WormBase Tree Display for Gene: WBGene00016013

WBGene00016013 SMap: S_parent: Sequence: C23G10
  Identity: Version: 2
    Name: CGC_name: ugt-66 Person_evidence: WBPerson1818
      Sequence_name: C23G10.6
      Molecular_name: C23G10.6
        C23G10.6.1
        CE45015
      Other_name: CELE_C23G10.6 Accession_evidence: NDB BX284603
      Public_name: ugt-66
    DB_info: Database (13)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:56 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 07 Jun 2018 14:30:09 WBPerson1983 Name_change: CGC_name: ugt-66
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: ugt
    Allele (30)
    Strain: WBStrain00047636
    RNASeq_FPKM (74)
    GO_annotation: 00092948
      00092949
      00092950
      00092951
      00092952
      00092953
      00092954
      00092955
      00121706
    Contained_in_operon: CEOP3826
    Ortholog (93)
    Paralog (74)
    Structured_description: Automated_description: Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in osteoporosis. Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:11476 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:12547)
  Molecular_info: Corresponding_CDS: C23G10.6
    Corresponding_CDS_history: C23G10.6:wp165
      C23G10.6:wp214
    Corresponding_transcript: C23G10.6.1
    Other_sequence: CJC12136_1
      Oden_isotig21949
      EX563196.1
      EX561522.1
      PPC07649_1
      CJC03587_1
    Associated_feature: WBsf666977
      WBsf226778
  Experimental_info: RNAi_result: WBRNAi00041012 Inferred_automatically: RNAi_primary
      WBRNAi00005373 Inferred_automatically: RNAi_primary
      WBRNAi00011052 Inferred_automatically: RNAi_primary
      WBRNAi00029111 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1021099
      Expr1145055
      Expr2001011
      Expr2019229
    Drives_construct: WBCnstr00028386
    Construct_product: WBCnstr00028386
    Microarray_results (16)
    Expression_cluster: WBPaper00032031:DConiospora_downregulated_OligoArray_24h
      WBPaper00033065:clk-1(qm30)_upregulated
      WBPaper00037950:BAG-neuron_blastula-embryo_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:dopaminergic-neurons_larva_enriched
      WBPaper00037950:GABAergic-motor-neurons_L1-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00038438:D.coniospora_12hr_downregulated_RNAseq
      WBPaper00038438:E.faecalis_24hr_upregulated_RNAseq
      WBPaper00038438:Harposporium_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_RNAseq
      WBPaper00038438:S.marcescens_24hr_upregulated_TilingArray
      WBPaper00040560:hpl-2_L3_downregulated
      WBPaper00042215:wdr-23(tm1817)_upregulated
      WBPaper00042477:prp-8(RNAi)_upregulated_RNAseq
      WBPaper00042477:rsr-2(RNAi)_upregulated_RNAseq
      WBPaper00042561:smgl-1(RNAi)_upregulated
      WBPaper00044037:eat-2_regulated_nhr-62_dependent
      WBPaper00044037:eat-2_upregulated
      WBPaper00044246:pgrn-1_ced-3_ced-1_downregulated
      WBPaper00044260:1-methylnicotinamide_upregulated
      WBPaper00044316:CH3HgCl_7.5uM_upregulated
      WBPaper00044316:HgCl2_20uM_upregulated
      WBPaper00044578:reduced-humidity_downregulated_microarray
      WBPaper00044736:flat_dev_expression
      WBPaper00044743:wdr-23_neuron_upregulated
      WBPaper00044786:lem-2(tm1582)_upregulated
      WBPaper00045050:csr-1(hypomorph)_downregulated
      WBPaper00045050:drh-3 (ne4253)_downregulated
      WBPaper00045390:tunicamycin_upregulated
      WBPaper00045390:ubc-9(RNAi)_upregulated
      WBPaper00045401:N.parisii_64h_downregulated
      WBPaper00045417:128Q-huntingtin_upreglated
      WBPaper00045420:fertilization_downregulated_transcript
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_upregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00046337:polysomal_daf-2_vs_daf-2;daf-16_downregulated
      WBPaper00046337:polysomal_N2_vs_daf-2_downregulated
      WBPaper00047131:daf-2(e1370)_upregulated_hel-1(gk148684)-background
      WBPaper00047131:daf-2(e1370)_upregulated_N2-background
      WBPaper00047132:glp-1(ts)-25C_upregulated
      WBPaper00048611:MnCl2_downregulated
      WBPaper00048926:miaserin_upregulated_adult-day3
      WBPaper00048926:miaserin_upregulated_adult-day5
      WBPaper00048926:miaserin_upregulated_adult-day10
      WBPaper00049498:npr-1(ur89)_regulated_2
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049635:dop-1(vs100)_downregulated
      WBPaper00049736:15deg-then-25deg(12hr)_upregulated_N2
      WBPaper00049736:daf-2(e1370)_upregulated_15deg-then-25deg(12hr)
      WBPaper00049920:Glucose-Diet_upregulated_hyl-2(tm2031)
      WBPaper00049920:Glucose-Diet_upregulated_N2
      WBPaper00050080:rbr-2(tm3141)_downregulated
      WBPaper00050096:P.aeruginosa_downregulated
      WBPaper00050193:dpy-27(RNAi)_upregulated_L1
      WBPaper00050332:juglone_upregulated
      WBPaper00050332:skn-1(RNAi)_downregulated
      WBPaper00050344:AFD-neuron_enriched
      WBPaper00050344:ASER-neuron_enriched
      WBPaper00050344:PLM-neuron_enriched
      WBPaper00050488:20C_vs_25C_regulated_mir-34(gk437)_adult
      WBPaper00050488:20C_vs_25C_regulated_mir-34(OverExpression)_adult
      WBPaper00050488:20C_vs_25C_regulated_N2_adult
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_adult_25C
      WBPaper00050726:OsmoticStress_regulated_Food
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050726:starvation_regulated_HighSalt
      WBPaper00050859:upregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:upregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050859:upregulated_pgl-1(ct131)_vs_control_day1-adult
      WBPaper00050928:male-mating_downregulated
      WBPaper00050990:hypodermis_enriched
      WBPaper00050990:hypodermis_expressed
      WBPaper00051021:4-bromodiphenyl-ether_upregulated
      WBPaper00051257:Levamisole_upregulated
      WBPaper00051265:F4_hrde-1(tm1200)_upregulated
      WBPaper00051404:alg-1(gk214)_upregulated
      WBPaper00051404:alg-2(ok304)_upregulated
      WBPaper00051558:fog-2(q71)_regulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(icb38)_downregulated
      WBPaper00053295:lin-22(ot269)_downregulated
      WBPaper00053318:mir-71(n4115)_downregulated_mRNA
      WBPaper00053388:dauer_regulated_Cluster6
      WBPaper00053810:clk-1(qm30)_downregulated
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00053888:drh-3(rrr2)_downregulated
      WBPaper00055103:thoc-5(wy822)_upregulated
      WBPaper00055226:ADR-2_target_N2
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Rapamycin-Metformin_downregulated
      WBPaper00055354:Rapamycin-Psora-Allantoin_upregulated
      WBPaper00055354:Rapamycin-Psora_upregulated
      WBPaper00055354:Rapamycin_downregulated
      WBPaper00055354:Rifampicin-Allantoin_downregulated
      WBPaper00055354:Rifampicin-Psora_upregulated
      WBPaper00055386:daf-2(e1370)_upregulated
      WBPaper00055482:pmt-2(RNAi)_upregulated
      WBPaper00055827:daf-2(e1370)_upregulated
      WBPaper00055941:nuo-6(qm200);atfs-1(gk3094)_downregulated
      WBPaper00055941:nuo-6(qm200)_downregulated
      WBPaper00055971:nhl-2(ok818)_25C_downregulated
      WBPaper00056167:Cry5B_downregulated
      WBPaper00056275:P.aeruginosa_downregulated
      WBPaper00056290:hsp-6(mg585)_upregulated
      WBPaper00056290:mdt-15(mg584)_upregulated
      WBPaper00056443:DietaryRestriction_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00057068:Cadmium_upregulated
      WBPaper00057196:raga-1(ok386)_upregulated)
      WBPaper00057347:nhr-14(tm1473)_downreglated
      WBPaper00058598:mex-1(or286)_upregulated
      WBPaper00058598:mex-3(eu149)_upregulated
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058648:Y37A1B.5(RNAi)_upregulated
      WBPaper00058711:paraquat_upregulated
      WBPaper00058711:skn-1(lax188)_downregulated
      WBPaper00058711:wdr-5(ok1417)_upregulated
      WBPaper00058948:npr-8(ok1439)_downregulated_OP50
      WBPaper00058948:PA14_upregulated
      WBPaper00059253:stearic-acid_upregulated
      WBPaper00059253:sucrose_stearic-acid_upregulated
      WBPaper00059426:Ag-nanoparticles_downregulated
      WBPaper00059604:fluvastatin_downregulated_N2
      WBPaper00059728:5ug_cholesterol_upregulated
      WBPaper00059728:20ug_cholesterol_upregulated
      WBPaper00059735:glucose_downregulated_lpin-1(RNAi)
      WBPaper00059739:hira-1(gk835598)_downregulated_L4
      WBPaper00059824:rnp-6(dh1127)_regulated_OP50
      WBPaper00059839:S.maltophilia_regulated
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060399:pqm-1(ok485)_upregulated_CoCl2_6hr
      WBPaper00060434:pH4.33_vs_pH6.33_uprgulated
      WBPaper00060526:plp-1(ok2155)_upregulated
      WBPaper00060683:hlh-11(ko1)_upregulated
      WBPaper00060703:nas-38(ok3407)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00060871:M.humicola-extract_1h_regulated
      WBPaper00060909:atfs-1(cmh15)_upregulated
      WBPaper00060909:atfs-1(et18)_downregulated
      WBPaper00060921:cat-2(e1112)_downregulated
      WBPaper00061007:S.aquatilis_upregulated
      WBPaper00061040:eat-2(ad1116)_downregulated
      WBPaper00061081:skpo-1(ok1640)_upregulated_OP50
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061203:spr-1(ok2144)_upregulated
      WBPaper00061274:hypergravity_15xg_downregulated
      WBPaper00061340:ILso
      WBPaper00061340:rect_D
      WBPaper00061340:Tail_hypodermis
      WBPaper00061341:28C_24h_upregulated
      WBPaper00061341:28C_48h_upregulated
      WBPaper00061527:snt-4_17845-T27C4.1
      WBPaper00061590:CGP37157_upregulated
      WBPaper00061613:human-amyloid-beta_alpha-Synuclein(A53T)_downregulated
      WBPaper00061753:csr-1(tor159)_downregulated_20C
      WBPaper00061753:csr-1(tor159)_downregulated_25C
      WBPaper00061853:osm-3(dh441)_downregulated
      WBPaper00061853:osm-3(dh441)_downregulated_tunicamycin
      WBPaper00061995:mter-4(syb3662syb3403)_downregulated
      WBPaper00062078:NMR-HspB1_regulated
      WBPaper00062156:jmjd-1.2(zr1010)_upregulated
      WBPaper00062156:jmjd-5(zr1234)_upregulated
      WBPaper00062159:hda-2(ok1479)_upregulated
      WBPaper00062167:mbl-1(tm1563)_downregulated
      WBPaper00062193:daf-16(RNAi)_upregulated
      WBPaper00062305:P.brevicompactum_downregulated
      WBPaper00062325:etr-1(lq61)_upregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062345:bortezomib_4h_downregulated_zip-1(jy13)
      WBPaper00062440:crh-1(n3315)_downregulated
      WBPaper00062440:crh-1(syb385)_downregulated
      WBPaper00062497:xpf-1(tm2842)_downregulated
      WBPaper00062585:hlh-26(ok1453)_upregulated_E.faecium
      WBPaper00062672:let-418(n3536)dcp-66(RNAi)_upregulated
      WBPaper00064088:Day-1-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_upregulated_glp-1(e2141)
      WBPaper00064156:lbp-3(overexpress)_upregulated
      WBPaper00064505:tamoxifen_downregulated
      WBPaper00064539:nhr-114(gk849)_downregulated
      WBPaper00064716:paraquat_downregulated
      WBPaper00064727:daf-2(e1370)_upregulated
      WBPaper00064769:him-17(me24)_upregulated
      WBPaper00064788:ketamine_upregulated
      WBPaper00064871:hypoxia_upregulated_F1
      WBPaper00064933:bcf-1(ylf1)_upregulated_transcript
      WBPaper00065029:cadmium_upregulated
      WBPaper00065096:25C_vs_20C_downregulated
      WBPaper00065096:Day10_vs_Day1_downregulated
      WBPaper00065096:npr-8(ok1439)_upregulated_Day1_25C
      WBPaper00065288:mdt-15(tm2182)_downregulated
      WBPaper00065315:mating_downregulated_Day2-7
      WBPaper00065392:Lb.reuteri_upregulated
      WBPaper00065392:P.pentosaceus_upregulated
      WBPaper00065749:Heat-Shock_downregulated_N2
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065975:P-body_vs_WholeAnimal_depleted
      WBPaper00065993:glp-1(e2141)_upregulated
      WBPaper00065995:M.humicola-extract_downregulated_N2
      WBPaper00066038:mip-1(how5)_upregulated
      WBPaper00066062:xrep-4(lax137)_upregulated
      WBPaper00066110:Cisplatin_upregulated_diploid
      WBPaper00066110:Doxorubicin_upregulated_diploid
      WBPaper00066110:tetraploid_vs_diploid_upregulated
      WBPaper00066146:germline-inx-14(RNAi)_upregulated_PA14
      WBPaper00066204:CdCl2_upregulated_mRNA
      WBPaper00066232:hsf-1(RNAi)_upregulated_ash-2
      WBPaper00066232:hsf-1(RNAi)_upregulated_WT
      cgc4489_group_23
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00024671:AFD_AWB_vs_unsorted_upregulated
      WBPaper00024671:AFD_vs_AWB_upregulated
      WBPaper00028789:PA14_vs_gacA_downregulated_4hr
      WBPaper00028789:PA14_vs_gacA_downregulated_8hr
      WBPaper00028789:PA14_vs_OP50_downregulated_4hr
      WBPaper00028789:PA14_vs_OP50_downregulated_8hr
      WBPaper00030985:Enterococcus_faecalis_upregulated
      WBPaper00030985:Erwinia_carotovora_upregulated
      WBPaper00031184:acrylamide_upregulated
      WBPaper00031252:AIN-1_IP_enriched
      WBPaper00031252:AIN-2_IP_enriched
      WBPaper00032165:differentially_expressed_with_age_medoid_4
      WBPaper00034739:N2lessDR1350
      WBPaper00035084:embryo_enriched_AIN-2_IP
      WBPaper00035084:L1_enriched_AIN-2_IP
      WBPaper00035084:L2_enriched_AIN-2_IP
      WBPaper00035084:L3_enriched_AIN-2_IP
      WBPaper00035084:L4_enriched_AIN-2_IP
      WBPaper00036123:Fluoranthene_regulated
      WBPaper00036130:mir-243_up_regulated
      WBPaper00036286:Pattern_C
      WBPaper00036464:S.aureus-RN6390_regulated
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2up
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040603:tdp-1(lf)_down_vs_N2_FC_1.2
      WBPaper00041207:CE_dauer_up
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00042331:a-SWCNTs_downregulated
      WBPaper00044535:male_downregulated
      WBPaper00045263:0.1mM-paraquat_downregulated
      WBPaper00045263:isp-1(qm150)_downregulated
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00045263:ProLongevity-mtROS_downregulated
      WBPaper00046083:ogt-1(ok1474)_OP50_downregulated
      WBPaper00046083:pmk-1(km25)_OP50_downregulated
      WBPaper00046853:AOBr_M.aeruginosa-batch-culture_downregulated
      WBPaper00047021:MWCNT_upregulated
      WBPaper00048929:ethosuximide_upregulated
      WBPaper00048989:eat-2(ad465)_downregulated_in-DMSO
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00053827:pyoverdine_upregulated
      WBPaper00055899:2,4-Dinitroanisole_regulated
      WBPaper00055899:nitroguanidine_regulated
      WBPaper00056330:mrps-5(RNAi)_upregulated
      [cgc6390]:Cluster_C
      [cgc6390]:male_sex-enriched
    Interaction: WBInteraction000303914
      WBInteraction000504120
      WBInteraction000541045
  Map_info: Map: III Position: -1.40939
    Positive: Positive_clone: C23G10 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
    WBPaper00055433
    WBPaper00062838
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene