WormBase Tree Display for Gene: WBGene00015814
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| WBGene00015814 | SMap | S_parent | Sequence | C16A3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | oatr-1 | Paper_evidence | WBPaper00040135 | |||||
| Sequence_name | C16A3.10 | ||||||||
| Molecular_name | C16A3.10 | ||||||||
| C16A3.10.1 | |||||||||
| CE04010 | |||||||||
| C16A3.10.2 | |||||||||
| Other_name | orn-1 | Paper_evidence | WBPaper00040135 | ||||||
| CELE_C16A3.10 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | oatr-1 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:56 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 09 Aug 2016 14:35:06 | WBPerson2970 | Name_change | CGC_name | oatr-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | oatr | ||||||||
| Allele (26) | |||||||||
| Strain | WBStrain00001310 | ||||||||
| WBStrain00051644 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (45) | |||||||||
| Paralog | WBGene00001794 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00020139 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00020382 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | C16A3.10 encodes an ornithine transaminase orthologous to the human gene OAT (ornithine aminotransferase); the product of C16A3.10 is predicted to catalyze the conversion of ornithine to L-glutamate-5-semialdehyde in the process of arginine-to-proline conversion. | Paper_evidence | WBPaper00004637 | |||||
| WBPaper00040135 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 30 Aug 2011 00:00:00 | ||||||||
| Automated_description | Predicted to enable identical protein binding activity; ornithine-oxo-acid transaminase activity; and pyridoxal phosphate binding activity. Predicted to be involved in arginine catabolic process to glutamate and arginine catabolic process to proline via ornithine. Predicted to be located in cytoplasm. Expressed in tail. Used to study amino acid metabolic disorder. Human ortholog(s) of this gene implicated in gyrate atrophy. Is an ortholog of human OAT (ornithine aminotransferase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:9252 | Homo sapiens | Paper_evidence | WBPaper00040135 | ||||
| WBPaper00059575 | |||||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 13 Mar 2023 00:00:00 | ||||||||
| Potential_model | DOID:1415 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8091) | |||||
| Disease_relevance | C16A3.10 encodes an ornithine transaminase orthologous to the human gene OAT (ornithine aminotransferase) which when mutated leads to ornithinemia and gyrate atrophy. | Homo sapiens | Accession_evidence | OMIM | 258870 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 30 Aug 2011 00:00:00 | ||||||||
| Models_disease_in_annotation | WBDOannot00000008 | ||||||||
| Models_disease_asserted | WBDOannot00001378 | ||||||||
| Molecular_info | Corresponding_CDS | C16A3.10 | |||||||
| Corresponding_CDS_history | C16A3.10b:wp255 | ||||||||
| C16A3.10c:wp255 | |||||||||
| Corresponding_transcript | C16A3.10.1 | ||||||||
| C16A3.10.2 | |||||||||
| Other_sequence (83) | |||||||||
| Associated_feature | WBsf651120 | ||||||||
| WBsf666987 | |||||||||
| WBsf992744 | |||||||||
| WBsf992745 | |||||||||
| WBsf992746 | |||||||||
| WBsf992747 | |||||||||
| WBsf1015085 | |||||||||
| WBsf1015086 | |||||||||
| WBsf1015087 | |||||||||
| WBsf226809 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00110479 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00110480 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00010816 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00110478 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00028943 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00110481 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00040651 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00005376 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00090612 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1413 | ||||||||
| Chronogram2045 | |||||||||
| Expr5273 | |||||||||
| Expr5274 | |||||||||
| Expr5275 | |||||||||
| Expr1021415 | |||||||||
| Expr1036771 | |||||||||
| Expr1144706 | |||||||||
| Expr2014589 | |||||||||
| Expr2032822 | |||||||||
| Drives_construct | WBCnstr00002202 | ||||||||
| WBCnstr00002203 | |||||||||
| WBCnstr00004174 | |||||||||
| WBCnstr00004252 | |||||||||
| WBCnstr00028545 | |||||||||
| Construct_product | WBCnstr00028545 | ||||||||
| Regulate_expr_cluster | WBPaper00040135:orn-1(RNAi)_downregulated | ||||||||
| WBPaper00040135:orn-1(RNAi)_upregulated | |||||||||
| Microarray_results (33) | |||||||||
| Expression_cluster (177) | |||||||||
| Interaction (94) | |||||||||
| Map_info | Map | III | Position | -1.30449 | |||||
| Positive | Positive_clone | C16A3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00040135 | |||||||||
| WBPaper00049828 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00059575 | |||||||||
| WBPaper00061536 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
