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:15751)
  Molecular_info: Corresponding_CDS: D1014.3a
      D1014.3b
    Corresponding_CDS_history: D1014.3:wp142
    Corresponding_transcript: D1014.3a.1
      D1014.3b.1
      D1014.3b.2
      D1014.3b.3
    Other_sequence (35)
    Associated_feature: WBsf646987
      WBsf646988
      WBsf661465
      WBsf661466
      WBsf981966
      WBsf1000585
      WBsf232064
      WBsf232065
  Experimental_info: RNAi_result (32)
    Expr_pattern: Expr5609
      Expr1016527
      Expr1037312
      Expr1147322
      Expr2015937
      Expr2034170
    Drives_construct: WBCnstr00004056
      WBCnstr00027636
    Construct_product: WBCnstr00027636
    Microarray_results (21)
    Expression_cluster: WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00032097:CGH-1-associated-mRNA
      WBPaper00032528:L3_enriched
      WBPaper00037950:A-class-motor-neurons_L2-larva_expressed
      WBPaper00037950:A-class-motor-neurons_larva_enriched
      WBPaper00037950:all-neurons_L1-larva_expressed
      WBPaper00037950:all-neurons_L2-larva_expressed
      WBPaper00037950:all-neurons_larva_enriched
      WBPaper00037950:AVA-neuron_L1-larva_expressed
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00040221:DAF-12_target_ALF4
      WBPaper00044128:daf-2(e1370)_upregulated
      WBPaper00044128:DietaryRestriction_upregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045521:Gender_Neutral
      WBPaper00046012:tdp-1(ok803)_upregulated
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049083:post-dauer-development_upregulated
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:body-muscle_expressed
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00050990:NMDA-neuron_expressed
      WBPaper00050990:pharynx_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_cytoplasm_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053302:zidovudine_72h_regulated
      WBPaper00055049:S.gordonii_upregulated
      WBPaper00055565:AVK_enriched
      WBPaper00055648:germline_expressed
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056826:SGP_biased
      WBPaper00058598:sin-3(tm1276)_upregulated
      WBPaper00059027:neuron-synapses_depleted
      WBPaper00059356:BAZ-2_SET-6_interacting
      WBPaper00059471:EGL-43_interacting
      WBPaper00059605:MUT-16_interacting
      WBPaper00059763:neuron_expressed
      WBPaper00060661:sensory-neuron_enriched
      WBPaper00060683:hlh-11(ko1)_downregulated
      WBPaper00060811:L1_vs_adult_upregulated_neural
      WBPaper00061203:sin-3(tm1276)_downregulated
      WBPaper00061340:RME
      WBPaper00061527:hars-1-cct-4_20449
      WBPaper00061651:PDE_enriched
      WBPaper00061651:PVW_enriched
      WBPaper00061651:VB01_enriched
      WBPaper00061651:VB_enriched
      WBPaper00061818:ELKS-1_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064163:ZNFX-1_interacting_embryo
      WBPaper00064716:paraquat_upregulated
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065258:anchor-cell_enriched
      WBPaper00065373:sek-1(km4)_upregulated_cisplatin
      WBPaper00065993:glp-1(e2141)_downregulated
      cgc4489_group_7
      WBPaper00006465:II_ethanol_late_induction
      WBPaper00025032:cluster_53
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00026980:intestine_enriched
      WBPaper00030839:Larval_Pan_Neuronal
      WBPaper00030985:Enterococcus_faecalis_upregulated
      WBPaper00034739:N2moreDR1350
      WBPaper00035905:FBF-1_Associated
      WBPaper00036286:Pattern_B
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00048989:N2_rapamycin_downregulated
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(186_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_MD
      [cgc5767]:expression_class_ME
      [cgc6390]:Cluster_A
      [cgc6390]:herm_sex-enriched
    Interaction (85)
  Map_info: Map: V Position: 1.04508 Error: 0.011611
    Positive: Positive_clone: D1014 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene